Naltrexone hydrochloride
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- CAS-Nr.
- 16676-29-2
- Englisch Name:
- Naltrexone hydrochloride
- Synonyma:
- ReVia;Depade;nih8503;en1639a;Nalorex;Antaxone;4-D-butyl;Ccris 1168;NSC 409767;Nalmefene-3
- CBNumber:
- CB7121465
- Summenformel:
- C20H24ClNO4
- Molgewicht:
- 377.87
- MOL-Datei:
- 16676-29-2.mol
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Naltrexone hydrochloride Eigenschaften
- Schmelzpunkt:
- 274-2760C
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: 50 mg/mL, clear, colorless
- Farbe
- White to Off-White
- Wasserl?slichkeit
- Soluble in water at 50mg/ml.
- Sensitive
- Light Sensitive
- Merck
- 13,6389
- BRN
- 3580333
- CAS Datenbank
- 16676-29-2(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22 |
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| S-S?tze: |
22-36 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
QD2160000 |
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| F |
8-10 |
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| HS Code |
2932.99.7000 |
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| Toxizit?t |
guinea pig,LD50,oral,1490mg/kg (1490mg/kg),Medicamentos de Actualidad. Vol. 21, Pg. 264, 1985. |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
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Naltrexone hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Naltrexone hydrochloride is a potent, long-acting, orally-effective narcotic
antagonist useful in the management of narcotic addiction.
Chemische Eigenschaften
White Crystalline Powder
Verwenden
Naltrexone hydrochloride has been used:
as an opioid antagonist, to analyse its effect on ethanol preference using Caenorhabditis elegans as a model.
to determine its effectiveness in reducing the preference for substance of abuse (SOA) like nicotine and cocaine using Caenorhabditis elegans as a model.
in the preparation of combinatorial drug, PXT3003 for treating Charcot-Marie-Tooth disease 1A (CMT1A) transgenic rat model Pmp22.
Biologische Aktivit?t
Opioid antagonist.
l?uterung methode
This narcotic antagonist has been purified by recrystallisation from MeOH and dried in air. The free base has m 168-170o after recrystallisation from Me2CO. [Cone et al. J Pharm Sci 64 618 1975, Gold et al. Med Res Rev 2 211 1982.]
Naltrexone hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Naltrexone hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 295)Lieferanten
16676-29-2()Verwandte Suche:
- N-CYCLOPROPYLMETHYL-14-HYDROXYDI-HYDROMORPHINONE HYDROCHLORIDE
- NALTREXONE HYDROCHLORIDE
- (5alpha)-17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride
- (5A)-17-(CYCLOPROPYLMETHYL)-4,5-EPOXY-3,14-DIHYDROMORPHINAN-6-ONE HYDROCHLORIDE
- 17-(cyclopropylmethyl)-4,5-alpha-epoxy-3,14-dihydroxy-morphinan-6-onehydroch
- 17-(cyclopropylmethyl)-4,5-alpha-epoxy-3,14-dihydroxy-morphinan-6-onhydr
- 17-(cyclopropylmethyl)-4,5-alpha-oxy-3,14-dihydoxy-morphinan-6-onhydrochlo
- 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-morphinan-6-onhydrochlor
- en1639a
- n-cyclopropylmethyl-noroxymorphonehydrochloride
- nih8503
- Antaxone, Celupan
- Nalorex
- NALTREXONEHYDROCHLORIDE,USP
- 17-(Cyclopropylmethyl)-4,5-alpha-epoxy-3,14-dihydroxy-morphinan-6-one hydrochloride
- Ccris 1168
- Depade
- Einecs 240-723-0
- Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-alpha-epoxy-3,14-dihydroxy-, hydrochloride
- Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-alpha-oxy-3,14-dihydoxy-, hydrochloride
- Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, hydrochloride, (5-alpha)-
- (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydromorphinan-6-onehydrochloride
- (5α)-17-(Cyclopropyl-Methyl-d3)-4,5-epoxy-3,14-dihydroxyMorphinan-6-one Hydrochloride
- Antaxone
- Morphinan-6-one,17-(cyclopropylMethyl)-4,5-epoxy-3,14-dihydroxy-, hydrochloride (1:1), (5a)-
- (5α)-17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-morphinan-6-one, hydrochloride (1:1)
- Naltrexone hydrochloride
(5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride
- Naltrexone HCl USP/EP
- (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one hydrochloride
- (5-alpha)-id
- HIC-A90670115
- Nalmefene-3
- Nalmefene Hydrochloride Impurit Ⅰ:Naltrexone hydrochloride
- Morphinan-6-one, 17-(cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxy-, hydrochloride
- Nalmefene Impurity C
- Naltrexone HCl,Naltrexone Hydrochloride
- Sodium Pentosan
- Naltrexone (hydrochloride) (CRM)
- LTREXONE HYDROCHLORIDE
- Nalbuphine Impurity 5
- Naltrexone hydrochloride CRS
- Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, hydrochloride (1:1), (5α)-
- Naltrexone hydrochloride USP/EP/BP
- (5α)-17-(CyclopropylMethyl)-4,5-epoxy-3,14-dihydroMorphinan-6-onehydrochloride
- Nalmefene Hydrochloride Impurit Ⅰ:Naltrexone hydrochloride
- 4-D-butyl
- Lironox 326
- NSC 409767
- ReVia
- Nalbuphine Impurity 5（Naltrexone hydrochloride、Nalfuranfine Impurity 8）
- Naltrexone hydrochloride in methanol
- 16676-29-2
- 16676-29-3
- C20H23NO4HCl
- C20H23NO4ClH
- C20H23NO4HClH2O
- Biochemicals and Reagents
- BioChemical
