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Thienamycin

Thienamycin Struktur
59995-64-1
CAS-Nr.
59995-64-1
Englisch Name:
Thienamycin
Synonyma:
Imipenem EP Impurity A;(+)-Thienamycin;Thienamycin (>80%);IMipeneM IMpurity A;Thienamycin USP/EP/BP;Imipenemum Impurity A;(3As,7As)-Octahydro-2-benzofuran;Imipenem Impurity 1(Imipenem EP Impurity A);(5R)-3-(2-Aminoethylthio)-6β-[(R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hepta-2-ene-2-carboxylic acid;(5R)-3-[(2-Aminoethyl)thio]-6β-[(R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
CBNumber:
CB8969644
Summenformel:
C11H16N2O4S
Molgewicht:
272.32
MOL-Datei:
59995-64-1.mol

Thienamycin Eigenschaften

alpha 
D27 +82.7° (c = 1.0 in water)
Siedepunkt:
514.0±50.0 °C(Predicted)
Dichte
1.50±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -86°C Freezer, Under inert atmosphere
L?slichkeit
Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
Aggregatzustand
Solid
pka
4.20±0.40(Predicted)
Farbe
Off-White to Dark Yellow
Stabilit?t:
Hygroscopic, Temperature Sensitive, Very Unstable
InChI
InChI=1S/C11H16N2O4S/c1-5(14)8-6-4-7(18-3-2-12)9(11(16)17)13(6)10(8)15/h5-6,8,14H,2-4,12H2,1H3,(H,16,17)/t5-,6-,8-/m1/s1
InChIKey
WKDDRNSBRWANNC-ATRFCDNQSA-N
SMILES
N12[C@@]([H])([C@@H]([C@H](O)C)C1=O)CC(SCCN)=C2C(O)=O

Sicherheit

Thienamycin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Thienamycin, one of the most potent naturally-produced antibiotics known thus far, was discovered in Streptomyces cattleya in 1976. Thienamycin has excellent activity against both Gram-positive and Gram-negative bacteria and is resistant to bacterial β-lactamase enzymes.

Verwenden

Thienamycin is one of the most potent naturally produced antibiotics known thus far. It has excellent activity against both Gram-positive and Gram-negative bacteria and is resistant to bacterial β-lactamase enzymes.

Thienamycin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Autolyzed yeast Phosphate Buffer solution Stickstoff Glucose Polyethylene Glycol

Downstream Produkte

Thienamycin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 75)Lieferanten
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59995-64-1()Verwandte Suche:

  • [SR-[5α，6α(R^<*>^)]]-3-[(2-Aminoethyl)thio]-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • (5R)-3-(2-Aminoethylthio)-6β-[(R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hepta-2-ene-2-carboxylic acid
  • (5R)-3-[(2-Aminoethyl)thio]-6β-[(R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • (5R,6R)-3-(2-aminoethylsulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • (5R,6R)-3-(2-aminoethylthio)-6-[(1R)-1-hydroxyethyl]-7-keto-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • (5R,6R)-3-(2-azanylethylsulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • IMipeneM IMpurity A
  • Imipenem Impurity 1(Imipenem EP Impurity A)
  • (5R,6S)-3-(2-aminoethylthio)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[(2-aminoethyl)thio]-6-[(1R)-1-hydroxyethyl]-7-oxo-, (5R,6S)-
  • (3As,7As)-Octahydro-2-benzofuran
  • Thienamycin USP/EP/BP
  • Thienamycin (>80%)
  • Imipenem EP Impurity A
  • (+)-Thienamycin
  • Imipenemum Impurity A
  • 59995-64-1
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