9-Phenylacridin
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- CAS-Nr.
- 602-56-2
- Bezeichnung:
- 9-Phenylacridin
- Englisch Name:
- 9-Phenylacridine
- Synonyma:
- 9-PA;phenylacridine;9-phenyl-acridin;9-PHENYLACRIDINE;Acridine, 9-phenyl-;9-Phenylacridine>9-Phenylacridin (9-PA);3-propan-2-yloxy-1-cyclohex-2-enone;TIANFU-CHEM CAS:602-56-2 9-Phenylacridine
- CBNumber:
- CB9478127
- Summenformel:
- C19H13N
- Molgewicht:
- 255.31
- MOL-Datei:
- 602-56-2.mol
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9-Phenylacridin Eigenschaften
- Schmelzpunkt:
- 184°C
- Siedepunkt:
- 388.54°C (rough estimate)
- Dichte
- 0.9418 (rough estimate)
- Brechungsindex
- 1.6500 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- Aggregatzustand
- powder to crystal
- pka
- 5.45±0.10(Predicted)
- Farbe
- Light yellow to Amber to Dark green
- InChI
- InChI=1S/C19H13N/c1-2-8-14(9-3-1)19-15-10-4-6-12-17(15)20-18-13-7-5-11-16(18)19/h1-13H
- InChIKey
- MTRFEWTWIPAXLG-UHFFFAOYSA-N
- SMILES
- C1C2C(=NC3C(C=2C2=CC=CC=C2)=CC=CC=3)C=CC=1
- CAS Datenbank
- 602-56-2(CAS DataBase Reference)
- NIST chemische Informationen
- Acridine, 9-phenyl-(602-56-2)
- EPA chemische Informationen
- Acridine, 9-phenyl- (602-56-2)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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9-Phenylacridin Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Verwenden
Research has found that 9-phenylacridine (ACPH) exhibited anticancer activity in cell lines and in vivo animal models. Bioinformatics studies have indicated that it could have topoisomerase I inhibitory activity. It could also act as a PARP 1 inhibitor and was very effective in combination with cisplatin in cell line-based assays. ACPH also satisfied all criteria for a candidate drug from the Lipinski rule and showed good cell uptake. ACPH alone was effective in the A375 melanoma cell line. ACPH could be used as a promising new photosensitizer[1-2]. 9-Phenylacridine is the parent base of chrysaniline or 3,6-diamino-9- phenylacridine, the chief constituent of the dyestuff phosphine. It is commonly used in the electronics industry as a free radical photoinitiator, significantly improving photo speed.
Beschreibung
9-Phenylacridine has antitumour activity. It can be used as a photosensitiser and can sensitise UVA-induced DNA damage in vitro and in cells. It also enhances cell killing by UVA. In addition. It is also used in photochemical research and as a raw material for organic synthesis.
9-Phenylacridin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
9-Phenylacridin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 187)Lieferanten
602-56-2(9-Phenylacridin)Verwandte Suche:
- 9-phenyl-acridin
- phenylacridine
- 9-PHENYLACRIDINE
- Acridine, 9-phenyl-
- 9-Phenylacridin (9-PA)
- 3-propan-2-yloxy-1-cyclohex-2-enone
- 9-PA
- 9-Phenylacridine>
- TIANFU-CHEM CAS:602-56-2 9-Phenylacridine
- 602-56-2
- C19H13N
- Miscellaneous
