Teprenone
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- CAS-Nr.
- 6809-52-5
- Englisch Name:
- Teprenone
- Synonyma:
- geranylgeranylacetone;Selbex;eprenone;TEPRENONE;Tepronone;Teprenone RS;UNII-S8S8451A4O;Teprenone, >=98%;Tetraprenylacetone;All trans-Teprenone
- CBNumber:
- CB8386175
- Summenformel:
- C23H38O
- Molgewicht:
- 330.55
- MOL-Datei:
- 6809-52-5.mol
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Teprenone Eigenschaften
- Siedepunkt:
- bp0.01 155-160°
- Dichte
- d420.5 0.9081
- Brechungsindex
- nD20 1.4947
- storage temp.
- -20°C
- L?slichkeit
- DMSO: >5mg/mL
- Aggregatzustand
- liquid
- Farbe
- clear
- Merck
- 14,9228
- Stabilit?t:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
- InChIKey
- SBOCYPUKNYDTSX-DMLVRTFPSA-N
- LogP
- 8.200 (est)
- CAS Datenbank
- 6809-52-5(CAS DataBase Reference)
Teprenone Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Teprenone (geranylgeranylacetone) is an antiulcer agent whose synthesis was
inspired by the gastric protecting properties of Coenzyme Q10. Teprenone is
reported to act via enhancement of gastric mucosal glycoprotein secretion.
Chemische Eigenschaften
Yellow Oil
Verwenden
An anti-ulcerative. Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as inflammatory bowel disease, hypoxic/ischemic brain injury and spinal and bulbar muscular atrophy (cytoprotective and anti-inflammatory effects). Reports indicate that GGA protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression. Other studies have shown that GGA induces expression of HSPB8 and HSPB1 and reduces the formation of amyloid oligomers as well as insoluble aggregates in HSPB5 R120G TG mice.
Definition
ChEBI: A terpene ketone in which a (9E,13E)-geranylgernayl group is bonded to one of the alpha-methyls of acetone (it is a mixture of 5E- and 5Z-geoisomers in a 3:2 ratio).
Teprenone Upstream-Materialien And Downstream Produkte
Upstream-Materialien
BFYVSGCRUDETNO-JYQWTDEISA-N
Butanoic acid, 3-oxo-, (4E,8E)-1-ethenyl-1,5,9,13-tetramethyl-4,8,12-tetradecatrien-1-yl ester
GERANYL GERANYL BROMIDE
ethyl (4E,8E,12E)-2-acetyl-5,9,13,17-tetramethyloctadeca-4,8,12,16-tetraenoate
GERANYLGERANIOL
(E,E)-3,7,11,15-Tetramethylhexadeca-1,6,10,14-tetraen-3-ol
5-ACETYL-2,2-DIMETHYL-1,3-DIOXANE-4,6-DIONE
Downstream Produkte
Teprenone Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 190)Lieferanten
6809-52-5()Verwandte Suche:
Androst-4-en-3,17-dion
2-Propens?ure-2-methyl-2-propenylester
Gestrinone
3,4,5,6,9,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacy-clotetradecin-1,7(8H)-dion,(S-(E))-
Estr-4-en-3,17-dion
Methylcyclopentadien
Quinocetone
Cyclopentadien
3a,4,7,7a-Tetrahydro-4,7-methan-1H-inden
Clethodim
(Z)-2-Amino-α-(methoxyimino)thiazol-4-essigsure
Tetraphenylcyclopentadienon
(E,E)-6,10,14-Trimethylpentadeca-5,9,13-trien-2-on
(E)-6,10-Dimethylundeca-5,9-dien-2-on
- 6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraen-2-one
- TEPRENONE
- 13,17-nonadecatetraen-2-one,6,10,14,18-tetramethyl-9
- 6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one
- Selbex
- Tetraprenylacetone
- Teprenone(mixture of isomers)
- Teprenone [mixture of (5E,9E,13E)- and (5Z,9E,13E)- isomers]
- 6,10,14,18-TetraMethyl-
- Geranylgeranylacetone
6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one
- 5,9,13,17-Nonadecatetraen-2-one,6,10,14,18-tetraMethyl-
- 6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one, mixture of (5E,9E,13E) and (5Z,9E,13E) isomers
- UNII-S8S8451A4O
- Teprenone, >=98%
- Teprenone (trans,trans)
- All trans-Teprenone
- (5Z,9Z,13Z)-6,10,14,18-tetramethyl-2-nonadeca-5,9,13,17-tetraenone
- Teprenone RS
- Teprenone USP/EP/BP
- 6,10,14,18-Tetramethylnonadeca-5,9,13,17-tetraen-2-one
- TeprenoneQ: What is
Teprenone Q: What is the CAS Number of
Teprenone Q: What is the storage condition of
Teprenone Q: What are the applications of
Teprenone
- NanoLiposomal Teprenone , Water-Soluble Teprenone
- geranylgeranylacetone
- eprenone
- Teprenone（Z/Emixture）
- Teprenone, mixture of (5E,9E,13E)- and (5Z,9E,13E)- isomers，≥ 95.0%
- Tepronone
- 6809-52-5
- 2C23H38O
- Aliphatics
- Intermediates & Fine Chemicals
- Pharmaceuticals
- 6809-52-5
