ケトロラク
安全性情報(bào)
- リスクと安全性に関する聲明
- 危険有害性情報(bào)のコード(GHS)
| RIDADR |
3249 |
|
|
| 國連危険物分類 |
6.1(a) |
|
|
| 容器等級 |
II |
|
|
| HSコード |
2933998090 |
|
|
| 毒性 |
LD50 orally in mice: ~200 mg/kg (Rooks) |
|
|
| 絵表示（GHS） |
|
| 注意喚起語 |
警告 |
| 危険有害性情報(bào) |
| コード |
危険有害性情報(bào) |
危険有害性クラス |
區(qū)分 |
注意喚起語 |
シンボル |
P コード |
| H302 |
飲み込むと有害 |
急性毒性、経口 |
4 |
警告 |
|
P264, P270, P301+P312, P330, P501 |
| H315 |
皮膚刺激 |
皮膚腐食性/刺激性 |
2 |
警告 |
|
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
強(qiáng)い眼刺激 |
眼に対する重篤な損傷性/眼刺激 性 |
2A |
警告 |
|
P264, P280, P305+P351+P338,P337+P313P |
| H332 |
吸入すると有害 |
急性毒性、吸入 |
4 |
警告 |
|
P261, P271, P304+P340, P312 |
| H335 |
呼吸器への刺激のおそれ |
特定標(biāo)的臓器毒性、単回暴露； 気道刺激性 |
3 |
警告 |
|
|
|
| 注意書き |
| P261 |
粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。 |
| P280 |
保護(hù)手袋/保護(hù)衣/保護(hù)眼鏡/保護(hù)面を著用するこ と。 |
| P305+P351+P338 |
眼に入った場合：水で數(shù)分間注意深く洗うこと。次にコ ンタクトレンズを著用していて容易に外せる場合は外す こと。その後も洗浄を続けること。 |
|
| メーカー |
製品番號 |
製品説明 |
CAS番號 |
包裝 |
価格 |
更新時(shí)間 |
購入 |
|
富士フイルム和光純薬株式會(huì)社(wako)
|
W01FLC242512 |
5-ベンゾイル-2,3-ジヒドロ-1H-ピロリジン-1-カルボン酸
5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid |
74103-06-3 |
250mg |
￥39600 |
2018-12-26 |
購入 |
ケトロラク 化學(xué)特性,用途語,生産方法
効能
鎮(zhèn)痛薬, 抗炎癥薬, シクロオキシゲナーゼ阻害薬
化學(xué)的特性
Light yellow solid
使用
antiarrhythmic
適応癥
Ketorolac (Toradol), an NSAID chemically related
to indomethacin and tolmetin, is mainly used as an analgesic,
not for the treatment of inflammatory disease. It
is available in oral, parenteral, and topical formulations.
世界保健機(jī)関（WHO）
Ketorolac is a nonsteroidal anti-inflammatory agent used in the
management of moderate to severe acute post-operative pain. It remains on the
market in many countries with restrictions on its use.
生物學(xué)の機(jī)能
Ketorolac (Toradol) is an NSAID with very mild antiinflammatory
and antipyretic activity. It is a potent analgesic
for postoperative pain. Its efficacy is equivalent to
that of low doses of morphine in the control of pain. For
this reason it is often combined with opioids to reduce
opioid dose and related side effects while providing adequate
pain relief. It is also used to replace the opioids in
some patients with opioid sensitivity. The mechanism of
action of ketorolac involves the inhibition of COX and
decreased formation of prostaglandins. However, some
evidence exists that ketorolac may stimulate the release
of endogenous opioids as a part of its analgesic activity.
一般的な説明
Ketorolac tromethamine (Toradol), marketed as a mixture of(R)- and (S)-ketorolac enantiomers, is a potent NSAID analgesicindicated for the treatment of moderately severe, acutepain. It should be noted that the pharmacokinetic dispositionof ketorolac in humans is subject to marked enantioselectivity.Thus, it is important to monitor the individual blood levelsso an accurate assessment of its therapeutic action can bemade correctly. However, it should be noted that, beingone of the conventional NSAIDs with highest risk of GIcomplications, its administration should not exceed 5 days.
ケトロラク 上流と下流の製品情報(bào)
原材料
準(zhǔn)備製品
ケトロラク 生産企業(yè)
Global( 276)Suppliers
74103-06-3(ケトロラク)キーワード:
- 74103-06-3
- Ketorolac Solution, 100ppm
- Ketorolac, >=98%
- 3-dihydro-5-benzoyl-(+-)-1h-pyrrolizine-1-carboxylicaci
- rs37619
- KETOROLAC
- KETOROLAC-D5
- KETOROLAC TROMETHAMINE, USP STANDARD
- 5-(phenylcarbonyl)-2,3-dihydro-1H-pyrrolizine-1-ca
- Ketoralac
- 3-dihydro-5-benzoyl- (+-)-1h-pyrrolizine-1-carboxylic acid
- Dolac
- Lixidol
- Tm-asyn
- Toratex
- (1S)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
- (1S)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1β-carboxylic acid
- 5-phenylcarbonyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
- Ketorolac-13C6
- (1RS)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
- [1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]ammonium
- 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate
- Ketorolac trometamol for peak identification CRS
- Ketorolac trometamol CRS
- 5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic?acid. OR (Ketorolac Base)
- Ketorolac USP/EP/BP
- Ketorolac (RS37619)
- KetorolacQ: What is
Ketorolac Q: What is the CAS Number of
Ketorolac Q: What is the storage condition of
Ketorolac Q: What are the applications of
Ketorolac
- Ketorolac 13C6Q: What is
Ketorolac 13C6 Q: What is the CAS Number of
Ketorolac 13C6 Q: What is the storage condition of
Ketorolac 13C6 Q: What are the applications of
Ketorolac 13C6
- Fluoxetin
- Acular
- ケトロラク
- (S)-ケトロラック
- (1S)-5-ベンゾイル-2,3-ジヒドロ-1H-ピロリザイン-1-カルボン酸
- (S)-(-)-ケトロラック
- ケトロラク酸
- (1S)-5-ベンゾイル-2,3-ジヒドロ-1H-ピロリザイン-1β-カルボン酸
- rac-(1R*)-5-ベンゾイル-2,3-ジヒドロ-1H-ピロリザイン-1-カルボン酸
- ケトロラック
- (-)-ケトロラック
- 5-ベンゾイル-2,3-ジヒドロ-1H-ピロリジン-1-カルボン酸
- 非ステロイド系消炎薬
- 酵素阻害剤
- 抗リウマチ薬