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692-29-5
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???(??):
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SUCCINALDEHYDIC ACID
???(??):
SUCCINIC SEMIALDEHYDE;4-oxo-butanoicaci;4-OXOBUTYRIC ACID;butryaldehydicacid;4-OXO-BUTANOIC ACID;gamma-oxybutyricacid;SUCCINALDEHYDIC ACID;3-formylpropionicacid;3-formylpropanoicacid;Butanoic acid, 4-oxo-
CBNumber:
CB5102710
???:
C4H6O3
??? ??:
102.09
MOL ??:
692-29-5.mol

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202-203 °C(Solv: methanol (67-56-1))
?? ?
142-143 °C(Press: 13 Torr)
??
1.09 g/mL at 25 °C
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2-8°C
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DMSO(?? ???), ???(?? ???)
?? ?? (pKa)
4.69±0.17(Predicted)
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  • ?? ? ???? ?? (GHS)
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WGK ?? -
????(GHS): GHS hazard pictograms
?? ?: Warning
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?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P321 (…) ??? ???.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P362 ??? ??? ?? ?? ?? ?????

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β-Formylpropionic Acid is used in the synthesis of potent and orally available nonpeptide antagonist of human gonadotropin-releasing hormone receptor. It is also a reagent in the synthesis of human melanocortin-4 receptor antagonists with a pyrrolidinone moiety.

Synthesis Reference(s)

Tetrahedron Letters, 14, p. 3535, 1973 DOI: 10.1016/S0040-4039(01)86963-X

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Benzamide, N-chloro- ?????? 3-[1,3]????-2-?-????? ??????? 5-??????? 2(5H)-Furanone 4-????? ?????? L-????? DL-????

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??-??????? 3-??????? 5-?????-2[5H]-??? ??????

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