Poziotinib (HM781-36B)
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Poziotinib (HM781-36B) ??
- ???
- 187 - 190° C
- ?? ?
- 629.7±55.0 °C(Predicted)
- ??
- 1.409±0.06 g/cm3(Predicted)
- ?? ??
- -20°C Freezer, Under inert atmosphere
- ???
- ?????(?? ???), DMSO(?? ???, ?????)
- ?? ?? (pKa)
- 5.35±0.30(Predicted)
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- CAS ??????
- 1092364-38-9
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Poziotinib (HM781-36B) C??? ??, ??, ??
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Poziotinib is a TKI that covalently and irreversibly inhibits EGFR and HER2, and is unique because of its small terminal group and flexible quinazoline core. Its small size and flexibility allow it to evade the steric hindrance which affects other EGFR TKIs [138].??
Poziotinib can be used to inhibit the growth of cancer cells.Poziotinib (HM781-36B) ?? ?? ? ???
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6-Quinazolinol, 4-[(3,4-dichloro-2-fluorophenyl)amino]-7-methoxy-, 6-acetate
3,4-????-7-???-4-??????-6-??????
1-[4-[[(4-Methylphenyl)sulfonyl]oxy]-1-piperidinyl]-2-propen-1-one
4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-ol
3,4-????-2-???????
?????????
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Poziotinib (HM781-36B) ?? ??
???( 197)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| HangZhou RunYan Pharma Technology Co.,LTD. | +8618882027439 |
sales2@runyanpharma.com | China | 302 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 |
info@dakenam.com | China | 19852 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 33025 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
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| TianYuan Pharmaceutical CO.,LTD | +86-755-23284190 13684996853 |
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| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
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| Shenzhen Excellent Biotech Co., Ltd. | 13480692018 |
ramyan@ex-biotech.com | CHINA | 954 | 58 |
| Jurong Coupling Biotechnology Co., Ltd. | 13656108824 |
coupling278191416@hotmail.com | CHINA | 184 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32159 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 |
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