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2',5'-Dihydroxyacetophenon

2',5'-Dihydroxyacetophenone Struktur
490-78-8
CAS-Nr.
490-78-8
Bezeichnung:
2',5'-Dihydroxyacetophenon
Englisch Name:
2',5'-Dihydroxyacetophenone
Synonyma:
2,5-DIHYDROXYACETOPHENONE;1-(2,5-DIHYDROXYPHENYL)ETHAN-1-ONE;1-(2,5-DIHYDROXYPHENYL)ETHANONE;Ethanone, 1-(2,5-dihydroxyphenyl)-;2-hydroxy-1-(3-hydroxyphenyl)ethan-1-one;2,5-DHAP;ACETYLQUINOL;WLN: QR CQ BV1;QUINACETOPHENONE;Acetylhydroquinone
CBNumber:
CB8221168
Summenformel:
C8H8O3
Molgewicht:
152.15
MOL-Datei:
490-78-8.mol

2',5'-Dihydroxyacetophenon Eigenschaften

Schmelzpunkt:
204-206 °C(lit.)
Siedepunkt:
234.6°C (rough estimate)
Dichte
1.2143 (rough estimate)
Brechungsindex
1.4447 (estimate)
storage temp. 
Store below +30°C.
L?slichkeit
dioxane: 50 mg/mL, clear
pka
9.86±0.18(Predicted)
Aggregatzustand
Crystals or Crystalline Powder
Farbe
Yellow to yellow-green
Wasserl?slichkeit
insoluble
BRN 
637903
InChIKey
WLDWSGZHNBANIO-UHFFFAOYSA-N
LogP
1.274 (est)
CAS Datenbank
490-78-8(CAS DataBase Reference)
NIST chemische Informationen
Ethanone, 1-(2,5-dihydroxyphenyl)-(490-78-8)
EPA chemische Informationen
Ethanone, 1-(2,5-dihydroxyphenyl)- (490-78-8)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38
S-S?tze: 26-36
WGK Germany  3
RTECS-Nr. AM7700000
Hazard Note  Irritant
TSCA  Yes
HS Code  29145000
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P304+P340 BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

2',5'-Dihydroxyacetophenon Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Beschreibung

2',5'-Dihydroxyacetophenone is a natural phenolic compound that is found in many plants. It has been shown to have anti-inflammatory properties through its ability to inhibit the production of pro-inflammatory cytokines, such as tumor necrosis factor alpha and interleukin 1 beta.

Chemische Eigenschaften

yellow to yellow-green crystals or

Verwenden

2',5'-Dihydroxyacetophenone is an intermediate used in various synthetic preparations of pharmaceutical goods, 1-(2,5-Dihydroxyphenyl)ethanone was untilized in the synthesis of new flavonoid fatty acid esters with anti-adipogenic and glucose consumption enhancing activities.

Application

2',5'-Dihydroxyacetophenone inhibits the formation of reactive oxygen species and nitric oxide in rat neutrophils. It also has the ability to reduce oxidative stress by scavenging free radicals and inhibiting lipid peroxidation. The underlying mechanism for these effects is not fully understood but may be due to its ability to act as a substrate for matrix-assisted laser desorption ionization (MALDI). This means that it can react with protocatechuic acid molecules that are present in the sample preparation chamber, leading to polymerase chain reaction (PCR) amplification.

synthetische

Preparation by Fries rearrangement of hydroquinone diacetate,
with aluminium chloride(91%) (76%)(63–77%) (55–60%)
with zinc chloride in refluxing acetic acid (quantitative yield)
with boron trifluoride etherate in benzene at reflux (65%).

