Bisindolylmaleimide VIII acetate salt

$45 - $478
Product name: Bisindolylmaleimide VIII acetate salt
CAS: 138516-31-1
MF: C24H22N4O2
MW: 398.464
EINECS:
MDL Number:MFCD00909467
Synonyms:BisindolylMaleiMide VIII . AcOH [Ro 31-7549];BISINDOLYLMALEIMIDE VIII ACETATE SALT;RO 31-7549 ACETATE;3-[1-(3-Aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione monoacetate;Bis VIII acetate;1H-Pyrrole-2,5-dione, 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-, acetate (1:1);protein,Bisindolylmaleimide VIII acetate,Ro 31-7549,Inhibitor,inhibit,Fas,Bis VIII,Apoptosis,autoimmune,Protein kinase C,diseases,kinase,cell-mediated,Bisindolylmaleimide VIII,PKC;3-(1-(3-Aminopropyl)-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione acetate

Price11 Properties Safety Information Description

11 prices

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Brand

Adipogen Life Sciences
AK Scientific
ApexBio Technology
Cayman Chemical
ChemScene
TRC

Package

1mg
5mg
10mg

ManufacturerAdipogen Life Sciences
Product numberAG-CR1-0114-M001
Product descriptionBisindolylmaleimideVIII.acetate ≥98%(NMR)
Packaging1mg
Price$45
Updated2021-12-16
Buy

ManufacturerAdipogen Life Sciences
Product numberAG-CR1-0114-M005
Product descriptionBisindolylmaleimideVIII.acetate ≥98%(NMR)
Packaging5mg
Price$170
Updated2021-12-16
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ManufacturerAK Scientific
Product number3821CR
Product descriptionBisindolylmaleimideVIII
Packaging10mg
Price$478
Updated2021-12-16
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ManufacturerAK Scientific
Product number3821CR
Product descriptionBisindolylmaleimideVIII
Packaging5mg
Price$301
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberC4315
Product descriptionBisindolylmaleimideVIII(acetate)
Packaging5mg
Price$207
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberC4315
Product descriptionBisindolylmaleimideVIII(acetate)
Packaging10mg
Price$389
Updated2021-12-16
Buy

ManufacturerCayman Chemical
Product number13333
Product descriptionBisindolylmaleimide VIII (acetate) ≥98%
Packaging1mg
Price$50
Updated2024-03-01
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ManufacturerCayman Chemical
Product number13333
Product descriptionBisindolylmaleimide VIII (acetate) ≥98%
Packaging5mg
Price$183
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number13333
Product descriptionBisindolylmaleimide VIII (acetate) ≥98%
Packaging10mg
Price$341
Updated2024-03-01
Buy

ManufacturerChemScene
Product numberCS-0115630
Product descriptionBisindolylmaleimideVIII(acetate)
Packaging5mg
Price$260
Updated2021-12-16
Buy

ManufacturerTRC
Product numberB448500
Product descriptionBisindolylmaleimideVIIIAceticAcidSalt
Packaging10mg
Price$175
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
Adipogen Life Sciences	AG-CR1-0114-M001	BisindolylmaleimideVIII.acetate ≥98%(NMR)	1mg	$45	2021-12-16	Buy
Adipogen Life Sciences	AG-CR1-0114-M005	BisindolylmaleimideVIII.acetate ≥98%(NMR)	5mg	$170	2021-12-16	Buy
AK Scientific	3821CR	BisindolylmaleimideVIII	10mg	$478	2021-12-16	Buy
AK Scientific	3821CR	BisindolylmaleimideVIII	5mg	$301	2021-12-16	Buy
ApexBio Technology	C4315	BisindolylmaleimideVIII(acetate)	5mg	$207	2021-12-16	Buy
ApexBio Technology	C4315	BisindolylmaleimideVIII(acetate)	10mg	$389	2021-12-16	Buy
Cayman Chemical	13333	Bisindolylmaleimide VIII (acetate) ≥98%	1mg	$50	2024-03-01	Buy
Cayman Chemical	13333	Bisindolylmaleimide VIII (acetate) ≥98%	5mg	$183	2024-03-01	Buy
Cayman Chemical	13333	Bisindolylmaleimide VIII (acetate) ≥98%	10mg	$341	2024-03-01	Buy
ChemScene	CS-0115630	BisindolylmaleimideVIII(acetate)	5mg	$260	2021-12-16	Buy
TRC	B448500	BisindolylmaleimideVIIIAceticAcidSalt	10mg	$175	2021-12-16	Buy

Properties

storage temp. :-20°C
solubility :Soluble in DMSO
form :Red powder.
color :Brown to reddish brown

Safety Information

Symbol(GHS):

Signal word:

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes

Precautionary statements:

Description

Bisindolylmaleimide VIII (BIM VIII) is a selective protein kinase C (PKC) inhibitor (IC50 = 158 nM for rat brain PKC) that acts at the ATP binding site of PKC. This compound exhibits some degree of PKC isozyme specificity with preference for PKCα over PKCβI, PKCβII, PKCγ, or PKCε (IC50s = 53, 195, 163, 213, and 175 nM, respectively). At 10 μM BIM VIII does not inhibit the tyrosine phosphorylation or the activation of phospholipase C γ1. BIM VIII inhibits carbachol-evoked noradrenaline release from human SH-SY5Y neuroblastoma cells with an IC50 value of 600 nM.

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