Inosin
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- CAS-Nr.
- 58-63-9
- Bezeichnung:
- Inosin
- Englisch Name:
- Inosine
- Synonyma:
- RIBOXINE;(-)-INOSINE;(-)-Inosine;HXR;nosine;(2R,3R,4S,5R)-2-(6-hydroxy-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol;Ino;Atorel;Inosie;Selfer
- CBNumber:
- CB7161412
- Summenformel:
- C10H12N4O5
- Molgewicht:
- 268.23
- MOL-Datei:
- 58-63-9.mol
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Inosin Eigenschaften
- Schmelzpunkt:
- 222-226 °C (dec.) (lit.)
- alpha
- -49.2 º (c=1,H2O 18 ºC)
- Siedepunkt:
- 226 C (dec.)
- Dichte
- 1.3846 (rough estimate)
- Brechungsindex
- -52 ° (C=1, H2O)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- L?slichkeit
- H2O: 0.5 M, clear, colorless
- pka
- 13.24±0.70(Predicted)
- Aggregatzustand
- Crystalline Powder
- Farbe
- White
- PH
- 1.2;8.8
- Geruch (Odor)
- Odorless
- Wasserl?slichkeit
- 2.1 g/100 mL (20 ºC)
- maximale Wellenl?nge (λmax)
- 251 (pH 0);248.5 (pH 6);253 (pH 11)
- Merck
- 14,4975
- BRN
- 624889
- Stabilit?t:
- Hygroscopic
- InChIKey
- UGQMRVRMYYASKQ-PKJMTWSGSA-N
- LogP
- -1.970 (est)
- CAS Datenbank
- 58-63-9(CAS DataBase Reference)
- NIST chemische Informationen
- Inosine(58-63-9)
- EPA chemische Informationen
- Inosine (58-63-9)
Inosin Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
White crystalline powder
Occurrence
Inosine is a synthetic
Verwenden
Inosine has been used:
- as a medium supplement in nucleotide rescue experiments in pancreatic cancer cell lines.
- as a component in holidic (synthetic) medium and in larval two-choice preference assay.
- as a reference standard in mass spectroscopy.
Definition
ChEBI: A purine nucleoside in which hypoxanthine is attached to ribofuranose via a beta-N9-glycosidic bond.
Allgemeine Beschreibung
Inosine is a non-canonical nucleotide majorly present as monophosphate. It has ability to base pair with deoxythymidine, deoxyadenosine and deoxyguanosine. Incorporation of inosine in place of guanine modulates translational events. Inosine has antioxidant, anti-inflammatory and neuroprotective functionality. Inosine is prescribed as a therapeutic supplement for nerve injury, inflammation and oxidative stress. It modulates biological processes through adenosine receptors. Its enhances neurite outgrowth in depressive disorders via adenosine receptors. Inosine is also used for treating sepsis in infections.
l?uterung methode
(-)-Inosine forms anhydrous crystals from aqueous 80% EtOH but the dihydrate from H2O. [Beilstein 31 H 25, 26 III/IV 2087.]
Inosin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Inosin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 744)Lieferanten
58-63-9(Inosin)Verwandte Suche:
Purin-6(1H)-on
5-Amino-1-β-D-ribofuranosyl-1H-imidazol-4-carboxamid
Guanosin-5'-(dinatriumphosphat)
Hexanatriumnaphth[2',3':6,7]indolo[2,3-c]dinaphtho[2,3-a:2',3'-i]carbazol-5,10,15,17,22,24-hexylhexasulfat
2'-Desoxyinosin
5'-Inosinsure, 2'-Deoxy-, Dinatriumsalz
Inosin, Verbindung mit (2-Hydroxypropyl)dimethylammonium-p-acetamidobenzoat (1:3)
Inosin 5'-monophosphatdinatriumsalzhydrat
Guanosin, zyklisches 3',5'-(Hydrogen-phosphat), Mononatriumsalz
Inosin-2',3',5'-triacetat
2',3'-Isopropylideninosin
Inosin-5'-(tetrahydrogentriphosphat)
Inosin-5'-(trihydrogendiphosphat)
Guanosin, N-(1-Oxobutyl)-, zyklisches 3',5'-(Hydrogen-phosphat)-2'-butanoat, Mononatriumsalz
2',3'-O-Isopropyliden-5'-O-tritylinosin
Inosin-cyclisch-3',5'-(hydrogenphosphat)
3'-Guanylsure, Dinatriumsalz
Inosin
- Atorel
- beta-D-Ribofuranoside, hypoxanthine-9
- beta-Inosine
- Hypoxanthine D-riboside
- Hypoxanthine, 9-beta-D-ribofuranosyl-
- hypoxanthined-riboside
- hypoxanthinenucleoside
- Ino
- INO 495
- Inosie
- Oxiamin
- Panholic-L
- Pantholic-L
- Ribonosine
- Selfer
- Trophicardyl
- INOSINE
- HYPOXANTHINE-9-BETA-D-RIBOFURANOSIDE
- HYPOXANTHINE 9-D-RIBOFURANOSIDE
- HYPOXANTHINE RIBONUCLEOSIDE
- HYPOXANTHINE RIBOSIDE
- HYPOXANTHOSINE
- 9-BETA-RIBOFURANOSYLHYPOXANTHINE
- 9-BETA-D-RIBOFURANOSYLHYPOXANTHINE
- 9-B-D-RIBOFURANOSYLHYPOXANTHINE
- 9-[3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-3H-PURIN-6-ONE
- 9-((2R,3R,4S,5R)-3,4-DIHYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-1,9-DIHYDRO-PURIN-6-ONE
- 6-HYDROXYPURINE RIBOSIDE
- Inosine AJI92
- INOSINE SIGMAULTRA
- INOSINE, CRYSTALLIZED
- Inosine,FreeBase
- InosineForBiochemistry99%
- Inosine,>98%
- hypoxanthine-9-á-d-ribofuranoside
- B-INOSINE
- D-Inosine
- [1',2',3',4',5'-13C5]inosine
- Inosine, 97+%
- 132953-54-9
- 28861-88-3
- 4181-51-5
- 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-tetrahydrofuranyl]-3H-purin-6-one
- 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one
- 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-3H-purin-6-one
- C00294
- InChI=1/C10H12N4O5/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18/h2-4,6-7,1
- SMR000058316
- ZINC05127790
- 9-[(2S,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one
- INOSINE,REAGENT
- 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
- 1,9-Dihydro-9-β-D-ribofuranosyl-6H-purin-6-one
- 6H-Purin-6-one, 1,9-dihydro-9-β-D-ribofuranosyl-
- 9-β-D-Ribofuranosylhypoxanthine
- Hypoxanthine, 9-β-D-ribofuranosyl-
- Inosine (8CI, 9CI)
- NSC 20262