Maprotilinhydrochlorid
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- CAS-Nr.
- 10347-81-6
- Bezeichnung:
- Maprotilinhydrochlorid
- Englisch Name:
- Maprotiline hydrochloride
- Synonyma:
- ba34276;Psymion;Maprolu;Deprilept;ciba34276ba;LUDIOMIL HCL;Ludiomil tab;Einecs 233-758-8;Ludiomil comprimes;ciba34276hydrochloride
- CBNumber:
- CB6297617
- Summenformel:
- C20H24ClN
- Molgewicht:
- 313.86
- MOL-Datei:
- 10347-81-6.mol
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Maprotilinhydrochlorid Eigenschaften
- Schmelzpunkt:
- 230-232°C
- Flammpunkt:
- 9℃
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: 50 mg/mL
- Aggregatzustand
- powder
- Farbe
- white
- Wasserl?slichkeit
- Soluble to 50mg/ml in water. Soluble in ethanol at 10mM
- Merck
- 14,5748
- InChI
- InChI=1/C20H23N.ClH/c1-21-14-6-12-20-13-11-15(16-7-2-4-9-18(16)20)17-8-3-5-10-19(17)20;/h2-5,7-10,15,21H,6,11-14H2,1H3;1H/t15-,20+;
- InChIKey
- NZDMFGKECODQRY-ZLYMRNBRNA-N
- SMILES
- [C@@]12(CCCNC)CC[C@@]([H])(C3C=CC=CC1=3)C1C=CC=CC2=1.Cl |&1:0,8,r|
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn,T,F |
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| R-S?tze: |
22-39/23/24/25-23/24/25-11 |
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| S-S?tze: |
7-16-36/37-45 |
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| RIDADR |
3249 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
KJ4555000 |
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| HazardClass |
6.1(b) |
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| PackingGroup |
III |
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| HS Code |
2921490002 |
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| Toxizit?t |
LD50 in mice, rats (mg/kg): ~750, ~900 orally (Hess) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
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Maprotilinhydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
Chemische Eigenschaften
Crystalline Solid
Verwenden
Maprotiline Hydrochloride has also been shown to block apoptosis of spiny neurons and inhibit SLC6A2.
Allgemeine Beschreibung
Maprotiline hydrochloride, N-methyl-9,10-ethanoanthracene-9(10H)-propanamine hydrochloride (Ludiomil), is sometimesdescribed as a tetracyclic rather than a tricyclic antidepressant.The description is chemically accurate, but the compound,nonetheless, conforms to the overall TCA pharmacophore. Itis a dibenzobicyclooctadiene and can be viewed as a TCAwith an ethylene-bridged central ring. The compound is notstrongly anticholinergic and has stimulant properties. It canhave effects on the cardiovascular system. It is a SNERI.
Biologische Aktivit?t
Selective noradrenalin re-uptake inhibitor.
Maprotilinhydrochlorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Maprotilinhydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 208)Lieferanten
10347-81-6(Maprotilinhydrochlorid)Verwandte Suche:
- 10-ethanoanthracene-9(10h)-propylamine,n-methyl-hydrochloride
- ba34276
- ciba34276ba
- ciba34276hydrochloride
- n-methyl-9,10-ethanoanthracene-9(10h)-propanaminehydrochloride
- 9-[GAMMA-METHYLAMINOPROPYL]-9,10-DIHYDRO-9,10-ETHANOANTHRACENE HYDROCHLORIDE
- 1-(3-METHYLAMINOPROPYL)DIBENZO[B,E]BICYCLO[2.2.2]OCTADIENE HYDROCHLORIDE
- MAPROTILENE HYDROCHLORIDE
- MAPROTILINE HYDROCHLORIDE
- LUDIOMIL HCL
- Deprilept
- N-Methyl-9,10-ethanoanthracene-9(10H)-propylamine Hydrochloride
- Psymion
- Ludiomil comprimes
- Ludiomil tab
- 9,10-Ethanoanthracene-9(10H)-propanamine, N-methyl-, hydrochloride
- 9-(γ-methylaminopropyl)-9,10-dihydro-9,10-ethanoanthracene hydrochloride
- Maprolu
- 9,10-Ethanoanthracene-9(10H)-propylamine, N-methyl-, hydrochloride
- Einecs 233-758-8
- Maprotiline hydrochloride,9-(γ-Methylaminopropyl)-9,10-dihydro-9,10-ethanoanthracene hydrochloride
- Maprotiline Hydrochloride (200 mg)
- Maprotiline, LudioMil Hydrochloride
- N-methyl-9,10-ethanoanthracene-9(10H)-propanamine,hydrochloride (1:1)
- Maprotiline hydrochloride solution
- Maprotiline hydrochloride CRS
- Maprotiline Hydrochloride, 98.0+ % (HPLC)
- MaprotilineHydrochloride>
- Maprotiline hydrochloride USP/EP/BP
- Maprotilinhydrochlorid
- 3-(9,10-Ethanoanthracen-9(10H)-yl)-N-methylpropan-1-amine hydrochloride
- Maprotiline hydrochloride 13CD3
- Maprotiline Hydrochloride (1375207)
- Maprotiline HCl|||Psymion|||Deprilept|||Ludiomil
- Maprotiline hydrochloride in methanol
- Maprotiline hydrochloride, Noradrenaline reuptake inhibitor
- Maprotiline hydrochloride, 10 mM in DMSO
- 10347-81-6
- C20H23NHCl
- Selective norepinephrine uptake inhibitor.
- Chemical Amines
- Amines
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Adrenoceptor
- Active Pharmaceutical Ingredients
