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1,3-Dihydroxyaceton

1,3-Dihydroxyacetone Struktur
96-26-4
CAS-Nr.
96-26-4
Bezeichnung:
1,3-Dihydroxyaceton
Englisch Name:
1,3-Dihydroxyacetone
Synonyma:
DIHYDROXYACETONE;1,3-dihydroxypropan-2-one;Dihyxal;Glycerone;Ketochromin;1,3-Dihydroxypropanone;1,3-DIHYDROXY-2-PROPANONE;2-Propanone, 1,3-dihydroxy-;Otan;Aliphatic ketone
CBNumber:
CB6306814
Summenformel:
C3H6O3
Molgewicht:
90.08
MOL-Datei:
96-26-4.mol

1,3-Dihydroxyaceton Eigenschaften

Schmelzpunkt:
75-80 °C
Siedepunkt:
107.25°C (rough estimate)
Dichte
1.1385 (rough estimate)
Dampfdruck
0.002-0.33Pa at 20-50℃
FEMA 
4033 | DIHYDROXYACETONE
Brechungsindex
1.4540 (estimate)
storage temp. 
Store at +2°C to +8°C.
L?slichkeit
>112.4 mg/mL in DMSO; >5.09 mg/mL in EtOH with ultrasonic
Aggregatzustand
powder
pka
12.45±0.10(Predicted)
Farbe
White
Geruch (Odor)
at 100.00 %. minty
Geruchsart
minty
Wasserl?slichkeit
>250 g/L (20 ºC)
JECFA Number
1716
Stabilit?t:
Stable. Combustible. Hygroscopic.
LogP
-1.95 at 20℃
Oberfl?chenspannung
68.85mN/m at 1g/L and 20℃
CAS Datenbank
96-26-4(CAS DataBase Reference)
NIST chemische Informationen
2-Propanone, 1,3-dihydroxy-(96-26-4)
EPA chemische Informationen
2-Propanone, 1,3-dihydroxy- (96-26-4)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
S-S?tze: 24/25
HS Code  29141900
Giftige Stoffe Daten 96-26-4(Hazardous Substances Data)
Toxizit?t CHROMELIN ? DIHYDROXYACETONE ? 1,3DIHYDROXYACETONE ? 1,3-DIHYDROXYPROPANONE ? DIHYXAL ? NSC-24343 ? OTAN ? OXATONE ? SOLEAL ? 2PROPANONE, 1,3-DIHYDROXY- ? TRIULOSE ? VITICOLOR
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P302+P352 BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.
P321 Besondere Behandlung
P332+P313 Bei Hautreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
P362 Kontaminierte Kleidung ausziehen und vor erneutem Tragen waschen.

1,3-Dihydroxyaceton Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.

Chemische Eigenschaften

white powder

Occurrence

A derivative of naturally occurring starch

Verwenden

1,3-Dihydroxyacetone can be used as artificial tanning agent.

Definition

ChEBI: Dihydroxyacetone is a ketotriose consisting of acetone bearing hydroxy substituents at positions 1 and 3. The simplest member of the class of ketoses and the parent of the class of glycerones. It has a role as a metabolite, an antifungal agent, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a ketotriose and a primary alpha-hydroxy ketone.

synthetische

1,3-dihydroxyacetone (DHA) is prepared by acetalization, oxidation, and hydrolysis of glycerol. Usually produced commercially from Bacillus macerans or Bacillus circulans fermentation of starch or starch hydrolysate

Allgemeine Beschreibung

Dihydroxyacetone (DHA) is a browning ingredient widely used in cosmetics such as sunless tanning formulations. It participates in a chemical staining reaction called Milliard reaction in which it reacts with the amino groups of proteins to result in a mixture of high molecular weight pigments.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Sicherheitsprofil

Mutation data reported. When heated to decompositionit emits acrid smoke and irritating vapors.

