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Elamipretide

Elamipretide Struktur
736992-21-5
CAS-Nr.
736992-21-5
Englisch Name:
Elamipretide
Synonyma:
MTP-131;Centanafadine;SS-31, Elamipretide;Elamipretide acetate;RX-31;SS-31);Bendavia);Elamipretide;ELAMIPRETIDE, >99%;Elamipretide (SS-31
CBNumber:
CB92708860
Summenformel:
C32H49N9O5
Molgewicht:
639.79
MOL-Datei:
736992-21-5.mol

Elamipretide Eigenschaften

Dichte
1.34±0.1 g/cm3(Predicted)
L?slichkeit
Methanol (Slightly), Water (Slightly)
pka
10.10±0.25(Predicted)
Aggregatzustand
Solid
Farbe
White to Off-White
Sequenz
H-d-Arg-dimethylTyr-Lys-Phe-NH2
Stabilit?t:
Hygroscopic
InChIKey
SFVLTCAESLKEHH-WKAQUBQDSA-N
SMILES
C(N)(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC1=C(C)C=C(O)C=C1C)NC(=O)[C@@H](CCCNC(N)=N)N

Sicherheit

Elamipretide Chemische Eigenschaften,Einsatz,Produktion Methoden

Mechanism of action

Elamipretide can inhibit the production of pathogenic ROS (reactive oxygen species) and restore mitochondrial ATP synthesis. Currently, the most accepted mechanism for these two actions is the direct interaction between Elamipretide and cardiolipin.

Clinical Use

Barth syndrome is an ultra-rare genetic condition characterized by cardiac abnormalities leading to exercise intolerance, muscle weakness, debilitating fatigue, heart failure, recurrent infections, and delayed growth. There are currently no FDA- or EMA-approved therapies for patients with Barth syndrome. Elamipretide has an Orphan Drug, Fast Track and Rare Pediatric Designation from the FDA and Orphan Drug Designation from the EMA for treating Barth syndrome.

Nebenwirkungen

Side effects of elamipretide include:
Mild redness or itching at the injection site
Headache
Dizziness

Elamipretide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Elamipretide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 134)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Apeloa production Co.,Limited
+8619933239880
admin@apcl.com.cn China 861 58
Shandong Huisheng Import & Export Co., Ltd.
+86-13176845580 +86-13176845580
da@zhongda-biotech.com China 232 58
Zhejiang Hangyu API Co., Ltd
+8617531972939
anna@api-made.com China 2943 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649
sarah@tnjone.com China 1143 58
Qingdao Xinli Technology Development Co., Ltd.
+8616632313095
xinlikeji01@qdxlchem.com China 124 58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
+8615350851019
admin@86-ss.com China 1001 58
Shandong Huizhihan Supply Chain Co., Ltd
+8613363081709
3957328362@qq.com China 300 58
American HealthyMorph LLC
+8613363867578
13363867578@163.com China 150 58
Dorne Chemical Technology co. LTD
+86-86-13583358881 +8618560316533
Ethan@dornechem.com China 3097 58
Hebei Yime New Material Technology Co., Ltd.
+86-66697723 +86-17703311139
admin@china-yime.com China 563 58

736992-21-5()Verwandte Suche:


  • D-Arginyl-2,6-diMethyl-L-tyrosyl-L-lysyl-L-phenylalaninaMide
  • L-Phenylalaninamide, D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-
  • Elamipretide
  • Elamipretide (TFA salt)
  • SS-31;MTP-131;BENDAVIA
  • Bendavia)
  • Elamipretide (SS-31
  • ELAMIPRETIDE, >99%
  • Elamipretide,MTP-131,RX-31,SS-31, >99%
  • Elamipretide (MTP-131
  • ELAMIPRETIDE (MTP-131;RX-31;SS-31)
  • RX-31
  • SS-31)
  • Elamipretide (SS-31) acetate
  • (S)-6-Amino-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-((R)-2-amino-5-guanidinopentanamido)-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)hexanamide
  • Elamipretide(HY-P0125
  • Centanafadine
  • MTP-131
  • SS-31, Elamipretide
  • Elamipretide acetate
  • Elamipretide、SS-31、H2N-D-Arg-Dmt-Lys-Phe-NH2
  • 736992-21-5
  • 736992-21-5
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