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Prednisolon-21-(dinatriumphosphat)

Prednisolone phosphate sodium Struktur
125-02-0
CAS-Nr.
125-02-0
Bezeichnung:
Prednisolon-21-(dinatriumphosphat)
Englisch Name:
Prednisolone phosphate sodium
Synonyma:
PREDNISOLONE SODIUM PHOSPHATE;PREDNISONE SODIUM PHOSPHATE;codelsol;Pediapred;hydeltrasol;Prednisolone sodium phosphate CRS;optival;predsol;Ak-pred;Dojilon
CBNumber:
CB6725349
Summenformel:
C21H27Na2O8P
Molgewicht:
484.39
MOL-Datei:
125-02-0.mol

Prednisolon-21-(dinatriumphosphat) Eigenschaften

Schmelzpunkt:
>197°C (dec.)
alpha 
D25 +102.5°
storage temp. 
Inert atmosphere,Room Temperature
L?slichkeit
Freely soluble in water, very slightly soluble in ethanol (96 per cent).
Aggregatzustand
Solid
Farbe
White to Off-White
maximale Wellenl?nge (λmax)
243nm(MeOH)(lit.)
Merck 
14,7721
Stabilit?t:
Hygroscopic
CAS Datenbank
125-02-0(CAS DataBase Reference)
EPA chemische Informationen
Pregna-1,4-diene-3,20-dione, 11,17-dihydroxy-21-(phosphonooxy)-, disodium salt, (11.beta.)- (125-02-0)

Sicherheit

WGK Germany  3
RTECS-Nr. TU4153300
HS Code  2937290000

Prednisolon-21-(dinatriumphosphat) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Prednisolone is a synthetic analog of the natural glucocorticoid corticosterone that has anti-inflammatory and immunsuppressive actions. It avidly binds both glucocorticoid and mineralocorticoid receptors (Kis = 2.4 and 37 nM). Prednisolone Phosphate, prepared as the sodium salt, is a water-soluble ester of the poorly soluble parent molecule, prednisolone. It is rapidly hydrolyzed in vivo to the parent molecule when administered intravenously. In addition, when given orally, prednisolone phosphate is more readily absorbed than prednisolone, resulting in a higher effective blood concentration of prednisolone.

Chemische Eigenschaften

White or almost white, hygroscopic, crystalline powder.

Verwenden

antiinflammatory

Prednisolon-21-(dinatriumphosphat) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Natriumhydroxid Methansulfonylchlorid Natriumiodid Prednisolon Orthophosphorsure

Downstream Produkte

Prednisolon-21-(dinatriumphosphat) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 370)Lieferanten
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125-02-0(Prednisolon-21-(dinatriumphosphat))Verwandte Suche:

  • SODIUM PREDNISOLONE-21-PHOSPHATE
  • prednisolone phosphate sodium
  • PREDNISOLONE 21-PHOSPHATE, DISODIUM SALT
  • (11beta)-
  • 4-diene-3,20-dione,11-beta,17,21-trihydroxy-pregna-21-(dihydrogenphosphat
  • e),disodiumsalt
  • inflamase
  • optival
  • phortisolone
  • prednesol
  • prednisolone21-phosphatedisodium
  • prednisolonedisodiumphosphate
  • predsol
  • predsolan
  • pregna-1,4-diene-3,20-dione,11,17-dihydroxy-21-(phosphonooxy)-,disodiumsalt,
  • prozorin
  • sodiumprednisolonephosphate
  • solucort
  • Pregna-1,4-diene-3,20-dione, 11,17-dihydroxy-21-(phosphonooxy)-, disodium salt, (11.beta.)-
  • PREDNISOLONESODIUMPHOSPHATE,USP
  • Ak-pred
  • Dojilon
  • Hefasolon
  • Metreton
  • Pregna-1,4-diene-3,20-dione, 11,17-dihydroxy-21-(phosphonooxy)-, disodium salt, (11b)- (9CI)
  • Pregna-1,4-diene-3,20-dione, 11b,17,21-trihydroxy-, 21-(dihydrogen phosphate), disodium salt (7CI, 8CI)
  • Pregna-1,4-diene-3,20-dione, 11b,17,21-trihydroxy-, 21-phosphate, disodium salt (6CI)
  • Solu-Predalone
  • Prednisolone 21-sodium phosphate
  • Prednisolone phospha
  • prednisolone 21-(disodium phosphate)
  • PrednisoloneSodiumPhosphateBp/Usp/Ep
  • Prednisolone Series Base 50-24-8 / Phosphate
  • Prednisolone Sodium Phosphate (500 mg)
  • Prednisolone SodiuM Phosphate USP/EP
  • Prednisolone Phosphate (sodium salt)
  • Pregna-1,4-diene-3,20-dione, 11,17-dihydroxy-21-(phosphonooxy)-, disodium salt, (11β)-
  • disodium prednisolone 21-phosphate
  • (11b)-11,17-dihydroxy-21-(phosphonooxy)-pregna-1,4-diene-3,20-dione disodium salt
  • 1,4-PREGNADIEN-11-BETA, 17,21-TRIOL-3,20-DIONE 21-PHOSPHATE, DISODIUM SALT
  • disodium [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
  • )-6,9-Difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-3-oxoandrosta-1,4-diene-17-carboxylic Acid
  • -Hydroxy-17,20:20,21-bis(methylenedioxy)pregn-4-en-3-one Nitrite
  • )-21-Chloro-9-fluoro-11-hydroxy-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
  • )-9-Fluoro-11,21-dihydroxy-16-methyl-pregna-1,4,16-triene-3,20-dione
  • 17,21-Trihydroxy-16&alpha
  • -methyl-pregn-4-ene-3,20-dione 21-Acetate
  • 17,20&beta
  • 21-Tetrahydroxypregna-1,4-dien-3-one 21-Acetate
  • -Hydroxy-3-oxo-androsta-1,4-diene-17&beta
  • )-17-(Acetyloxy)-11-[4-(dimethylamino)phenyl]-3-hydroxy-19-norpregna-1,3,5(10)-trien-20-one-d3
  • 21-Tetrahydroxypregna-1,4-diene-3,20-dione-d3
  • )-11-Hydroxy-16-methyl-17,21-bis(1-oxoacetoxy)-pregna-1,4-diene-3,20-dione
  • 17,21-Trihydroxy-3,20-dioxo-cyclic-18,11-hemiacetal Pregn-4-en-18-al Triacetate
  • -methyl-17,20:20,21-bis(methylenedioxy)-pregn-4-en-3-one
  • )-11,17,21-Trihydroxy-pregna-1,4,8-triene-3,20-dione
  • -Hydroperoxy Dienogest
  • -methyl-17,20:20,21-bis(methylenedioxy)-pregn-1,4-dien-3-one
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