Indobufen
|
|
|
- CAS-Nr.
- 63610-08-2
- Englisch Name:
- Indobufen
- Synonyma:
- 2-(4-(1-oxoisoindolin-2-yl)phenyl)butanoic acid;d-INB;K 2930;K-3920;Ibustrin;INDOBUFEN;INDOBNFEN;lndobufen;d-Indobufen;Indobuprofen
- CBNumber:
- CB6213695
- Summenformel:
- C18H17NO3
- Molgewicht:
- 295.34
- MOL-Datei:
- 63610-08-2.mol
|
Indobufen Eigenschaften
- Schmelzpunkt:
- 182-184°
- Siedepunkt:
- 518.1±50.0 °C(Predicted)
- Dichte
- 1.275±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 4.39±0.10(Predicted)
- Farbe
- White
- InChI
- InChI=1S/C18H17NO3/c1-2-15(18(21)22)12-7-9-14(10-8-12)19-11-13-5-3-4-6-16(13)17(19)20/h3-10,15H,2,11H2,1H3,(H,21,22)
- InChIKey
- AYDXAULLCROVIT-UHFFFAOYSA-N
- SMILES
- O=C1C2C=CC=CC=2CN1C1C=CC(C(CC)C(=O)O)=CC=1
- CAS Datenbank
- 63610-08-2(CAS DataBase Reference)
- EPA chemische Informationen
- Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-.alpha.-ethyl- (63610-08-2)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
|
| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
|
Indobufen Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Indobufen is a platelet aggregation inhibitor related to the antiinflammatory agent
indoprofen. It has shown clinical efficacy in peripheral artery disease, in
prevention of deep vein thrombosis after myocardial infarction, and in blocking
excercise-induced increase in platelet aggregation in angina patients.
Verwenden
Indobufen is a platelet aggregation inhibitor. Indobufen is the anticoagulant drug and platelet aggregation inhibitor, which has anti-inflammatory analgesic effect. Indobufen is used as an antithrombotic.
Clinical Use
A reversible but very potent inhibitor of platelet COX-1 activity,
was shown to have comparable clinical efficacy to that of aspirin in prevention of DVT after
myocardial infarction and in blocking exercise-induced increase in platelet aggregation. In the
secondary prevention of thromboembolic events, 100 or 200 mg of indobufen twice daily is as
effective as warfarin or aspirin in patients with or without atrial fibrillation. Currently,
indobufen is only available for routine clinical use in Europe.
Indobufen Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Indobufen Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 229)Lieferanten
63610-08-2()Verwandte Suche:
- 1-Oxo-2-[p-[(α-ethyl)carboxyMethyl]phenyl]isoindoline
- 2-[p-(1-Oxo-2-isoindolinyl)phenyl]butyric Acid
- K 2930
- (+-)-butyricaci
- 1-oxo-2-(p-((alpha-ethyl)carboxymethyl)phenyl)isoindoline
- 4-(1,3-dihydro-1-oxo-2h-isoindol-2-yl)-alpha-ethyl-benzeneaceticacid
- 2-[4-(1-OXO-1,3-DIHYDRO-ISOINDOL-2-YL)-PHENYL]-BUTYRIC ACID
- lndobufen
- INDOBNFEN
- INDOBUFEN
- 2-[4-(1-oxo-2-isoindolinyl)phenyl]butyric acid
- (2R)-2-[4-(3-Oxo-1H-isoindol-2-yl)phenyl]butanoic acid
- 1-Oxo-2-(p-((a-ethyl)carboxymethyl)phenyl)isoindoline
- 4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)a-ethyl-benzeneacetic acid
- Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-a-ethyl-
- Butyric acid, 2-(p-(1-oxo-2-isoindolinyl)phenyl)-, (+-)
- (±)-4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-α-ethylbenzeneacetic acid
- (αR)-4-[(1,3-Dihydro-1-oxo-2H-isoindole)-2-yl]-α-ethylbenzeneacetic acid
- [R,(-)]-4-[(1,3-Dihydro-1-oxo-2H-isoindole)-2-yl]-α-ethylbenzeneacetic acid
- (αS)-4-[(1,3-Dihydro-1-oxo-2H-isoindol)-2-yl]-α-ethylbenzeneacetic acid
- d-INB
- d-Indobufen
- Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-alpha-ethyl-
- Ibustrin
- K-3920
- Ibustrin， K 3920
- Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-α-ethyl-
- Indobufen USP/EP/BP
- 63610-08-2,Indobufen
- (2S)-2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanoic acid
- 2-(4-(1-oxoisoindolin-2-yl)phenyl)butanoic acid
- Indole cloth Finn
- Indobufen WRS
- 2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanoicaci
- Indobuprofen
- 63610-08-2
- Amines
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- 63610-08-2
- API
