4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
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- CAS-Nr.
- 99010-64-7
- Englisch Name:
- 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline
- Synonyma:
- cas 99010-64-7;Imiquimod USP RC C;Imiquimod Impurity-C;DesaMino ChloroiMiquiMod;1H-Imidazo[4,5-c]quinoline,;IMiquiMod Related CoMpound C;Imiquimod USP Related Compound C;4-Chloro-1-isobutyl-1H-imidazo[4,5-;1H-IMIDAZO[4,5-C]QUINOLINE, 4-CHLORO-1-(;4-CHLORO-1-ISOBUTYL-1H-IMIBENZO(4,5-C)QUINOLINE
- CBNumber:
- CB6449735
- Summenformel:
- C14H14ClN3
- Molgewicht:
- 259.73
- MOL-Datei:
- 99010-64-7.mol
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4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Eigenschaften
- Schmelzpunkt:
- 139-140 °C(Solv: isopropanol (67-63-0))
- Siedepunkt:
- 427.5±48.0 °C(Predicted)
- Dichte
- 1.29±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- L?slichkeit
- Chloroform (Sparingly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 3.15±0.30(Predicted)
- Farbe
- White to Off-White
- CAS Datenbank
- 99010-64-7(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Bildanzeige (GHS) |
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Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
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Sicherheit |
P261 |
Einatmen von Staub vermeiden. |
P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline is a chemical product that has been used as a photosynthetic activator in weed science and pest control. It has been shown to significantly increase the growth rate of wheat, soybean, and oilseed crops. It is also effective at controlling weeds by inhibiting their ability to produce chlorophyll, thereby preventing them from photosynthesizing. 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline has also been shown to be an effective herbicide for agricultural use.
Verwenden
Desamino Chloroimiquimod (Imiquimod USP Related Compound C) is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.
Synthese
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline is prepared by the reaction of 2-chloro-N
4-(2-methylpropyl)quinoline-3,4-diamine and orthoformic acid triethyl ester. The specific synthesis steps are as follows:
A suspension of 2-chloro-N4 -(2-methylpropyl)-3,4-quinolinediamine (35 g) and triethylorthoformate (52.3 g, 2.5 eq) was heated at 145° C. for 10 h, during which time ethanol was removed by distillation. The resulting mixture was cooled to room temperature and the solid was removed by filtration. The solid was dissolved in hydrochloric acid (100 mL, 4N). The resulting solution was added to a solution of sodium hydroxide. The precipitate was filtered and washed with water to afford the product 4-chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline in 92% yield.
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 180)Lieferanten
99010-64-7()Verwandte Suche:
- 4-CHLORO-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE
- 4-CHLORO-1-ISOBUTYL-1H-IMIDAZOBEN[4,5-C]QUINOLINE
- 1-[2-METHYLPROPYL]-1H-2-CHLOROIMIDAZO-[4,5-C]QUINOLINE
- 1H-IMIDAZO[4,5-C]QUINOLINE, 4-CHLORO-1-(2-METHYLPROPYL)
- 4-Chloro-1-(2-methylpropyl)-1H-imidazo-(4,5c)quinolinone
- 2-CHLORO-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINONE
- 1H-Imidazo[4,5-c]quinoline,
- 4-CHLORO-1-ISOBUTYL-1H-IMIBENZO(4,5-C)QUINOLINE
- 1H-Imidazo[4,5-c]quinoline, -chloro-1-(2-methylpropyl)-
- 1H-Imidazo[4,5-c]quinolinone,2-chloro-1-(2-methylpropyl)
- Imiquimod Related Compound C (25 mg) (4-Chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline)
- 1-H-IMIDAZO[4,5-C]QUINOLINONE,4-CHLORO-1-(2-METHYL PROPYL)
- IMiquiMod Related CoMpound C
- DesaMino ChloroiMiquiMod
- 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline###4-Chloro-1-(2-methylpropyl)-1H-imidazole[4,5-c]quinoline
- 1H-IMIDAZO[4,5-C]QUINOLINE, 4-CHLORO-1-(
- 4-chloro-1-(2-methylpropyl)imidazo[4,5-c]quinoline
- Imiquimod USP Related Compound C
- 4-Chloro-1-isobutyl-1H-imidazo[4,5-
- Imiquimod USP RC C
- Imiquimod Impurity 3 (Imiquimod Related Compound C)
- Imiquimod Impurity-C
- Imiquimod Related Compound C (4-Chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline) (1338346)
- 4-CHLORO-1-ISOBUTYL-1H-IMIDAZO (4,5'D)QUINOLINE
- cas 99010-64-7
- 4-CHLORO-1-ISOBUTYL-1H-IMIDAZO (4,5'D)QUINOLINE
- 99010-64-7
- C14H14ClN3
- Quinolines, Quinazolines and derivatives
- Intermediates of Imiquimod
- API intermediates