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72263-05-9
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CONGLOBATIN
???(??):
NGLOBATIN;FW-04-806;CONGLOBATIN;Conglobactin;Conglobatin, >=99%;Conglobatin (FW-04-806);(3E,5R,7S,8S,11E,13R,15S,16S)-3,5,7,11,13,15-Hexamethyl-8,16-bis(5-oxazolylmethyl)-1,9-dioxacyclohexadeca-3,11-diene-2,10-dione;1,9-Dioxacyclohexadeca-3,11-diene-2,10-dione, 3,5,7,11,13,15-hexamethyl-8,16-bis(5-oxazolylmethyl)-, (3E,5R,7S,8S,11E,13R,15S,16S)-;(3E,5R,7S,8S,11E,13R,15S,16S)-3,5,7,11,13,15-hexamethyl-8,16-bis[(1,3-oxazol-5-yl)methyl]-1,9-dioxacyclohexadeca-3,11-diene-2,10-dione
CBNumber:
CB3460272
???:
C28H38N2O6
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498.61
MOL ??:
72263-05-9.mol
MSDS ??:
SDS

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1.060±0.06 g/cm3 (20 ºC 760 Torr)
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-20°C
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DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
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White to off-white

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WGK ?? 3
HS ?? 29419000

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Isolated from Streptomyces conglobatus, conglobatin has a unusual, dimeric, macrolide dilactone structure with pendant oxazole groups. Conglobatin exhibits an IC50 of 0.63 μg/ml in a NFAT-dependant transcription assay. No toxicity was observed at doses up to 1000 mg/kg when administered to mice either orally or interperitoneally.

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