O-ALLYLHYDROXYLAMINE HYDROCHLORIDE
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- CAS-Nr.
- 38945-21-0
- Englisch Name:
- O-ALLYLHYDROXYLAMINE HYDROCHLORIDE
- Synonyma:
- (Allyloxy)amine hydrochloride;O-ALLYHYDROXYAMINE HYDROCHLORIDE);O-ALLYLHYDROXYLAMINE HYDROCHLORIDE;3-(Aminooxy)prop-1-ene hydrochloride;O-Allylhydroxylamine Hydrochloride >O-prop-2-enylhydroxylamine hydrochloride;O-(2-PROPENYL)HYDROXYLAMINE HYDROCHLORIDE;O-Allylhydroxylamine Hydrochloride;HydroxylaMine, O-2-propenyl-, hydrochloride;O-Allylhydroxylamine hydrochloride >=98.0% (AT)
- CBNumber:
- CB7738618
- Summenformel:
- C3H8ClNO
- Molgewicht:
- 109.55
- MOL-Datei:
- 38945-21-0.mol
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O-ALLYLHYDROXYLAMINE HYDROCHLORIDE Eigenschaften
- Schmelzpunkt:
- ~170 °C (dec.)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Aggregatzustand
- powder to crystal
- Farbe
- White to Almost white
- BRN
- 3552394
- InChIKey
- XIQUJVRFXPBMHS-UHFFFAOYSA-N
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xi |
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| R-S?tze: |
36/37/38 |
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| S-S?tze: |
26-36 |
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| WGK Germany |
3 |
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| F |
3-9 |
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| HS Code |
2928009090 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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O-ALLYLHYDROXYLAMINE HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
synthetische
To a solution of 86.8 gm (1.55 moles) of potassium hydroxide in 330 ml of absolute ethanol is added a solution of 159 gm (1.52 moles) of ethyl N-hydroxycarbamate in 330 ml of absolute ethanol. With external cooling to maintain an internal temperature of 25°C to this mixture is added 195.5 gm (1.62 moles) of allyl bromide. After the addition has been completed, the mixture is heated under reflux for 2 hr. After separating the potassium bromide formed during the reaction and washing it with absolute alcohol, the alcoholic solution is evaporated under reduced pressure. The residue is dissolved in ether and then the ether solution is extracted repeatedly with 10% aqueous sodium hydroxide solution. [From the ether solution, on evaporation 25.5 gm (18%) of ethyl N,O-diallylhydroxycar-bamate, b.p. 91-92°C (8.55 mm Hg) may be isolated.] The aqueous extract is acidified with 10% aqueous sulfuric acid and the ethyl O-allylhy-droxycarbamate is extracted with ether. Upon evaporating the ether off, 134.2 gm (61%) of the intermediate product, b.p. 107°C (12.5 mm Hg), is isolated.
In a steam distillation apparatus, 134 gm of ethyl O-allylhydroxy-carbamate is treated with a solution of 120 gm of potassium hydroxide in 280 ml of water. The product is steam-distilled into a receiver containing dilute hydrochloric acid.
The steam distillate is evaporated under reduced pressure. The residue is taken up twice in absolute ethanol and dried by evaporation under reduced pressure. The yield is 91 gm (55%, overall), m.p. 169-170°C. Upon recrystallization from absolute alcohol and dry ether, the melting point is raised to 170.6-170.8°C (172-174°C). Free O-allylhydrox-ylamine has the following reported properties: b.p. 98-99°C, n
25D 1.4300.
The problems connected with the preparation of O-arylhydroxylamines by this method have been attributed to the instability of the aryl- substituted aminooxy group to the hydrolytic system used in its preparation. This problem has recently been circumvented by substituting for ethyl N-hydroxycarbamate, t-butyl N-hydroxycarbamate.
O-ALLYLHYDROXYLAMINE HYDROCHLORIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
O-ALLYLHYDROXYLAMINE HYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 129)Lieferanten
38945-21-0()Verwandte Suche:
- O-ALLYLHYDROXYLAMINE HYDROCHLORIDE
- O-(2-PROPENYL)HYDROXYLAMINE HYDROCHLORIDE
- O-ALLYHYDROXYAMINE HYDROCHLORIDE)
- O-Allylhydroxylamine hydrochloride >=98.0% (AT)
- O-prop-2-enylhydroxylamine hydrochloride
- Hydroxylamine, O-2-propenyl-, hydrochloride (9CI)
- O-Allylhydroxylamine Hydrochloride
- HydroxylaMine, O-2-propenyl-, hydrochloride
- (Allyloxy)amine hydrochloride
- 3-(Aminooxy)prop-1-ene hydrochloride
- O-Allylhydroxylamine Hydrochloride >
- (O-(prop-2-en-1-yl)hydroxylamine hydrochloride).
- 38945-21-0
- C3H7ONHCl
- C3H8ClNO
- CH2CHCH2ONH2HCl
- Building Blocks
- Hydroxylamines (O-Substituted)
- Hydroxylamines
- Nitrogen Compounds
- Organic Building Blocks
- Hydroxylamines (O-Substituted)
- Hydroxylamines
