Diazoessigs?ure-ethylester
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- CAS-Nr.
- 623-73-4
- Bezeichnung:
- Diazoessigs?ure-ethylester
- Englisch Name:
- Ethyl diazoacetate
- Synonyma:
- Ethyl 2-diazoacetate;Daae;Diazoacetic ester;Ethyl diazoate;diazoaceticester;diazoacetate soL;ETHYL DIAZOACETATE;Ethyl diazoethanoate;Ethylene Diazo Acetate;Diazoacetic acid ethyl
- CBNumber:
- CB9241343
- Summenformel:
- C4H6N2O2
- Molgewicht:
- 114.1
- MOL-Datei:
- 623-73-4.mol
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Diazoessigs?ure-ethylester Eigenschaften
- Schmelzpunkt:
- -22 °C (lit.)
- Siedepunkt:
- 140-141 °C/720 mmHg (lit.)
- Dichte
- 1.085 g/mL at 25 °C (lit.)
- Brechungsindex
- n20/D 1.46(lit.)
- Flammpunkt:
- 115 °F
- storage temp.
- 2-8°C
- L?slichkeit
- Chloroform (Slightly), DMSO (Soluble), Hexane (Slightly), Methanol (Slightly)
- Aggregatzustand
- Oil
- Farbe
- Light Yellow to Orange
- Merck
- 13,3021
- BRN
- 107654
- NIST chemische Informationen
- Ethyl diazoacetate(623-73-4)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
  
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H226 |
Flüssigkeit und Dampf entzündbar. |
Entzündbare Flüssigkeiten |
Kategorie 3 |
Warnung |
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| H242 |
Erw?rmung kann Brand verursachen. |
Organische Peroxide |
Typen C & D |
Achtung
Warnung |
![GHS hazard pictograms]() src="/GHS02.jpg" width="20" height="20" /> |
P210, P220, P234, P280, P370+P378,P403+P235, P411, P420, P501 |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H351 |
Kann vermutlich Krebs verursachen. |
Karzinogenit?t |
Kategorie 2 |
Warnung |
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P201, P202, P281, P308+P313, P405,P501 |
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| Sicherheit |
| P210 |
Von Hitze, hei?en Oberfl?chen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P303+P361+P353 |
BEI BERüHRUNG MIT DER HAUT (oder dem Haar): Alle kontaminierten Kleidungsstücke sofort ausziehen. Haut mit Wasser abwaschen oder duschen. |
| P308+P313 |
BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P370+P378 |
Bei Brand: zum L?schen verwenden. |
| P403+P235 |
An einem gut belüfteten Ort aufbewahren. Kühl halten. |
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Diazoessigs?ure-ethylester Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R5:Beim Erw?rmen explosionsf?hig.
R10:Entzündlich.
R22:Gesundheitssch?dlich beim Verschlucken.
R40:Verdacht auf krebserzeugende Wirkung.
S-S?tze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Chemische Eigenschaften
Liquid.
Verwenden
Reagent for ruthenium-catalyzed asymmetric cyclopropanation of alkenes.1
Hazard
Flammable liquid that explodes when
heated.
Sicherheitsprofil
Poison by ingestion and
intravenous routes. Questionable carcinogen
with experimental carcinogenic and
tumorigenic data. Can explode. Explodes on
contact with tris(dimethy1amino) antimony.
When heated to decomposition it emits
toxic fumes of NOx. See also ESTERS.
