Finasteride
|
- $26 - $845
- Product name: Finasteride
- CAS: 98319-26-7
- MF: C23H36N2O2
- MW: 372.54
- EINECS:620-534-3
- MDL Number:MFCD00869737
- Synonyms:(5alpha,17beta)-(1,1-dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide ;17beta-(n-tert-butylcarbamoyl)-4-aza-5alpha-androst-1-en-3-one ;4-azaandrost-1-ene-17-carboxamide,n-(1,1-dimethylethyl)-3-oxo-,(5-alpha,17-be ;4-azaandrost-1-ene-17-carboxamide,n-(1,1-dimethylethyl)-3-oxo-,(5alpha,17beta ;l-652,931 ;mk-0906 ;(5alpha,17beta)-N-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide;(5α，17β)-N-(1，1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide
41 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Alfa Aesar
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 10mg
- 50mg
- 100mg
- y0000090
- 25mg
- 50
- y0001604
- 200mg
- 250mg
- 500mg
- 10g
- 25g
- 1g
- 5g
- 10mM(in 1mL DMSO)
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3589-M100
- Product descriptionFinasteride ≥98%(HPLC)
- Packaging100mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ10122
- Product descriptionFinasteride
- Packaging100mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberH045
- Product descriptionFinasteride
- Packaging250mg
- Price$67
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberH045
- Product descriptionFinasteride
- Packaging25g
- Price$554
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ63454
- Product descriptionFinasteride
- Packaging100mg
- Price$62.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ63454
- Product descriptionFinasteride
- Packaging500mg
- Price$121.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ63454
- Product descriptionFinasteride
- Packaging1g
- Price$192.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ63454
- Product descriptionFinasteride
- Packaging5g
- Price$741.65
- Updated2024-03-01
- Buy
- ManufacturerApexBio Technology
- Product numberA5143
- Product descriptionFinasteride
- Packaging100mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5143
- Product descriptionFinasteride
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5143
- Product descriptionFinasteride
- Packaging200mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS474989
- Product descriptionFinasteride ≥98%
- Packaging250mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS474989
- Product descriptionFinasteride ≥98%
- Packaging100mg
- Price$58
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS474989
- Product descriptionFinasteride ≥98%
- Packaging25mg
- Price$26
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2254
- Product descriptionFinasteride
- Packaging100mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2254
- Product descriptionFinasteride
- Packaging1g
- Price$109
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-3589-M100 | Finasteride ≥98%(HPLC) | 100mg | $45 | 2021-12-16 | Buy |
| AK Scientific | J10122 | Finasteride | 100mg | $60 | 2021-12-16 | Buy |
| AK Scientific | H045 | Finasteride | 250mg | $67 | 2021-12-16 | Buy |
| AK Scientific | H045 | Finasteride | 25g | $554 | 2021-12-16 | Buy |
| Alfa Aesar | J63454 | Finasteride | 100mg | $62.65 | 2024-03-01 | Buy |
| Alfa Aesar | J63454 | Finasteride | 500mg | $121.65 | 2024-03-01 | Buy |
| Alfa Aesar | J63454 | Finasteride | 1g | $192.65 | 2024-03-01 | Buy |
| Alfa Aesar | J63454 | Finasteride | 5g | $741.65 | 2024-03-01 | Buy |
| ApexBio Technology | A5143 | Finasteride | 100mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A5143 | Finasteride | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
| ApexBio Technology | A5143 | Finasteride | 200mg | $80 | 2021-12-16 | Buy |
| Arctom | AS474989 | Finasteride ≥98% | 250mg | $95 | 2021-12-16 | Buy |
| Arctom | AS474989 | Finasteride ≥98% | 100mg | $58 | 2021-12-16 | Buy |
| Arctom | AS474989 | Finasteride ≥98% | 25mg | $26 | 2021-12-16 | Buy |
| AvaChem | 2254 | Finasteride | 100mg | $40 | 2021-12-16 | Buy |
| AvaChem | 2254 | Finasteride | 1g | $109 | 2021-12-16 | Buy |
Properties
Melting point :253 °C
alpha :405 -59° (c = 1 in methanol)
Boiling point :576.6±50.0 °C(Predicted)
Density :1.065±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: 32 mg/mL, soluble
form :solid
pka :14.17±0.70(Predicted)
color :white to beige
Water Solubility :insoluble
Merck :14,4082
BCS Class :1
InChIKey :DBEPLOCGEIEOCV-WSBQPABSSA-N
LogP :3.030
CAS DataBase Reference :98319-26-7(CAS DataBase Reference)
EPA Substance Registry System :1H-Indeno[5,4-f]quinoline-7-carboxamide, N-(1,1-dimethylethyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7S,9aS,9bS,11aR)- (98319-26-7)
alpha :405 -59° (c = 1 in methanol)
Boiling point :576.6±50.0 °C(Predicted)
Density :1.065±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: 32 mg/mL, soluble
form :solid
pka :14.17±0.70(Predicted)
color :white to beige
Water Solubility :insoluble
Merck :14,4082
BCS Class :1
InChIKey :DBEPLOCGEIEOCV-WSBQPABSSA-N
LogP :3.030
CAS DataBase Reference :98319-26-7(CAS DataBase Reference)
EPA Substance Registry System :1H-Indeno[5,4-f]quinoline-7-carboxamide, N-(1,1-dimethylethyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7S,9aS,9bS,11aR)- (98319-26-7)
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
5α-Reductase catalyzes the NADPH-dependent reduction of Δ4,5 double bonds in several steroid substrates, including testosterone, which is converted to dihydrotestosterone, the primary mediator of prostate growth. The 5α-reductase enzymes responsible for the reduction of testosterone to dihydrotestosterone exists as two forms: type I, which occurs in the skin, liver, and ventral prostate and type II, which is expressed in ventral prostate, epididymis, and other reproductive tissues. Finasteride is a 4-azasteroid analog of testosterone that competitively blocks type II 5α-reductase activity (IC50 = 4.2 nM) with 100-fold greater affinity than for the type I enzyme. It has been used in the treatment of benign prostatic hyperplasia, decreasing human prostatic dihydrotestosterone levels by 70-90% and reducing prostatic size. However, at 10 μM finasteride has also been shown to induce the expression of Nrf2 and HO-1 proteins in androgen refractory prostrate PC-3 cells, which has been implicated in increased high-grade prostate tumor formation. Also, at 0.1 μM finasteride can inhibit testosterone-induced type I procollagen and TGF-β1 expression in human scalp dermal fibroblasts in a model of androgenic alopecia.Related product price
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Suppliers and manufacturers
Shaanxi Pioneer Biotech Co., Ltd .
Shaanxi Xianhe Biotech Co., Ltd
