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ChemicalBook >> CAS DataBase List >> 5-Fluorouracil

5-Fluorouracil

5-Fluorouracil price.
  • $5 - $2492.67
  • Product name: 5-Fluorouracil
  • CAS: 51-21-8
  • MF: C4H3FN2O2
  • MW: 130.08
  • EINECS:200-085-6
  • MDL Number:MFCD00006018
  • Synonyms:2,4(1H,3H)-Pyrimidinedione, 5-fluoro-;2,4-dioxo-5-fluoropyrimidine ;3h)-pyrimidinedione,5-fluoro-4(1h ;5-faracil ;fluoro-uracile ;fluoro-uracilo ;fluorouracilum ;Fluracilum
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  • ManufacturerAHH
  • Product numberMT-13743
  • Product description5-Fluorouracil 98%
  • Packaging1000g
  • Price$798
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ92559
  • Product description5-Fluorouracil
  • Packaging5g
  • Price$10
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberA13456
  • Product description5-Fluorouracil, 99%
  • Packaging5g
  • Price$95.9
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberA13456
  • Product description5-Fluorouracil, 99%
  • Packaging25g
  • Price$355
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberA13456
  • Product description5-Fluorouracil, 99%
  • Packaging100g
  • Price$1046.65
  • Updated2024-03-01
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  • ManufacturerApexBio Technology
  • Product numberA4071
  • Product descriptionFluorouracil(Adrucil)
  • Packaging1g
  • Price$42
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberPC4380
  • Product description5-Fluorouracil 99%
  • Packaging25g
  • Price$18
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIF0123
  • Product description5-Fluorouracil
  • Packaging5g
  • Price$24
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberPC4380
  • Product description5-Fluorouracil 99%
  • Packaging100g
  • Price$55
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIF0123
  • Product description5-Fluorouracil
  • Packaging25g
  • Price$70
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  • Product numberBIF0123
  • Product description5-Fluorouracil
  • Packaging50g
  • Price$122
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS025471
  • Product description5-Fluorouracil ≥98%
  • Packaging5g
  • Price$5
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS025471
  • Product description5-Fluorouracil ≥98%
  • Packaging10g
  • Price$8
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS025471
  • Product description5-Fluorouracil ≥98%
  • Packaging25g
  • Price$15
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberCFN60175
  • Product descriptionFluorouracil
  • Packaging20mg
  • Price$30
  • Updated2021-12-16
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  • ManufacturerAstaTech
  • Product number28568
  • Product description5-Fluorouracil 95%
  • Packaging5/ G
  • Price$30
  • Updated2021-12-16
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Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-13743 5-Fluorouracil 98% 1000g $798 2021-12-16 Buy
AK Scientific J92559 5-Fluorouracil 5g $10 2021-12-16 Buy
Alfa Aesar A13456 5-Fluorouracil, 99% 5g $95.9 2024-03-01 Buy
Alfa Aesar A13456 5-Fluorouracil, 99% 25g $355 2024-03-01 Buy
Alfa Aesar A13456 5-Fluorouracil, 99% 100g $1046.65 2024-03-01 Buy
ApexBio Technology A4071 Fluorouracil(Adrucil) 1g $42 2021-12-16 Buy
Apolloscientific PC4380 5-Fluorouracil 99% 25g $18 2021-12-16 Buy
Apolloscientific BIF0123 5-Fluorouracil 5g $24 2021-12-16 Buy
Apolloscientific PC4380 5-Fluorouracil 99% 100g $55 2021-12-16 Buy
Apolloscientific BIF0123 5-Fluorouracil 25g $70 2021-12-16 Buy
Apolloscientific BIF0123 5-Fluorouracil 50g $122 2021-12-16 Buy
Arctom AS025471 5-Fluorouracil ≥98% 5g $5 2021-12-16 Buy
Arctom AS025471 5-Fluorouracil ≥98% 10g $8 2021-12-16 Buy
Arctom AS025471 5-Fluorouracil ≥98% 25g $15 2021-12-16 Buy
Arctom CFN60175 Fluorouracil 20mg $30 2021-12-16 Buy
AstaTech 28568 5-Fluorouracil 95% 5/ G $30 2021-12-16 Buy

Properties

Melting point :282-286 °C (dec.) (lit.)
Boiling point :190-200°C/0.1mmHg
Density :1.4593 (estimate)
storage temp. :2-8°C
solubility :H2O: 10 mg/mL, clear
form :powder
pka :pKa 8.0±0.1 (H2O) (Uncertain);3.0±0.1(H2O) (Uncertain)
color :white
PH :4.3-5.3 (10g/l, H2O, 20℃)
Water Solubility :12.2 g/L 20 ºC
Sensitive :Air Sensitive
Merck :14,4181
BRN :127172
Stability :Stable. Light sensitive. Combustible. Incompatible with strong oxidizing agents, strong bases.
InChIKey :GHASVSINZRGABV-UHFFFAOYSA-N
CAS DataBase Reference :51-21-8(CAS DataBase Reference)
IARC :3 (Vol. 26, Sup 7) 1987
NIST Chemistry Reference :2,4-Pyrimidinedione, 5-fluoro-(51-21-8)
EPA Substance Registry System :5-Fluorouracil (51-21-8)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

5-Fluorouracil is a pyrimadine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis. Intracellular metabolites of fluorouracil exert cytotoxic effects by either inhibiting thymidylate synthetase, or through incorporation into RNA and DNA, ultimately initiating apoptosis. 5-Fluorouracil has been widely used to treat many gastrointestinal tract adenocarcinomas. However, its clinical application is greatly limited due to drug resistance.

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