Sicherheit(Safety)

Cells that were treated with 1,3-Dihydroxyacetone (DHA) showed dose- and time-dependent changes that included cytoplasmic budding, chromatin condensation, and cell detachment. There was a significant decrease in cell proliferation after 24 hours of DHA exposure. After exposure to a 5% DHA solution for 21 days, epidermal thickening and dermatitis of the skin were noted in laboratory animals. After 42 days of treatment with the same solution, hyperplastic and dyskeratotic changes and moderate inflammatory reactions were seen. Long-lasting topical tanning products contain the sugars DHA or erythrulose, which cause a "Maillard reaction" when contacting proteins in the outer layers of the stratum corneum and epidermis. This reaction happens when free amino acids from skin proteins combine with DHA in the stratum corneum. This combination creates the tanned appearance of skin. Results are generally seen within a few hours of application. UV light exposure is not needed to initiate this chemical reaction[1].

1,3-Dihydroxyaceton Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


1,3-Dihydroxyaceton Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 565)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651
admin@zlchemi.com China 3002 58
CD Chemical Group Limited
+8615986615575
info@codchem.com China 20342 58
Hebei Weibang Biotechnology Co., Ltd
+8617732866630
bess@weibangbio.com China 18148 58
Hebei Kingfiner Technology Development Co.Ltd
+86-15532196582 +86-15373005021
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Shanghai Likang New Materials Co., Limited
+86-16631818819 +86-17736933208
3684455296@qq.com China 9300 58
Hebei Weibang Biotechnology Co., Ltd
+8615350571055
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ZhenYiBio Technology Inc
+8615309206328
alexxue@zhenyibio.com China 296 58
Hebei Weibang Biotechnology Co., Ltd
+8615531157085
abby@weibangbio.com China 8806 58
Hebei Yanxi Chemical Co., Ltd.
+8617531153977
allison@yan-xi.com China 5857 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
sales1@chuanghaibio.com China 5889 58

96-26-4(1,3-Dihydroxyaceton)Verwandte Suche:


  • Chromelin
  • NSC-24343
  • Oxantin
  • Oxatone
  • Protosol
  • Soleal
  • Triulose
  • Viticolor
  • 1,3-DIHYDROXYACETONE
  • 1,3-DIHYDROXY-2-PROPANE
  • 1,2-DIHYDROXY-2-PROPANONE
  • DIHYDROXYACETONE CRYSTALLINE
  • 1,3-Dihydroxyaceton
  • 1,3-DIHYDROXYACETONE (DHA)
  • Dihydroxyacetone ,98%
  • Dihydroxyacetone (250 mg)
  • 1,1-Dihydroxy-propan-2-one
  • 1,3-Dihydroxyacetone, 98%+
  • 1,3-Dihydroxyacetone Monomer
  • DIHYDROXYACETONE FOR SYNTHESIS
  • Nizatidine Impurity 3
  • Bis(hydroxymethyl)ketone
  • dihydroxyacetone (monomer)
  • 1,3-DIHYDROXYACETONE (DHA) Cas RN 96-26-4
  • 1,3-Dihydroxyacetone D4
  • PROPANE-1,3-DIOL-2-ONE
  • 1,3-dihydroxy-2-propanon
  • 1,3-Dihydroxydimethyl ketone
  • 1,3-Dihydroxypropanone
  • Aliphatic ketone
  • Dihyxal
  • Ketochromin
  • Otan
  • DIHYDROXYACETONE
  • 1,3-DIHYDROXYACTONE
  • 1,3-DIHYDROXY-2-PROPANONE
  • 2-Propanone, 1,3-dihydroxy-
  • 1,3-dihydroxypropan-2-one
  • Glycerone
  • 3-Dihydroxyacetone
  • 1,3 Dihydroxypropan-2-One(Dihydroxyacetone)
  • 4-Butylresorcino
  • DHA (Dihydroxyacetone)
  • Dihydroxyacetone, DHA
  • Hexane 110-54-3
  • Glycerol Impurity 15
  • 1,3-DihydroxyacetonChemicalbooke
  • 1,3-Dihydroxyacetone in Water
  • Dihydroxyacetone/1,3-Dihydroxyacetone
  • 96-26-4
  • Pharmaceutical intermediates
  • Imidazoles
  • 96-26-4
  • bc0001
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