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ChemicalBook >> CAS DataBase List >> Floxuridine

Floxuridine

Floxuridine price.
  • $6 - $8960
  • Product name: Floxuridine
  • CAS: 50-91-9
  • MF: C9H11FN2O5
  • MW: 246.19
  • EINECS:200-072-5
  • MDL Number:MFCD00006530
  • Synonyms:5-FDU;5-FLOXURIDINE;5-FLUORO-1-((2R,4S,5R)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-1H-PYRIMIDINE-2,4-DIONE;5-FLUORO-2'-DEOXY-BETA-URIDINE;(+)-5-FLUORO-2'-DEOXYURIDINE;5-FLUORO-2'-DEOXYURIDINE;2-DEOXY-5'-FLUOROURIDINE;1-(2-DEOXY-BETA-D-RIBOFURANOSYL)-5-FLUOROURACIL
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  • AK Scientific
  • Alfa Aesar
  • ApexBio Technology
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  • ChemScene
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  • ManufacturerAK Scientific
  • Product numberM455
  • Product descriptionFloxuridine
  • Packaging1g
  • Price$21
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberL16497
  • Product description5-Fluoro-2'-deoxyuridine, 98+%
  • Packaging100mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberL16497
  • Product description5-Fluoro-2'-deoxyuridine, 98+%
  • Packaging500mg
  • Price$375
  • Updated2024-03-01
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2402
  • Product descriptionFloxuridine
  • Packaging25mg
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2402
  • Product descriptionFloxuridine
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2402
  • Product descriptionFloxuridine
  • Packaging100mg
  • Price$94
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC3740
  • Product description5-Fluoro-2?-deoxyuridine 99%
  • Packaging1g
  • Price$23
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC3740
  • Product description5-Fluoro-2?-deoxyuridine 99%
  • Packaging5g
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC3740
  • Product description5-Fluoro-2?-deoxyuridine 99%
  • Packaging25g
  • Price$175
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS017523
  • Product descriptionFloxuridine ≥98%
  • Packaging250mg
  • Price$6
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS017523
  • Product descriptionFloxuridine ≥98%
  • Packaging1g
  • Price$13
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS017523
  • Product descriptionFloxuridine ≥98%
  • Packaging5g
  • Price$44
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS017523
  • Product descriptionFloxuridine ≥98%
  • Packaging10g
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS017523
  • Product descriptionFloxuridine ≥98%
  • Packaging25g
  • Price$152
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS017523
  • Product descriptionFloxuridine ≥98%
  • Packaging100g
  • Price$371
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberND02921
  • Product description2'-Deoxy-5-fluorouridine
  • Packaging2g
  • Price$44
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific M455 Floxuridine 1g $21 2021-12-16 Buy
Alfa Aesar L16497 5-Fluoro-2'-deoxyuridine, 98+% 100mg $116 2024-03-01 Buy
Alfa Aesar L16497 5-Fluoro-2'-deoxyuridine, 98+% 500mg $375 2024-03-01 Buy
ApexBio Technology A2402 Floxuridine 25mg $37 2021-12-16 Buy
ApexBio Technology A2402 Floxuridine 10mM(in 1mL DMSO) $60 2021-12-16 Buy
ApexBio Technology A2402 Floxuridine 100mg $94 2021-12-16 Buy
Apolloscientific PC3740 5-Fluoro-2?-deoxyuridine 99% 1g $23 2021-12-16 Buy
Apolloscientific PC3740 5-Fluoro-2?-deoxyuridine 99% 5g $50 2021-12-16 Buy
Apolloscientific PC3740 5-Fluoro-2?-deoxyuridine 99% 25g $175 2021-12-16 Buy
Arctom AS017523 Floxuridine ≥98% 250mg $6 2021-12-16 Buy
Arctom AS017523 Floxuridine ≥98% 1g $13 2021-12-16 Buy
Arctom AS017523 Floxuridine ≥98% 5g $44 2021-12-16 Buy
Arctom AS017523 Floxuridine ≥98% 10g $76 2021-12-16 Buy
Arctom AS017523 Floxuridine ≥98% 25g $152 2021-12-16 Buy
Arctom AS017523 Floxuridine ≥98% 100g $371 2021-12-16 Buy
Biosynth Carbosynth ND02921 2'-Deoxy-5-fluorouridine 2g $44 2021-12-16 Buy

Properties

Melting point :148 °C(lit.)
Boiling point :150 °C
alpha :35.9 º (c=1, water)
Density :1.3751 (estimate)
storage temp. :room temp
solubility :Soluble to 100 mM in water and to 100 mM in DMSO
pka :pKa 7.44 (Uncertain)
form :Powder
color :White to almost white
Water Solubility :soluble
Merck :14,4112
BRN :2645818
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :ODKNJVUHOIMIIZ-GFCOJPQKSA-N
CAS DataBase Reference :50-91-9(CAS DataBase Reference)
NIST Chemistry Reference :Uridine, 2'-deoxy-5-fluoro-(50-91-9)
EPA Substance Registry System :Floxuridine (50-91-9)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Floxuridine is a prodrug that is rapidly catabolized in vivo to 5-fluorouracil when administered by rapid injection. In addition, floxuridine inhibits thymidylate synthase (EC50 = 0.6 nM), interfering with DNA synthesis. It has been used to treat various cancers, particularly metastases to the liver.

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