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1,3-Dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-2H-benzimidazol-2-one

1,3-Dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-2H-benzimidazol-2-one Struktur
924377-85-5
CAS-Nr.
924377-85-5
Englisch Name:
1,3-Dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-2H-benzimidazol-2-one
Synonyma:
GSK 1702934A;GSK-1702934A,GSK1702934A;1,3-Dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-2H-benzimidazol-2-one;2H-Benzimidazol-2-one, 1,3-dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-
CBNumber:
CB64902623
Summenformel:
C22H25N3O2S
Molgewicht:
395.52
MOL-Datei:
924377-85-5.mol

1,3-Dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-2H-benzimidazol-2-one Eigenschaften

Dichte
1.299±0.06 g/cm3(Predicted)
storage temp. 
RT
L?slichkeit
Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml with warming)
Aggregatzustand
solid
pka
11.98±0.30(Predicted)
Farbe
White
Stabilit?t:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.

Sicherheit

1,3-Dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-2H-benzimidazol-2-one Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

GSK 1702934A is a potent and selective TRPC3/6 activator (EC50 = 80 and 440 nM for TRPC3 and 6, respectively). Exhibits no activity at TRPV4, TRPA1, M1, M4, CaV1.2, hERG, NaV1.5, or CXCR5 receptors at concentrations <10 μmol/L. Induces TRPC3/6-currents in HEK293 cells transduced with recombinant human TRPC3/6. Directly activates TRPC channels through by-passing phospholipase-C signaling. Also induces calcium signals in HEK-TRPC6 cells (pEC50 = 6.6).

1,3-Dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-2H-benzimidazol-2-one Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1,3-Dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-2H-benzimidazol-2-one Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 16)Lieferanten
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TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
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Aladdin Scientific 		+1-+1(833)-552-7181
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BOC Sciences 16314854226
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Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9806 58
Hefei fuya biotechnology co. LTD 18096409024
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ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
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Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223;
 psaitong@jm-bio.com China 29774 58
TargetMol Chemicals Inc. 4008200310
 marketing@tsbiochem.com China 24644 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581
 sales@chemhifuture.com China 4988 58
Shanghai Easy CDMO Co.,Ltd 021-61734564
August@easycdmo.com China 10030 58

924377-85-5()Verwandte Suche:

  • 1,3-Dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-2H-benzimidazol-2-one
  • GSK 1702934A
  • GSK-1702934A,GSK1702934A
  • 2H-Benzimidazol-2-one, 1,3-dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-
  • 924377-85-5
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