Floxuridine
Catalog No.
A2402
Antineoplastic antimetabolite
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Antineoplastic antimetabolite. Exhibits antiproliferative activity; inhibits thymidylate synthetase and disrupts DNA replication in human cells. Induces double-strand DNA breaks; activates ATR and ATM signaling pathways. Induces phosphorylation of Chk1 an
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 246.19 |
| Cas No. | 50-91-9 |
| Formula | C9H11FN2O5 |
| Solubility | ≥12.31 mg/mL in DMSO; ≥19.53 mg/mL in EtOH; ≥85.5 mg/mL in H2O |
| Chemical Name | 5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
| SDF | Download SDF |
| Canonical SMILES | C1C(C(OC1N2C=C(C(=O)NC2=O)F)CO)O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
