Protopin
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- CAS-Nr.
- 130-86-9
- Bezeichnung:
- Protopin
- Englisch Name:
- Protopine
- Synonyma:
- BIFLORIN;Protopin;PROTOPINE;Biflorine;Corydinine;Tangeratin;Hypercorine;AKOS 243-72;Corydalis C;Protopine-RM
- CBNumber:
- CB9347526
- Summenformel:
- C20H19NO5
- Molgewicht:
- 353.37
- MOL-Datei:
- 130-86-9.mol
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Protopin Eigenschaften
- Schmelzpunkt:
- 203-205?C
- Siedepunkt:
- 486.8°C (rough estimate)
- Dichte
- 1.399 (calc)
- Brechungsindex
- 1.5800 (estimate)
- storage temp.
- Inert atmosphere,2-8°C
- Wasserl?slichkeit
- Insoluble in water
- L?slichkeit
- DMSO : 12.5 mg/mL (35.37 mM; Need ultrasonic)
- pka
- 7.86±0.20(Predicted)
- Aggregatzustand
- powder to crystal
- Farbe
- White to Light gray to Light yellow
- LogP
- 3.760 (est)
- NIST chemische Informationen
- Protopine(130-86-9)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
24/25 |
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| RIDADR |
1544 |
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| RTECS-Nr. |
VS2800000 |
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| HazardClass |
6.1(b) |
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| PackingGroup |
III |
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| HS Code |
29391900 |
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| Giftige Stoffe Daten |
130-86-9(Hazardous Substances Data) |
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| Toxizit?t |
guinea pig,LD50,intraperitoneal,116mg/kg (116mg/kg),Therapie. Vol. 28, Pg. 767, 1973. |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Protopin Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Off-White Solid
Verwenden
Protopine is a Ca2+ channel blocker and antiplatelet agent. Immunomodulator
Definition
ChEBI: A dibenzazecine alkaloid isolated from Fumaria vaillantii.
Allgemeine Beschreibung
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
l?uterung methode
It crystallises from EtOH/CHCl3. The picrate has m ~240o(dec). [Beilstein 27 H 558, 17 I 568, 17 II 620, 17 III/IV 6881.]
Protopin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Protopin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 203)Lieferanten
130-86-9(Protopin)Verwandte Suche:
Methylacetat
Pirimiphos-methyl (ISO)
Kresoxim-methyl
Tribenuron methyl
2-[[[[(4-Methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl]amino]sulfonyl]benzoic acid methyl ester
Methylsalicylat
Thiophanat-methyl
3,3'-(3,7,12,17-Tetramethyl-8,13-divinylporphin-2,18-diyl)di(propionsure)
Methyl
Brommethan
3'-Methoxypropiophenon
1-(1,3-Benzodioxol-5-yl)aceton
Protopinhydrochlorid
4,4'-Dimethoxydesoxybenzoin
1-(3-Methoxyphenyl)aceton
Parathion-methyl (ISO)
Opium
Benzyl-4-hydroxyphenylketon
- 7,13a-Secoberbin-13a-one, 7-methyl-2,3:9,10-bis(methylenedioxy)-
- 7-Methyl-6,8,9,16-tetrahydrodi[1,3]benzodioxolo[4,5-c:5,6-g]azecin-15(7H)-one
- Biflorine
- Bis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-
- Corydinine
- Hypercorine
- Protopin
- BIFLORIN
- AKOS 243-72
- 5,7-DIHYDROXY-2-METHYLCHROMONE-6-C-BETA-D-GLUCOPYRANOSIDE
- PROTOPINE
- 4,6,7,14-Tetrahydro-5-methyl-bis[1,3]benzodioxolo[4,5-c-5',6'-g] azecin-13(5H)-one
- 7-Methyl-2,3:9,10-bis(methylenedioxy)-7,13a-secoberbin-13a-one
- 5-Methyl-9,10-(methylenedioxy)-4,6,7,13-tetrahydrobenzo[e]-1,3-dioxolo[4,5-l][2]benzazecine-12(5H)-one
- 6-Methyl-3,4-(methylenebisoxy)-10,11-(methylenebisoxy)-5,6,7,8-tetrahydrodibenzo[c,g]azecine-13(14H)-one
- 7-Methyl-6,7,8,9-tetrahydro-[1,3]dioxolo[4',5':5,6]benzo[1,2-c][1,3]dioxolo[5',4':4,5]benzo[1,2-g]azecin-15(16H)-one
- 4,6,7,14-Tetrahydro-5-Methyl-
- Tangeratin
- Corydalis C
- Protopine (Corydinine)
- Protopine, 98%, from Corydalis yanhusuo W. T. Wang ex Z. Y. Su et C. Y. Wu
- Protopine USP/EP/BP
- 1H-Isoindole-1,3(2H)-dione,2-(3-butyn-2-yl)-
- Protopine 100 μg/ml Acetonitrile
- Protopine-RM
- Protopine, 10 mM in DMSO
- 130-86-9
- C20H19O5
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
