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4-???(1H)???

4-???(1H)???
4-???(1H)??? ??? ???
?? ??:
186407-74-9
???:
4-???(1H)???
???(??):
4-???(1H)???
???:
4-Bromo-1H-indazole
???(??):
4-BROMOINDAZOLE;broMo-1H-indazole;4-Bromoindazole >4-BROMO (1H)INDAZOLE;1H-Indazole, 4-bromo-;4-BroMo-1H-indazole, 97+%;4-bromo-1H-indazole£4-Bromoindazole;186407-74-9
CBNumber:
CB4442606
???:
C7H5BrN2
??? ??:
197.03
MOL ??:
186407-74-9.mol
MSDS ??:
SDS

4-???(1H)??? ??

???
165-167°
?? ?
333.8±15.0 °C(Predicted)
??
1.770±0.06 g/cm3(Predicted)
?? ??
2-8°C
???
???? ???
??? ??
??
??? ??
??? ??
?? ?? (pKa)
12.78±0.40(Predicted)
??
???
InChI
InChI=1S/C7H5BrN2/c8-6-2-1-3-7-5(6)4-9-10-7/h1-4H,(H,9,10)
InChIKey
KJIODOACRIRBPB-UHFFFAOYSA-N
SMILES
N1C2=C(C(Br)=CC=C2)C=N1
CAS ??????
186407-74-9(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi,T
?? ???? ?? 25-36/37/38
????? 26-45
????(UN No.) 2811
WGK ?? 3
?? ?? 6.1
?? ?? IRRITANT
????
HS ?? 2933998090
????(GHS): GHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H301 ??? ??? ?? ?? ?? - ?? ?? 3 ?? GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
1
2 0

4-???(1H)??? C??? ??, ??, ??

??

4-Bromo-1H-indazole is a derivative indazole which has a heterocyclic structure made up of benzene and pyrazole rings. Indazoles are an important class of heterocyclic compounds with a wide range of application as biologic and pharmaceutic agents. Indazole derivatives have a wide range of biological activities. For instance, indazole derivatives show vasorelaxant and anti-aggregator activities by stimulating NO release and increasing cGMP levels. Recent medical research and development studies resulted in the production of indazole derivatives for the treatment of osteoporosis, inflammatory diseases and neurodegenerative disorders. 4-bromo-1H indazole molecule is a much stronger inhibitor of 6-bromo-1H indazole and 7-bromo-1H indazole. 4-Bromo-1H-indazole may be strong inhibitor candidate for LPO and that caution should be exercised when using medicines containing indazole derivatives[1].

??? ??

brown powder

4-???(1H)??? ?? ?? ? ???

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4-???(1H)??? ?? ??

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4-???(1H)??? ?? ??:

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