MOEXIPRIL HYDROCHLORIDE
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- CAS-Nr.
- 82586-52-5
- Englisch Name:
- MOEXIPRIL HYDROCHLORIDE
- Synonyma:
- CI-925;Perdix;SPM-925;Univasc;Fempress;RS-10085;RS-10085-197;MOEXIPRIL HYDROCHLORIDE;Moexipril HCl (RS-10085);Moexipril hydrochloride, >=99%
- CBNumber:
- CB6500845
- Summenformel:
- C27H35ClN2O7
- Molgewicht:
- 535.03
- MOL-Datei:
- 82586-52-5.mol
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MOEXIPRIL HYDROCHLORIDE Eigenschaften
- Schmelzpunkt:
- 141-1610C
- alpha
- D23 +34.2° (c = 1.1 in ethanol)
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: soluble32mg/mL
- Aggregatzustand
- powder
- Farbe
- White to off-white
- Wasserl?slichkeit
- H2O: 32mg/mL
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
N |
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| R-S?tze: |
50 |
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| S-S?tze: |
60 |
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| RIDADR |
UN 3077 9/PG 3 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
NW7174500 |
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| HS Code |
2933492250 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H400 |
Sehr giftig für Wasserorganismen. |
Kurzfristig (akut) gew?ssergef?hrdend |
Kategorie 1 |
Warnung |
![GHS hazard pictograms]() src="/GHS09.jpg" width="20" height="20" /> |
P273, P391, P501 |
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| Sicherheit |
| P273 |
Freisetzung in die Umwelt vermeiden. |
| P391 |
Verschüttete Mengen aufnehmen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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MOEXIPRIL HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R50:Sehr giftig für Wasserorganismen.
S-S?tze Betriebsanweisung:
S60:Dieses Produkt und sein Beh?lter sind als gef?hrlicher Abfall zu entsorgen.
Beschreibung
Moexipril hydrochloride is a novel ACE inhibitor first marketed in the U.S.A. for
the treatment of hypertension as a monotherapy and as a second-line therapy in
combination with diuretics or calcium antagonists. Like other ACE inhibitors, moexipril
is a prodrug that is converted in the liver to its diacid moexiprilat which is the active
agent. Moexipril displays a higher in vitro inhibitory potency to ACE than enalapril
although its effectiveness in reduction of blood pressure in hypertensive patients is
similar to that seen with enalapril. It is orally active with a rapid onset and prolonged
duration of action. Excellent tolerability has been reported. Moexipril is distinguished
by its lower cost than other marketed ACE inhibitors.
Chemische Eigenschaften
Crystalline Solid
Verwenden
Angiotensin converting enzyme (ACE) inhibitor; dimethoxy analog of quinapril
Hazard
Moderately toxic by ingestion.
Biologische Aktivit?t
Angiotensin-converting enzyme (ACE) inhibitor that is hydrolyzed in the liver to the active metabolite moexiprilat (IC 50 values are 2.1 and 2700 nM for moexiprilat and moexipril respectively). Antihypertensive; decreases mean blood pressure in the spontaneous hypertensive rat (SHR). Also blocks degradation of bradykinin into inactive metabolites.
MOEXIPRIL HYDROCHLORIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
MOEXIPRIL HYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 148)Lieferanten
82586-52-5()Verwandte Suche:
- (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride
- 2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylicacidhydrochloride
- 3-Isoquinolinecarboxylicacid,2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]aMino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-diMethoxy-,hydrochloride (1:1), (3S)-
- (3S)- 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid,hydrochloride (1:1)
- RS-10085
- Moexipril Hydrochloride (100 mg)
- Moexipril hydrochloride, >=99%
- (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenyl-d5-propyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic Acid Hydrochloride
- CI-925
- Fempress
- Perdix
- RS-10085-197
- SPM-925
- Univasc
- (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic Acid Hydrochloride
- (3S)-2-[(2S)-2-[[(1S)-1-carbethoxy-3-phenyl-propyl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride
- (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenyl-butan-2-yl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride
- MOEXIPRIL HYDROCHLORIDE
- UNIVASC;RS10085;RS 10085;RS-10085
- (3S)-2-[(2S)-2-[[(1S)-1-Ethoxycarbonyl-3-Phenyl-Propyl]Amino]Propanoyl]-6,7-Dimethoxy-3,4-Dihydro-1H-Isoquinoline-3-Carboxylic Acid Hydrochloride
- 2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid, hydrochloride
- MOEXIPRIL HYDROCHLORIDE USP/EP/BP
- (S)-2-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
- Moexipril HCl (RS-10085)
- (3S)-2-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan
-2-yl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetr
ahydroisoquinoline-3-carboxylic acid
hydrochloride
- Moexipril HydrochlorideQ: What is
Moexipril Hydrochloride Q: What is the CAS Number of
Moexipril Hydrochloride Q: What is the storage condition of
Moexipril Hydrochloride Q: What are the applications of
Moexipril Hydrochloride
- Moexipril Hydrochloride (1445426)
- orally active,Apoptosis,Ischemic brain injury,inhibit,hepatic disease,RS10085,Angiotensin-converting Enzyme (ACE),hydrochlorothiazide,essential hypertension,Moexipril hydrochloride,antihypertensive,moexiprilat,angiotensin II,cardiovascular disease,RS 10085,Inhibitor,hypertension,Moexipril
- Moexipril hydrochloride, 10 mM in DMSO
- 82586-52-5
- C27H34N2O7HCl
- C27H35N2O7Cl
- C27H35ClN2O7
- C27H34N2O7ClH
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