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Mirtazapine

Mirtazapine ??? ???
?? ??:
85650-52-8
???:
Mirtazapine
???(??):
Mirtazapine Anhydrous;REMERON;MIRTAZEPINE;ZISPIN;ORG-3770;Mirtazapin;MIRTAZAPINE;MIRTAZANINE;Mirtazapine-d7;Mirtazapine>
CBNumber:
CB0463388
???:
C17H19N3
??? ??:
265.35
MOL ??:
85650-52-8.mol
MSDS ??:
SDS

Mirtazapine ??

???
114-116°C
?? ?
432.4±45.0 °C(Predicted)
??
1.22±0.1 g/cm3(Predicted)
???
9°C
?? ??
2-8°C
???
DMSO: ~8mg/mL, ???
??? ??
??
??? ??
??? ??
?? ?? (pKa)
8.10±0.20(Predicted)
??
???
BCS Class
1
CAS ??????
85650-52-8(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn
?? ???? ?? 22
????? 22-24/25
????(UN No.) UN1230 - class 3 - PG 2 - Methanol, solution
WGK ?? 3
RTECS ?? UQ4410250
HS ?? 29339900
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H336 ?? ?? ???? ??? ? ?? ?????? ?? ??(1? ??);???? ?? 3 ?? P261, P271, P304+P340, P312,P403+P233, P405, P501
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P271 ?? ?? ??? ? ?? ???? ?????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
NFPA 704
3
0 0

Mirtazapine C??? ??, ??, ??

??? ??

White Solid

??

Mirtazapine (Remeron, Avanza) is a potent tetracyclic antidepressant. Mirtazapine (Remeron, Avanza) used primarily in the treatment of depression. It is also sometimes used as a hypnotic, antiemetic, and appetite stimulant, and for the treatment of anxiet

?? ??

Mirtazapine is a tetracyclic antidepressant marketed under the trade names Remeron?, Avanza, or Zispin for treatment of depression.?This Certified Spiking Solution? is suitable for LC/MS or GC/MS applications in forensic analysis, clinical toxicology, or urine drug testing.

???? ??

Antidepressant agent; potent 5-HT 2 , 5-HT 3 and histamine H 1 receptor antagonist and moderately potent α 2 -adrenoceptor antagonist (pK i values are 8.05, ~ 8.1, 9.3 and 6.95 respectively). Enhances noradrenalin (NA) release in rat brain via inhibition of α 2 -adrenergic autoreceptors and displays only weak affinity for monoamine transporters (pK i values are 5.6, < 5 and < 5.1 for inhibition of NA, dopamine and 5-HT uptake respectively). Increases hippocampal NA and 5-HT levels in rats following systemic administration in vivo .

Mirtazapine ?? ?? ? ???

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Mirtazapine ?? ??

???( 324)?? ??
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Mirtazapine ?? ??:

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