2',5'-Dihydroxyacetophenon Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


2',5'-Dihydroxyacetophenon Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 385)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Changzhou Ditong Chemical Co.,Ltd
+86-0519-88299272
info@edengenechem.com China 2158 58
Xi'an Yutbon Pharmaceutical Technology Co., Ltd
029-81140587 +8618717328141
sales@yutbon.com China 454 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29793 60
Hebei Weibang Biotechnology Co., Ltd
+8615531157085
abby@weibangbio.com China 8806 58
Hebei Mujin Biotechnology Co.,Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12831 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
sales1@chuanghaibio.com China 5889 58
Hebei Zhuanglai Chemical Trading Co Ltd
+86-16264648883 +86-16264648883
niki@zlchemi.com China 3567 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886
info@dakenam.com China 18940 58
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29879 58
Zhejiang ZETian Fine Chemicals Co. LTD
+8618957127338
stella@zetchem.com China 2136 58

490-78-8(2',5'-Dihydroxyacetophenon)Verwandte Suche:


  • 1-(2,5-dihydroxyphenyl)-ethanon
  • 1-Acetyl-2,5-dihydroxybenzene
  • 2,5-Dihydroxy-1-acetylbenzene
  • 2’,5’-dihydroxy-acetophenon
  • Acetophenone, 2',5'-dihydroxy-
  • Acetylhydroquinone
  • QUINACETOPHENONE
  • 2-Acetylhydroquinone Quinacetophenone
  • 2',5'-DIHYDROXYACETOPHENONE FOR SYNTHESI
  • 1-(2,5-Dihydroxyphenyl)ethan-1-one, 2-Acetylhydroquinone
  • 2,5- twohydroxyAcetophenone
  • WLN: QR CQ BV1
  • ACETYLQUINOL
  • 2,5-DIHYDROXYPHENYL METHYL KETONE
  • 2',5'-DIHYDROXYACETOPHENONE
  • 2-ACETYL-1,4-DIHYDROXYBENZENE
  • 2-ACETYLHYDROQUINONE
  • 2',5'-Dihydroxyacetophenone 2-Acetylhydroquinone
  • 2,5-Dihydroxyacetophenone, 98+%
  • 2-Acethylhydroquinone
  • 2,5-DIHYDROXYACETOPHENONE extrapure
  • 2,5-Dihydroxyphenyl methyl ketone, 2-Acetyl-1,4-dihydroxybenzene, 2-Acetylhydroquinone, Acetylquinol, Quinacetophenone
  • 2',5'-Dihydroxyacetophenone,97%
  • 2',5'- Dihydroxyacetophnone
  • 2′,5′-Dihydroxyacetophenone,2,5-Dihydroxyphenyl methyl ketone, 2-Acetyl-1,4-dihydroxybenzene, 2-Acetylhydroquinone, Acetylquinol, Quinacetophenone
  • 2',5'-Dihydroxyaceto
  • 2 ', 5'-hydroxyacetophenone
  • 5'-Dihydroxyacetophenone
  • 2',5'-Dihydroxyacetophenone>
  • 2,5-DHAP
  • 2,5-Dihydroxy-Acetophenone (Quinacetophenone -98 %)
  • 2,5-DIHYDROXYACETOPHENONE
  • 1-(2,5-DIHYDROXYPHENYL)ETHAN-1-ONE
  • 1-(2,5-DIHYDROXYPHENYL)ETHANONE
  • Ethanone, 1-(2,5-dihydroxyphenyl)-
  • 2-hydroxy-1-(3-hydroxyphenyl)ethan-1-one
  • 2',5'- Di hyfeoxy acetophenone
  • 2',5'-Dihydroxyacetophenone(Quinactophenone)
  • 2',5'-Dihydroxyacetophenone, ≥ 98.0%
  • 2',5'-Dihydroxyacetophenone
  • 2',5'-Dihydroxyacetophenone(Quinactophenone)
  • 2,5-Dihydroxyacetophenone, 10 mM in DMSO
  • 490-78-8
  • 490-78-9
  • HO2C6H3COCH3
  • BioChemical
  • Building Blocks
  • C7 to C8
  • Carbonyl Compounds
  • Mass Spectrometry
  • Matrices for MALDI Analysis
  • Ketones
  • Organic Building Blocks
  • Protein Analysis
  • Proteomics and Protein Expression
  • KETONE
  • Building Blocks
  • C7 to C8
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