ChemicalBook >?? ???? >9-??????
9-??????
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9-?????? ??
- ???
- 184°C
- ?? ?
- 388.54°C (rough estimate)
- ??
- 0.9418 (rough estimate)
- ???
- 1.6500 (estimate)
- ?? ??
- Sealed in dry,Room Temperature
- ?? ?? (pKa)
- 5.45±0.10(Predicted)
- ??? ??
- powder to crystal
- ??
- Light yellow to Amber to Dark green
- InChI
- InChI=1S/C19H13N/c1-2-8-14(9-3-1)19-15-10-4-6-12-17(15)20-18-13-7-5-11-16(18)19/h1-13H
- InChIKey
- MTRFEWTWIPAXLG-UHFFFAOYSA-N
- SMILES
- C1C2C(=NC3C(C=2C2=CC=CC=C2)=CC=CC=3)C=CC=1
- CAS ??????
- 602-56-2(CAS DataBase Reference)
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ????? | 22-24/25 | ||
|---|---|---|---|
| HS ?? | 2933.99.8210 | ||
| ???? ?? | 2012-1-631 | ||
| ?????? ??? | 2012-1-631 | ||
| ?? ? ???? | ????: ????; ???(??)????: 9-?????? ? ?? 25% ?? ??? ??? |
| ????(GHS): |
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9-?????? C??? ??, ??, ??
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Research has found that 9-phenylacridine (ACPH) exhibited anticancer activity in cell lines and in vivo animal models. Bioinformatics studies have indicated that it could have topoisomerase I inhibitory activity. It could also act as a PARP 1 inhibitor and was very effective in combination with cisplatin in cell line-based assays. ACPH also satisfied all criteria for a candidate drug from the Lipinski rule and showed good cell uptake. ACPH alone was effective in the A375 melanoma cell line. ACPH could be used as a promising new photosensitizer[1-2]. 9-Phenylacridine is the parent base of chrysaniline or 3,6-diamino-9- phenylacridine, the chief constituent of the dyestuff phosphine. It is commonly used in the electronics industry as a free radical photoinitiator, significantly improving photo speed.??
9-Phenylacridine has antitumour activity. It can be used as a photosensitiser and can sensitise UVA-induced DNA damage in vitro and in cells. It also enhances cell killing by UVA. In addition. It is also used in photochemical research and as a raw material for organic synthesis.9-?????? ?? ?? ? ???
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Acridine, 1,2,3,4-tetrahydro-9-phenyl-
9-??-9,10-????????
Benzonitrile, 2-(phenylamino)-
Methanone, phenyl[2-(phenylamino)phenyl]-
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9-???????
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2-??????-1-?
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9-?????? ?? ??
???( 187)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
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9-?????? ?? ??:
C.I. ?? VI?ET 19 9-??????
9(10H)-ACRIDONE
Basic Orange 14
6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE
Amsacrine hydrochloride
2-ETHOXY-6,9-DIAMINOACRIDINE
10-METHYL-9-PHENYLACRIDINIUM PERCHLORATE
CI 46045
9-(2,6-DIMETHYLPHENYL)-10-METHYLACRIDINIUM PERCHLORATE
9-(2-BIPHENYLYL)-10-METHYLACRIDINIUM PERCHLORATE
BENZOFLAVIN
9-(2,5-DIMETHYLPHENYL)-10-METHYLACRIDINIUM PERCHLORATE
9-MESITYL-10-METHYLACRIDINIUM PERCHLORATE
PHOSPHINE E
9,10-Dihydro-9-phenylacridine
4-(9-Acridinyl)-N,N-dimethylaniline
2-chloro-9-phenylacridine