l?uterung methode
It is a very volatile yellow oil with a strong pungent odour. EXPLOSIVE [distillation even under reduced pressure is dangerous and may result in an explosion — TAKE ALL THE NECESSARY PRECAUTIONS IF DISTILLATION IS TO BE CARRIED OUT]. It explodes in contact with conc H2SO4-trace acid causes rapid decomposition. It is slightly soluble in H2O, but is miscible with EtOH, *C6H6, pet ether and Et2O. To purify, dissolve it in Et2O [using CH2Cl2 instead of Et2O, protects the ester from acid], wash it with 10% aqueous Na2CO3, dry (MgSO4), filter and repeat as many times as possible until the Et2O layer loses its yellow colour, then remove the solvent below 20o (vacuum). Note that prolonged heating may lead to rapid decomposition and low yields. It can also be purified by steam distillation under reduced pressure but with considerable loss in yield. Place the residual oil in a brown bottle, keep below 10o, and use as soon as possible without distilling. For preparing esters usually the ethereal solution is used directly without purification. [Womack & Nelson Org Synth Coll Vol III 392 1955, UV: Miller & White J Am Chem Soc 79 5974 1957, Fieser 1 367 1967, Beilstein 3 IV 1495.]
Diazoessigs?ure-ethylester Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2,2-Dimethyl-3-(2-methylpropyl)cyclopropanecarboxylic acid p-(methoxymethyl)benzyl ester
Ethyl-2,2-dimethyl-3-(2-methylpropenyl)cyclopropancarboxylat
Ethylglycinat
Ethylglykolat
Benzeneacetic acid, α-(hydroxymethylene)-, ethyl ester, (αZ)-
Heptanoic acid, 2-methyl-3-oxo-, ethyl ester
2-Pentenedioic acid, diethyl ester, (Z)- (9CI)
2-Oxiranecarboxylicacid, 3-(trichloromethyl)-, ethyl ester
ETHYL 3-BUTYNOATE
Ethyl-3-methoxyphenylacetat
Ethyl 4-methoxycinnamate
2-HYDROXYMETHYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER
Diethyl iminodiacetate
ethyl 5-(hydroxymethyl)-1H-pyrazole-3-carboxylate
Diazoessigs?ure-ethylester Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 172)Lieferanten
623-73-4(Diazoessigs?ure-ethylester)Verwandte Suche:
- Acetic acid, diazo-, ethyl ester
- Diazoacetic acid ethyl ester
- diazoaceticacid,ethylester
- diazo-aceticaciethylester
- diazoaceticester
- Diazoessigsaeure-aethylester
- Ethoxycarbonyldiazomethane
- Ethyl diazoethanoate
- ETHYL DIAZOACETATE
- Ethylene Diazo Acetate
- ETHYL DIAZOACETATE ETHYL DIAZOETHANOATE
- 2-Diazoacetic acid ethyl
- Diazoacetic acid ethyl
- Ethyl diazoate
- Acetic acid, 2-diazo-,ethyl ester
- Ethyl diazoacetate contains >=13 wt. % dichloroMethane
- Ethyl diazoacetate solution, 95%
- 2-Diazoacetic acid ethyl ester solution
- Ethyl diazoacetate solution,90% wt in dichloromethane
- (e)-2-diazonio-1-ethoxyethenolate
- Ethyl 2-diazoacetate (diluted with ~10% dichloromethane, wt/wt)
- Ethyl diazoacetate, 95%, contains 5% CH2Cl2
- diazoacetate soL
- Ethyl Diazoacetate (>
- Ethyl diazoacetate ISO 9001：2015 REACH
- Ethyl Diazoacetate (>90%)
- Ethyldiazoacetate, contains 15 wt. % dichloromethane
- Ethyl diazoacetate 15% solution in DCM
- Daae
- Diazoacetic ester
- Ethyl 2-diazoacetate
- Tenofovir Disoproxil Fumarate Impurity 186
- Ethyl diazoacetate, 80% solution in DCM
- Cilastatin Impurity 10
- 623-73-4
- N2CHCOOC2H5
- NNCHCOOC2H5
- Azo/Diazo Compounds
- Building Blocks
- Nitrogen Compounds
- Organic Building Blocks
- Azo/Diazo Compounds
- Building Blocks
- Chemical Synthesis
- Nitrogen Compounds
- Organic Building Blocks
- Carboxylic
- Azo/Diazo Compounds
- Nitrogen Compounds
- Organic Building Blocks
