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Emedastine

Emedastine Struktur
87233-61-2
CAS-Nr.
87233-61-2
Englisch Name:
Emedastine
Synonyma:
EMEDASTINE;Emedastine impurity F;Emedastinc Impurity C;Emedastine Impurity C;Emedastine Impurity 14;1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)benzimidazole;1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzimidazole;1-(2-ethoxyethyl)-2-(4-Methyl-1,4-diazepan-1-yl)-1H-1,3-benzodiazole;1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzo[d]imidazole;1-(2-Ethoxyethyl)-2-(4-methylhexahydro-1H-1,4-diazepine-1-yl)-1H-benzimidazole
CBNumber:
CB8728076
Summenformel:
C17H26N4O
Molgewicht:
302.41
MOL-Datei:
87233-61-2.mol

Emedastine Eigenschaften

Siedepunkt:
446.6±55.0 °C(Predicted)
Dichte
1.15±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
DMSO: 125 mg/mL (413.35 mM); Ethanol: 100 mg/mL (330.68 mM)
pka
8.86±0.10(Predicted)
Aggregatzustand
Viscous Liquid
Farbe
Yellow to brown
CAS Datenbank
87233-61-2(CAS DataBase Reference)

Sicherheit

Emedastine Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Antihistaminic, H1-receptor; asthma prophylactic; anti-allergic.

Definition

ChEBI: 1-Methyl-1,4-diazepane in which the hydrogen attached to the nitrogen at position 4 is substituted by a 1-(2-ethoxyethyl)-1H-benzimidazol-2-yl group. A relatively selective histamine H1 antagonist, it is used as the ifumatate salt for allergic rhinitis, urticaria, and pruritic skin disorders, and in eyedrops for the symptomatic relief of allergic conjuntivitis.

Clinical Use

Emedastine also is a newer antihistamine used topically in the eye for conjunctivitis. It has very high H1 receptor selectivity characteristics, and it is structurally related to the benzimidazoles, such as astemizole. Inhibition of mast cell release of inflammatory mediators has been noted.

Emedastine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

N-(2-ETHOXY-ETHYL)-BENZENE-1,2-DIAMINE (2-ETHOXY-ETHYL)-(2-NITRO-PHENYL)-AMINE EMEDASTINE IMPURITY E 1-(2-ETHOXY-ETHYL)-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE 1H-BENZIMIDAZOLE,2-CHLORO-1-(2-ETHOXYETHYL) 1-Boc-hexahydro-1,4-diazepine N-Methylhomopiperazine 2-Chlor-1H-benzimidazol Anilin Formaldehyd 1-Chlor-2-nitrobenzol

Downstream Produkte

Emedastine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 89)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714
 fandachem@gmail.com China 9218 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32820 60
Hubei Jusheng Technology Co.,Ltd. 		18871490254
linda@hubeijusheng.com CHINA 28172 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 49374 58
career henan chemical co 		+86-0371-86658258 +8613203830695
 factory@coreychem.com China 29815 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32002 58
Hefei Hirisun Pharmatech Co., Ltd 		+8615056975894
 shawn@hirisunpharm.com CHINA 9911 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471
 sales@sarms4muscle.com China 10473 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +8618949823763
 sales@tnjchem.com China 25356 58

87233-61-2()Verwandte Suche:

  • EMEDASTINE
  • 1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)benzimidazole
  • 1-(2-Ethoxyethyl)-2-(4-methylhexahydro-1H-1,4-diazepine-1-yl)-1H-benzimidazole
  • 1-(2-Ethoxyethyl)-2-[(hexahydro-4-methyl-1H-1,4-diazepin)-1-yl]-1H-benzimidazole
  • 1-(2-ethoxyethyl)-2-(4-Methyl-1,4-diazepan-1-yl)-1H-1,3-benzodiazole
  • 1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzimidazole
  • 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzo[d]imidazole
  • Emedastine impurity F
  • allergic,Histamine Receptor,antiallergic,benzimidazole,Inhibitor,skin,inhibit,Emedastine,orally,rhinitis,diseases,conjunctivitis
  • Emedastine Impurity 14
  • Emedastine Impurity C
  • Emedastinc Impurity C
  • 87233-61-2
  • C17H26N4O
  • impurity
  • DCP
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