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ChemicalBook >> CAS DataBase List >> Phloretin

Phloretin

Phloretin price.
  • $6 - $2055.9
  • Product name: Phloretin
  • CAS: 60-82-2
  • MF: C15H14O5
  • MW: 274.27
  • EINECS:200-488-7
  • MDL Number:MFCD00002288
  • Synonyms:2,4,6-Trihydroxy-B-(4-Hydroxyphenyl)Propiophenone;Phloretin,98%;β-(4-hydroxyphenyl)-2,4,6-trihydroxypropiophenone;PHLORETIN(RG);1-Propanone, 3-(4-hydroxyphenyl)-1-(2,4,6-;trihydroxyphenyl)-;β-(4-Hydroxyphenyl)-2,4,6-trihydroxypropiophenone, 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone, 2μ,4μ,6μ-Trihydroxy-3-(4-hydroxyphenyl)propiophenone;2',4,4',6'-Tetrahydroxy-α,β-dihydro-trans-chalcone
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Brand
  • AHH
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • JR MediChem
  • Labseeker
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • SynQuest Laboratories
  • TCI Chemical
  • TRC
  • Usbiological
Package
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  • 10mM(in 1mL DMSO)
  • 250mg
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  • 1G
  • 5g
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  • 25g
  • 50g
  • 100g
  • ManufacturerAHH
  • Product numberMT-57942
  • Product descriptionPhloretin 98%
  • Packaging5g
  • Price$560
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ90074
  • Product descriptionPhloretin
  • Packaging10g
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberL10991
  • Product descriptionPhloretin, 98%
  • Packaging25mg
  • Price$31.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberL10991
  • Product descriptionPhloretin, 98%
  • Packaging100mg
  • Price$73.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA170374
  • Product description3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one 98+%
  • Packaging250mg
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA170374
  • Product description3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one 98+%
  • Packaging5g
  • Price$24
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA170374
  • Product description3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one 98+%
  • Packaging100g
  • Price$341
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000554
  • Product description2',4',6'-TRIHYDROXY-3-(4-HYDROXYPHENYL)-PROPIOPHENONE 95.00%
  • Packaging5MG
  • Price$535.45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000554
  • Product description2',4',6'-TRIHYDROXY-3-(4-HYDROXYPHENYL)-PROPIOPHENONE 95.00%
  • Packaging1G
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000554
  • Product description2',4',6'-TRIHYDROXY-3-(4-HYDROXYPHENYL)-PROPIOPHENONE 95.00%
  • Packaging10G
  • Price$2055.9
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3723
  • Product descriptionPhloretin
  • Packaging500mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3723
  • Product descriptionPhloretin
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN97040
  • Product descriptionPhloretin ≥98%
  • Packaging20mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3282
  • Product descriptionPhloretin
  • Packaging25mg
  • Price$29
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number3282
  • Product descriptionPhloretin
  • Packaging100mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3282
  • Product descriptionPhloretin
  • Packaging250mg
  • Price$49
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-57942 Phloretin 98% 5g $560 2021-12-16 Buy
AK Scientific J90074 Phloretin 10g $65 2021-12-16 Buy
Alfa Aesar L10991 Phloretin, 98% 25mg $31.65 2024-03-01 Buy
Alfa Aesar L10991 Phloretin, 98% 100mg $73.65 2024-03-01 Buy
Ambeed A170374 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one 98+% 250mg $6 2021-12-16 Buy
Ambeed A170374 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one 98+% 5g $24 2021-12-16 Buy
Ambeed A170374 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one 98+% 100g $341 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000554 2',4',6'-TRIHYDROXY-3-(4-HYDROXYPHENYL)-PROPIOPHENONE 95.00% 5MG $535.45 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000554 2',4',6'-TRIHYDROXY-3-(4-HYDROXYPHENYL)-PROPIOPHENONE 95.00% 1G $704.55 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000554 2',4',6'-TRIHYDROXY-3-(4-HYDROXYPHENYL)-PROPIOPHENONE 95.00% 10G $2055.9 2021-12-16 Buy
ApexBio Technology A3723 Phloretin 500mg $50 2021-12-16 Buy
ApexBio Technology A3723 Phloretin 10mM(in 1mL DMSO) $50 2021-12-16 Buy
Arctom CFN97040 Phloretin ≥98% 20mg $40 2021-12-16 Buy
AvaChem 3282 Phloretin 25mg $29 2021-12-16 Buy
AvaChem 3282 Phloretin 100mg $39 2021-12-16 Buy
AvaChem 3282 Phloretin 250mg $49 2021-12-16 Buy

Properties

Melting point :~260 °C
Boiling point :337.26°C (rough estimate)
Density :1.1827 (rough estimate)
FEMA :4390 | 3-(4-HYDROXYPHENYL)-1-(2,4,6-TRIHYDROXYPHENYL)PROPAN-1-ONE
refractive index :1.573-1.575
storage temp. :2-8°C
solubility :Acetonitrile (Slightly), Methanol (Slightly)
pka :7.16±0.40(Predicted)
form :Powder
color :White to beige
Odor :odorless
Water Solubility :soluble
Merck :14,7326
JECFA Number :2022
BRN :1887240
InChIKey :VGEREEWJJVICBM-UHFFFAOYSA-N
LogP :3.50
CAS DataBase Reference :60-82-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Phloretin is a natural phenol which inhibits a variety of transporters. It inhibits the monocarboxylate transporters MCT1 and MCT2 (IC50 = 28 and 14 μM, respectively), restricting the rapid transport of monocarboxylates like lactate and pyruvate across the plasma membrane. Phloretin also blocks the sodium/D-glucose cotransporter (Ki = 86 μM) and the human concentrative nucleoside transporter 3 (Ki = 32 μM).

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