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ChemicalBook >> CAS DataBase List >> AZD-9291

AZD-9291

AZD-9291 price.
  • $32 - $988
  • Product name: AZD-9291
  • CAS: 1421373-65-0
  • MF: C28H33N7O2
  • MW: 499.61
  • EINECS:629-848-5
  • MDL Number:MFCD27988062
  • Synonyms:N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide;Mereletinib mesylate(AZD9291);AZD9291 (free base);Osimertinib (AZD-9291);AZD9291, Osimertinib;AZD9291 Base;Osimertinib Base;AZD9291 10G
35 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 5MG
  • 10mg
  • 20mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 1000mg
  • 2g
  • 10g
  • 10mM(in 1mL DMSO)
  • 5g
  • ManufacturerAK Scientific
  • Product numberJ97812
  • Product descriptionAZD-9291
  • Packaging5g
  • Price$270
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0045869
  • Product descriptionOSIMERTINIB 95.00%
  • Packaging5MG
  • Price$450.51
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1104
  • Product descriptionAZD-9291
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1104
  • Product descriptionAZD-9291
  • Packaging10mM(in 1mL DMSO)
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1104
  • Product descriptionAZD-9291
  • Packaging10mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1104
  • Product descriptionAZD-9291
  • Packaging50mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1104
  • Product descriptionAZD-9291
  • Packaging500mg
  • Price$980
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60119
  • Product descriptionOsimertinib(AZD9291) ≥98%
  • Packaging20mg
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180883
  • Product descriptionMereletinib (AZD-9291,Osimertinib) >98%
  • Packaging100mg
  • Price$397.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180883
  • Product descriptionMereletinib (AZD-9291,Osimertinib) >98%
  • Packaging250mg
  • Price$606.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180883
  • Product descriptionMereletinib (AZD-9291,Osimertinib) >98%
  • Packaging1000mg
  • Price$912.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD58317
  • Product descriptionAZD 9291
  • Packaging10mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD58317
  • Product descriptionAZD 9291
  • Packaging50mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD58317
  • Product descriptionAZD 9291
  • Packaging100mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD58317
  • Product descriptionAZD 9291
  • Packaging250mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD58317
  • Product descriptionAZD 9291
  • Packaging500mg
  • Price$200
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J97812 AZD-9291 5g $270 2021-12-16 Buy
American Custom Chemicals Corporation API0045869 OSIMERTINIB 95.00% 5MG $450.51 2021-12-16 Buy
ApexBio Technology B1104 AZD-9291 5mg $70 2021-12-16 Buy
ApexBio Technology B1104 AZD-9291 10mM(in 1mL DMSO) $90 2021-12-16 Buy
ApexBio Technology B1104 AZD-9291 10mg $95 2021-12-16 Buy
ApexBio Technology B1104 AZD-9291 50mg $250 2021-12-16 Buy
ApexBio Technology B1104 AZD-9291 500mg $980 2021-12-16 Buy
Arctom CFN60119 Osimertinib(AZD9291) ≥98% 20mg $218 2021-12-16 Buy
Biorbyt Ltd orb180883 Mereletinib (AZD-9291,Osimertinib) >98% 100mg $397.8 2021-12-16 Buy
Biorbyt Ltd orb180883 Mereletinib (AZD-9291,Osimertinib) >98% 250mg $606.9 2021-12-16 Buy
Biorbyt Ltd orb180883 Mereletinib (AZD-9291,Osimertinib) >98% 1000mg $912.9 2021-12-16 Buy
Biosynth Carbosynth FD58317 AZD 9291 10mg $65 2021-12-16 Buy
Biosynth Carbosynth FD58317 AZD 9291 50mg $90 2021-12-16 Buy
Biosynth Carbosynth FD58317 AZD 9291 100mg $120 2021-12-16 Buy
Biosynth Carbosynth FD58317 AZD 9291 250mg $150 2021-12-16 Buy
Biosynth Carbosynth FD58317 AZD 9291 500mg $200 2021-12-16 Buy

Properties

Melting point :>188oC (dec.)
Density :1.19±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly, Heated), Methanol (Slightly, Heated)
pka :12.68±0.70(Predicted)
form :Solid
color :Pale Yellow to Beige
CAS DataBase Reference :1421373-65-0

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

AZD-9291 (Mesylate), also known as Osimertinib, belongs to a third-generation EGFR (epidermal growth factor receptor) inhibitor. It can be used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) in case when the cancer cells carry specific mutations (such as T790M) in the epidermal growth factor receptor. It takes effect through directly binding to the certain mutant forms of EGFR (T790M, L858R, and exon 19 deletions) that are frequently found in NSCLC, further causing poor prognosis for late-stage disease. Since it spares wild type EGFR during therapy, it has only limited toxicity.