Elamipretide
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Elamipretide Eigenschaften
- Dichte
- 1.34±0.1 g/cm3(Predicted)
- L?slichkeit
- Methanol (Slightly), Water (Slightly)
- pka
- 10.10±0.25(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Sequenz
- H-d-Arg-dimethylTyr-Lys-Phe-NH2
- Stabilit?t:
- Hygroscopic
- InChIKey
- SFVLTCAESLKEHH-WKAQUBQDSA-N
- SMILES
- C(N)(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC1=C(C)C=C(O)C=C1C)NC(=O)[C@@H](CCCNC(N)=N)N
Sicherheit
Elamipretide Chemische Eigenschaften,Einsatz,Produktion Methoden
Mechanism of action
Elamipretide can inhibit the production of pathogenic ROS (reactive oxygen species) and restore mitochondrial ATP synthesis. Currently, the most accepted mechanism for these two actions is the direct interaction between Elamipretide and cardiolipin.Clinical Use
Barth syndrome is an ultra-rare genetic condition characterized by cardiac abnormalities leading to exercise intolerance, muscle weakness, debilitating fatigue, heart failure, recurrent infections, and delayed growth. There are currently no FDA- or EMA-approved therapies for patients with Barth syndrome. Elamipretide has an Orphan Drug, Fast Track and Rare Pediatric Designation from the FDA and Orphan Drug Designation from the EMA for treating Barth syndrome.Nebenwirkungen
Side effects of elamipretide include:Mild redness or itching at the injection site
Headache
Dizziness
Elamipretide Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Elamipretide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 144)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Apeloa production Co.,Limited | +8619933239880 |
admin@apcl.com.cn | China | 861 | 58 |
Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 |
sarah@tnjone.com | China | 1143 | 58 |
Qingdao Xinli Technology Development Co., Ltd. | +8616632313095 |
xinlikeji01@qdxlchem.com | China | 124 | 58 |
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +8615350851019 |
admin@86-ss.com | China | 1001 | 58 |
Shandong Huizhihan Supply Chain Co., Ltd | +8613363081709 |
3957328362@qq.com | China | 300 | 58 |
American HealthyMorph LLC | +8613363867578 |
nancyyuan133@163.com | China | 168 | 58 |
Dorne Chemical Technology co. LTD | +86-86-13583358881 +8618560316533 |
Ethan@dornechem.com | China | 3091 | 58 |
Hebei Yime New Material Technology Co., Ltd. | +86-66697723 +86-17703311139 |
admin@china-yime.com | China | 563 | 58 |
Shanghai Yunao International Trade Co., Ltd | +8617621705551 |
asdf@shanghaihg.cn | China | 264 | 58 |
qingdao future trading Co., Ltd | +86-13335044410 +86-13335044410 |
cui56813@163.com | China | 110 | 58 |
736992-21-5()Verwandte Suche:
- D-Arginyl-2,6-diMethyl-L-tyrosyl-L-lysyl-L-phenylalaninaMide
- L-Phenylalaninamide, D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-
- Elamipretide
- Elamipretide (TFA salt)
- SS-31;MTP-131;BENDAVIA
- Bendavia)
- Elamipretide (SS-31
- ELAMIPRETIDE, >99%
- Elamipretide,MTP-131,RX-31,SS-31, >99%
- Elamipretide (MTP-131
- ELAMIPRETIDE (MTP-131;RX-31;SS-31)
- RX-31
- SS-31)
- Elamipretide (SS-31) acetate
- (S)-6-Amino-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-((R)-2-amino-5-guanidinopentanamido)-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)hexanamide
- Elamipretide(HY-P0125
- Centanafadine
- MTP-131
- SS-31, Elamipretide
- Elamipretide acetate
- Elamipretide、SS-31、H2N-D-Arg-Dmt-Lys-Phe-NH2
- SS-31 10mg/20mg
- 736992-21-5
- 736992-21-5