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ChemicalBook >> CAS DataBase List >> K-252B

K-252B

K-252B price.
  • $173.4 - $3200
  • Product name: K-252B
  • CAS: 99570-78-2
  • MF: C26H19N3O5
  • MW: 453.45
  • EINECS:999-999-2
  • MDL Number:MFCD09878299
  • Synonyms:PROTEIN KINASE INHIBITOR K-252B;K-252B;K-252B, NOCARDIOPSIS SP;K-252B, NOCARDIOPSIS SPECIES;K252B READY MADE;k-252b solution;Antibiotic K 252b;KT 5556
6 prices
Selected condition:
Brand
  • Biorbyt Ltd
  • Cayman Chemical
  • Medical Isotopes, Inc.
  • TRC
Package
  • 100μg
  • 500μg
  • 1mg
  • 2.5mg
  • ManufacturerBiorbyt Ltd
  • Product numberorb545968
  • Product descriptionK252b >98%
  • Packaging100μg
  • Price$173.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545968
  • Product descriptionK252b >98%
  • Packaging1mg
  • Price$554.2
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11339
  • Product descriptionK252b ≥98%
  • Packaging500μg
  • Price$195
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11339
  • Product descriptionK252b ≥98%
  • Packaging1mg
  • Price$335
  • Updated2024-03-01
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number65721
  • Product descriptionK252b
  • Packaging2.5mg
  • Price$3200
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberK000505
  • Product descriptionK252b
  • Packaging2.5mg
  • Price$2180
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Biorbyt Ltd orb545968 K252b >98% 100μg $173.4 2021-12-16 Buy
Biorbyt Ltd orb545968 K252b >98% 1mg $554.2 2021-12-16 Buy
Cayman Chemical 11339 K252b ≥98% 500μg $195 2024-03-01 Buy
Cayman Chemical 11339 K252b ≥98% 1mg $335 2024-03-01 Buy
Medical Isotopes, Inc. 65721 K252b 2.5mg $3200 2021-12-16 Buy
TRC K000505 K252b 2.5mg $2180 2021-12-16 Buy

Properties

Boiling point :769.8±60.0 °C(Predicted)
Density :1.78±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :Soluble in DMSO (up to 1 mg/ml) or in DMF (up to 1 mg/ml).
form :ready-to-use solution
pka :3.33±0.40(Predicted)
color :White or off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

K252b is an indolocarbazole isolated from the actinomycete Nocardiopsis, first described as an inhibitor of protein kinase C. However, as this compound does not freely pass through the cell membrane, it is used to inhibit extracellular kinases (ectokinases) of cells in culture. K252b inhibits receptor-mediated degranulation from basophil-like RBL-2H3 cells (IC50 = 0.5 μg/ml) and human basophils. This extracellular inhibitor is also used in comparison studies with the closely related, cell-permeable inhibitor K252a, particularly in studies of neuronal differentiation.

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