Pilsicainide hydrochloride
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- CAS-Nr.
- 88069-49-2
- Englisch Name:
- Pilsicainide hydrochloride
- Synonyma:
- Pilsinic;Rizumcote;Alisrythm;Tatsupilljin;PILSICAININIDE;Pilsicainide hydrochoride;Pilsicainide-Hydrochlordie;Pilzicainide hydrochloride;PILSICAINIDE HYDROCHLORIDE;Pilsicainide HCl, 10 mM in DMSO
- CBNumber:
- CB9699294
- Summenformel:
- C17H24N2O
- Molgewicht:
- 272.39
- MOL-Datei:
- 88069-49-2.mol
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Pilsicainide hydrochloride Eigenschaften
- Schmelzpunkt:
- 212-214°
- storage temp.
- room temp
- L?slichkeit
- Chloroform (Slightly), Water (Slightly)
- Aggregatzustand
- powder
- Farbe
- white to beige
- Wasserl?slichkeit
- deionized water: >5mg/mL
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| RIDADR |
UN 2811 6.1 / PGIII |
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| WGK Germany |
3 |
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| HS Code |
2933.99.7000 |
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| Toxizit?t |
LD50 in mice (mg/kg): 410 s.c. (Miyano, 1985) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
![GHS hazard pictograms]() src="/GHS06.jpg" width="20" height="20" /> |
P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P405 |
Unter Verschluss aufbewahren. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Pilsicainide hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Pilsicainide hydrochloride is a new pynolizidine lidocaine derivative with
antiarrhythmic activity. It is the first pharmaceutical product introduced by Suntory
and was solely developed in Japan. The compound is reported to be highly effective in
the treatment of premature ventricular contraction. It has no anticholinergic or CNS
activity and is not as likely as other class 1C antiarrhythmics to have restricted
indications.
Verwenden
Pilsicainide hydrochloride has been used as a sodium channel blocker:
- to study its effects on electrophysiological parameters in guinea pig pulmonary vein preparation
- to study its effects on Ca2+?release and arrhythmic events in Andersen-Tawil syndrome induced pluripotent stem cells (ATS-iPSC)-derived cardiomyocytes
- to study its electrophysiological effects on the guinea pig atrium
Pilsicainide hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Pilsicainide hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 112)Lieferanten
88069-49-2()Verwandte Suche:
- Pilzicainide hydrochloride
- Rizumcote
- Tatsupilljin
- Pilsicainide-Hydrochlordie
- N-(2,6-Dimethylphenyl)-2-(hexahydro-1H-pyrrolizin-7a-yl)acetamide hydrochloride
- n-(2,6-dimethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide hydrochloride
- PILSICAINIDE HYDROCHLORIDE
- PILSICAINIDE HYDROCHLORIDE HEMIHYDRATE
- PILSICAININIDE
- Pilsicainide hydrochoride
- PILSICAINIDEHYDROCHLORIDE(FORRESEARCHONLY)
- Pilsicainide Hydrochloride and intermediates
- Alisrythm
- Pilsinic
- Pilsicainide hydrochloride USP/EP/BP
- C17H24N2O Pilsicainide hydrochloride 88069-49-2
- atrial tachyarrhythmias,SUN-1165,Pilsicainide HCl,antiarrhythmic,inhibit,orally active,SUN1165,Inhibitor,Na+ channels,Na channels,Pilsicainide,Sodium Channel
- Pilsicainide HCl, 10 mM in DMSO
- 88069-49-2
- C17H24N2O
- C17H24N2OHCl
- C17H24N2OHCl12H2O
- APIs
