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?? ??:: 75504-34-6

???:: ????-N-????

???(??):: ????-N-????

???:: TAMOXIFEN-N-OXIDE

???(??):: Tamoxifen epoxide;TAMOXIFEN-N-OXIDE;Tamoxifen Citrate Impurity 12 (Tamoxifen N-oxide);(Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine-N-oxide;2-[4-[(1Z)-1,2-Diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethylethanamine N-oxide;Ethanamine, 2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, N-oxide, (Z)-;Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-, N-oxide

CBNumber:: CB2506809

???:: C26H29NO2

??? ??:: 387.51

MOL ??:: 75504-34-6.mol

?? ?? 35

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?? ??: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

???: DMF: 20 mg/mL; DMSO: 2 mg/mL; Ethanol: 20 mg/mL; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/mL

??? ??: ??? ??

?? ?? (pKa): 4.49±0.40(Predicted)

??: White to off-white

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Danger

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H360	?? ?? ????? ??? ??? ? ??	???? ??	?? 1A, 1B	??

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P201	?? ? ?? ???? ?????.
P202	?? ?? ?? ??? ?? ???? ??? ???? ???.
P280	????/???/???/?????? ?????.
P308+P313	?? ?? ??? ???? ???? ??· ??? ????.
P405	???? ?????.
P501	...? ??? / ??? ?? ???.

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A metabolite of Tamoxifen, a nonsteroidal estrogen antagonist of interest in the treatment of some forms of breast cancer. Tamoxifen is a Protein Kinase C inhibitor, and induces apoptosis in human malignant glioma cell lines

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ChEBI: An N-oxide derived from tamoxifen.

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????-N-???? ?? ??:

?????????? desdimethyltamoxifen Tamoxifen Impurity 3 4-Benzyloxy β-Hydroxy TaMoxifen TaMoxifen DiMer 1-(4-(2-Dimethylamino)-2-ethoxyphenyl butanone N-Desmethyl-4-hydroxy Tamoxifen β-D-Glucuronide (E/Z Mixture) 4Hydroxy Tamoxifen Tamoxifen EP Impurity D (E)-4-Alloxycarboxyl Tamoxifen Endoxifen Droloxifene (E)-4-Acetoxy Tamoxifen N-Desmethyl Tamoxifen Methanethiosulfonate 2-[4-[(E)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethyl-ethanamine alpha-[4-[2-(dimethylamino)ethoxy]phenyl]-beta-ethyl-alpha-phenylphenethyl alcohol (E)-4-Hydroxy-N-desmethyl Tamoxifen 4-HYDROXYTAMOXIFEN

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