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ChemicalBook >> CAS DataBase List >> Mertansine

Mertansine

Mertansine price.
  • $66 - $1375
  • Product name: Mertansine
  • CAS: 139504-50-0
  • MF: C35H48ClN3O10S
  • MW: 738.29
  • EINECS:
  • MDL Number:MFCD28398157
  • Synonyms:N2'-deacetyl-N2'-(3-Mercapto-1-oxopropyl)-Maytansine;DM1 Mertansine;Maytansine DM1;Maytansine, N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-;DM1 Compound;UNII-DDZ29HGH0E;(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] (2S)-2-[methyl(3-sulfanylpropanoyl)amino]propanoate;DM1 top3
27 prices
Selected condition：
Brand
  • AK Scientific
  • AvaChem
  • Biosynth Carbosynth
  • BroadPharm
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product numberSYN5584
  • Product descriptionMertansine
  • Packaging100mg
  • Price$1296
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3948
  • Product descriptionMertansine
  • Packaging5mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3948
  • Product descriptionMertansine
  • Packaging10mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3948
  • Product descriptionMertansine
  • Packaging25mg
  • Price$245
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD33453
  • Product descriptionN2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine
  • Packaging10mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD33453
  • Product descriptionN2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine
  • Packaging25mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD33453
  • Product descriptionN2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine
  • Packaging50mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD33453
  • Product descriptionN2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine
  • Packaging100mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD33453
  • Product descriptionN2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine
  • Packaging250mg
  • Price$1375
  • Updated2021-12-16
  • Buy
  • ManufacturerBroadPharm
  • Product numberBP-23648
  • Product descriptionDM1 98%
  • Packaging50mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22483
  • Product descriptionMertansine ≥98%
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22483
  • Product descriptionMertansine ≥98%
  • Packaging10mg
  • Price$166
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22483
  • Product descriptionMertansine ≥98%
  • Packaging25mg
  • Price$365
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5804
  • Product descriptionMertansine 99.80%
  • Packaging2mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5804
  • Product descriptionMertansine 99.80%
  • Packaging5mg
  • Price$106
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5804
  • Product descriptionMertansine 99.80%
  • Packaging10mg
  • Price$180
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5584 Mertansine 100mg $1296 2021-12-16 Buy
AvaChem 3948 Mertansine 5mg $85 2021-12-16 Buy
AvaChem 3948 Mertansine 10mg $145 2021-12-16 Buy
AvaChem 3948 Mertansine 25mg $245 2021-12-16 Buy
Biosynth Carbosynth FD33453 N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine 10mg $90 2021-12-16 Buy
Biosynth Carbosynth FD33453 N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine 25mg $200 2021-12-16 Buy
Biosynth Carbosynth FD33453 N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine 50mg $350 2021-12-16 Buy
Biosynth Carbosynth FD33453 N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine 100mg $600 2021-12-16 Buy
Biosynth Carbosynth FD33453 N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine 250mg $1375 2021-12-16 Buy
BroadPharm BP-23648 DM1 98% 50mg $350 2021-12-16 Buy
Cayman Chemical 22483 Mertansine ≥98% 5mg $93 2024-03-01 Buy
Cayman Chemical 22483 Mertansine ≥98% 10mg $166 2024-03-01 Buy
Cayman Chemical 22483 Mertansine ≥98% 25mg $365 2024-03-01 Buy
ChemScene CS-5804 Mertansine 99.80% 2mg $66 2021-12-16 Buy
ChemScene CS-5804 Mertansine 99.80% 5mg $106 2021-12-16 Buy
ChemScene CS-5804 Mertansine 99.80% 10mg $180 2021-12-16 Buy

Properties

Melting point :190-192℃ (decomposition)
Boiling point :937.1±65.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO:60.0(Max Conc. mg/mL);81.26(Max Conc. mM)
form :A crystalline solid
pka :9.82±0.70(Predicted)
color :White to light yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H310 Fatal in contact with skin Acute toxicity,dermal Category 1, 2 Danger GHS hazard pictograms P262, P264, P270, P280, P302+P350,P310, P322, P361, P363, P405, P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger GHS hazard pictograms
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302+P350 IF ON SKIN: Gently wash with plenty of soap and water.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P307+P311 IF exposed: call a POISON CENTER or doctor/physician.
P310 Immediately call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label).
P322 Specific measures (see …on this label).
P330 Rinse mouth.
P361 Remove/Take off immediately all contaminated clothing.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Maytansine, a natural alkaloid, was first isolated from Maydens ovale in 1972 and exists in the genus Maydens of the family Weedaceae and its relatives. The mechanism of action of maytansine, acting on microtubules and tubulin, blocks the formation of spindles in the process of cell mitosis by inhibiting the depolymerization of cell microtubules, and has a strong ability to inhibit tumor cell proliferation.

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