5,5'-(3-Carboxy-4-oxocyclohexa-2,5-dienylidenmethylen)disalicylsure
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- CAS-Nr.
- 4431-00-9
- Bezeichnung:
- 5,5'-(3-Carboxy-4-oxocyclohexa-2,5-dienylidenmethylen)disalicylsure
- Englisch Name:
- AURINTRICARBOXYLIC ACID
- Synonyma:
- ATA;SKL331;e)-6-oxo-;aluminonfreeacid;TIMTEC-BB SBB005410;AURINTRICARBONIC ACID;aurintricarboxylicaci;LABOTEST-BB LT00080677;AURINTRICARBOXYLIC ACID;aurinetricarboxylic acid
- CBNumber:
- CB7463004
- Summenformel:
- C22H14O9
- Molgewicht:
- 422.34
- MOL-Datei:
- 4431-00-9.mol
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5,5'-(3-Carboxy-4-oxocyclohexa-2,5-dienylidenmethylen)disalicylsure Eigenschaften
5,5'-(3-Carboxy-4-oxocyclohexa-2,5-dienylidenmethylen)disalicylsure Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
deep red coarse crystalline powder
Verwenden
Aurintricarboxylic acid is employed as a powerful inhibitor of cellular processes, including apoptosis, that are dependent on the formation of protein-nucleic acid complexes. It binds to a FGF and reduces its angiogenic activity. Aurintricarboxylic Acid has been shown to inhibit apoptotic cell death in various cell types induced by a variety of factors. It Inhibits protein-nucleic acid interactions. It stimulates the tyrosine phosphorylation of MAP kinases.
Definition
ChEBI: A member of the class of quinomethanes that is 3-methylidene-6-oxocyclohexa-1,4-diene-1-carboxylic acid in which the methylidene hydrogens are replaced by 4-carboxy-3-hydroxyphenyl groups. The trisodium salt is the biological stain 'chrome violet CG' while
the triammonium salt is 'aluminon'.
l?uterung methode
The acid is dissolved in aqueous NaOH, NaHSO3 solution is added until the colour is discharged and then the tricarboxylic acid is precipitated with HCl. [Heisig & Lauer Org Synth Coll Vol I 54 1941, Beilstein 10 IV 4161]. Do not extract the acid with hot water because it softens, forming a viscous mass. Make a solution in aqueous NH3. Aluminon is the NH4 salt.
5,5'-(3-Carboxy-4-oxocyclohexa-2,5-dienylidenmethylen)disalicylsure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5,5'-(3-Carboxy-4-oxocyclohexa-2,5-dienylidenmethylen)disalicylsure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 133)Lieferanten
4431-00-9(5,5'-(3-Carboxy-4-oxocyclohexa-2,5-dienylidenmethylen)disalicylsure)Verwandte Suche:
2,4-Hexadienal, (E,E)-
Hexa-2,4-dien-1-ol
(E)-2-Methylpent-2-en-1-sure
m,α-Dimethylstyrol
Hexa-2,4-diensure
Triammonium-5,5'-(3-carboxylato-4-oxocyclohexa-2,5-dienylidenmethylen)disalicylat
5-Phenylpenta-2,4-diensure
5-Methylsalicylaldehyd
(E)-Pent-2-en-1-sure
(E)-Pent-2-en-1-ol
6-Hydroxy-m-toluylsure
5,5'-Methylendisalicylsure
2,4-Dimethylpenta-1,3-dien
1-Methylcyclohexa-1,4-dien
5,5'-(3-Carboxy-4-oxocyclohexa-2,5-dienylidenmethylen)disalicylsure
4-[Bis(p-hydroxyphenyl)methylen]cyclohexa-2,5-dien-1-on
4-Pentens?ure
Trinatrium-5,5'-(3-carboxylato-4-oxocyclohexa-2,5-dienylidenmethylen)di(salicylat)
- TIMTEC-BB SBB005410
- LABOTEST-BB LT00080677
- ATA
- 5,5-(3-carboxy-4-oxocyclohexa-2,5-dienylidenemethylene)di(salicylic acid)
- aurinetricarboxylic acid
- AURINTRICARBOXYLIC ACID FREE ACIDPRACTIC AL GRADE
- Aurintricarboxylic Acid (Ata)
- AURINTRICARBONIC ACID
- Aurintricarboxylic acid, tech., 85%
- 1-Oxo-4-[bis(3-carboxy-4-hydroxyphenyl)methylene]-2,5-cyclohexadiene-2-carboxylic acid
- 5,5'-[(3-Carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methylene]bis(2-hydroxybenzoic acid)
- Aurintricarboxylic acid,85%,tech.
- 5,5'-((3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)Methylene)bis(2-hydroxybenzoic acid)
- AURINTRICARBOXYLIC ACID
- 1,4-cyclohexadiene-1-carboxylicacid,3-(bis(3-carboxy-4-hydroxyphenyl)methylen
- 5-[(3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-benzoicaci
- aluminonfreeacid
- e)-6-oxo-
- 5,5'-((3-Carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)
- bis(2-hydroxybenzoic acid)
- Benzoic acid, 3,3'-[(3-carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methylene]bis[6-hydroxy-
- aurintricarboxylicaci
- Aurintricarboxylic Acids (Technical Grade)
- SKL331
- 5-[(3-carboxy-4-hydroxyphenyl)-(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-hydroxybenzoic acid
- Aurintricarboxylic Acid - CAS 4431-00-9 - Calbiochem
- ATA(Aurintricarboxylic acid)
- 5,5'-((3-Carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methylene)bis(2-hydroxybenzoic acid)
- Aurintricarboxylic acid (ATA), Apoptosis inhibitor
- Aurintricarboxylic acid, 10 mM in DMSO
- 4431-00-9
- C22H14O9
- DNA metabolism
- DNA Repair Regulators
- BioChemical
- Cell Signaling and Neuroscience
- Cell Biology
- Apoptosis and Cell Cycle
- Colours, Dyes, Indicators & Pigments
