4-Hydroxyzimtsure
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- CAS-Nr.
- 7400-08-0
- Bezeichnung:
- 4-Hydroxyzimtsure
- Englisch Name:
- 4-Hydroxycinnamic acid
- Synonyma:
- 4-Hydroxycinnamic acid;4-Hydroxycinnamic acid;P-HYDROXYCINNAMIC ACID;TRANS-4-COUMARIC ACID;TRANS-P-COUMARIC ACID;PHCA;P-CUMARIC ACID;TRANS-P-CUMARIC ACID;4-hydroxylcinnamic acid;3-(4-HYDROXYPHENYL)ACRYLIC ACID
- CBNumber:
- CB9164396
- Summenformel:
- C9H8O3
- Molgewicht:
- 164.16
- MOL-Datei:
- 7400-08-0.mol
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4-Hydroxyzimtsure Eigenschaften
- Schmelzpunkt:
- 214 °C (dec.)(lit.)
- Siedepunkt:
- 251.61°C (rough estimate)
- Dichte
- 1.2132 (rough estimate)
- Brechungsindex
- 1.5380 (estimate)
- storage temp.
- Store below +30°C.
- L?slichkeit
- Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly)
- pka
- 4.65±0.10(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Stabilit?t:
- Light Sensitive
- InChI
- InChI=1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)
- InChIKey
- NGSWKAQJJWESNS-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C=CC1=CC=C(O)C=C1
- LogP
- 1.790
- CAS Datenbank
- 7400-08-0(CAS DataBase Reference)
- NIST chemische Informationen
- 2-Propenoic acid, 3-(4-hydroxyphenyl)-(7400-08-0)
- EPA chemische Informationen
- p-Hydroxycinnamic acid (7400-08-0)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P271 |
Nur im Freien oder in gut belüfteten R?umen verwenden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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4-Hydroxyzimtsure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S22:Staub nicht einatmen.
Chemische Eigenschaften
Light yellow to beige crystalline powder with aroma, soluble in methanol, ethanol, DMSO and other organic solvents, derived from synthesis.
Verwenden
4-Hydroxycinnamic acid is the hydroxy derivative of Cinnamic Acid with antioxidant properties. It is a is a major component of lignocellulose. Studies suggest that 4-Hydroxycinnamic acid may reduce the risk of cancer by reducing the formation of carcinogenic nitrosamines. A recent study reports that 4-Hydroxycinnamic acid may act as a chemical castrator in bees by altering the epression of genes required for ovary development. This compound is common in pollen a major constituent of the worker bee diet, but it is not found in queen bees'royal jelly.
Application
p-Hydroxycinnamic acid is mainly used as an intermediate in the pharmaceutical and perfume industries. It can react with dimethyl sulfate to produce p-anisaldehyde, react with acetaldehyde to produce p-hydroxycinnamaldehyde, and further oxidize it to produce cinnamic acid. This product can be directly oxidized to produce 4-Hydroxybenzoic acid and reduction to produce 4-Hydroxybenzyl alcohol.
Definition
ChEBI: 4-coumaric acid is a coumaric acid in which the hydroxy substituent is located at C-4 of the phenyl ring. It has a role as a plant metabolite. It is a conjugate acid of a 4-coumarate.
Hazard
Moderately toxic.
Sicherheitsprofil
Moderarely toxic by
intraperitoneal route. Experimental
reproductive effects. When heated to
decomposition it emits acrid smoke and
fumes. See also COUMARIN
4-Hydroxyzimtsure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-Hydroxyzimtsure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 461)Lieferanten
7400-08-0(4-Hydroxyzimtsure)Verwandte Suche:
- beta-(4-hydroxyphenyl)acrylicacid
- beta-[4-Hydroxyphenyl]acrylic acid
- Cinnamic acid, p-hydroxy-
- para-Coumaric acid
- p-hydroxy-cinnamicaci
- p-Hydroxyphenylacrylic acid
- p-hydroxyphenylacrylicacid
- P-HydroxycinnnamicAcid
- 4-Hydroxycinamicacid
- RARECHEM BK HW 0163
- P-HYDROXYL CINNAMIC ACID
- Alkaline ceramidase
- Anti-PHCA antibody produced in rabbit
- ACER3
- Alkaline CDase 3
- Alkaline ceramidase 3
- Alkaline dihydroceramidase SB89
- Alkaline phytoceramidase
- AlkCDase 3
- ANTI-ACER3 (C-TERM) antibody produced in rabbit
- APHC
- LABOTEST-BB LT00452637
- COUMARIC ACID, TRANS-P-
- AKOS 221-47
- AKOS BAR-2479
- 3-(4-hydroxyphenyl)-2-propenoicaci
- 3-(4-hydroxyphenyl)-2-Propenoicacid
- 2-Propenoic acid, 3-(4-hydroxyphenyl)-
- PARA-HYDROXYCINNAMICACID
- PARA-OH-CINNAMICACID
- 3-(4-Hydroxyphenyl)acrylic acid, tech
- NSC 59260
- NSC 674321
- 4-HYDROXYCINNAMIC ACID FOR SYNTHESIS
- 4-Hydroxybenzeneacrylic acid
- 4-HydroxycinnaMicAcid,Mixtureofcisandtrans
- Liposomal Hydroxycinnamic Acid, Water Soluble Hydroxycinnamic Acid, Hydroxycinnamic Acid NanoEmulsion
- Naringeninic ac
- 4-Hydroxycinnamic acid 98%
- 4-coumaricaci
- 4-HYDROXYCINNAMIC ACID CAS:7400-08-0
- p-Hydroxy-cinnamic acid USP/EP/BP
- p-Hydroxy-cinnamic acid,4-Hydroxycinnamic Acid,2-Propenoic acid, 3-(4-hydroxyphenyl)-
- TRANS-4-COUMARIC ACID
- TRANS-P-CUMARIC ACID
- TRANS-P-COUMARIC ACID
- PHCA
- P-HYDROXYCINNAMIC ACID
- P-CUMARIC ACID
- 4-hydroxylcinnamic acid
- 3-(4-HYDROXYPHENYL)ACRYLIC ACID
- (2E)-3-(4-Hydroxyphenyl)-2-propenoic acid
- 3-(4-Hydroxyphenyl)-2-propenoic acid
- 4-Hydroxycinnamic acid
- 3-(4-Hydroxyphenyl)propenoic acid
- 4-Hydroxycinnamic acid
- 4-Hydroxycinnamic acid
- Esmolol Impurity 51
