Ethylenbis[chlordimethylsilan] Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R34:Verursacht Ver?tzungen.
R10:Entzündlich.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S28:Bei Berührung mit der Haut sofort abwaschen mit viel . . . (vom Hersteller anzugeben).
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S16:Von Zündquellen fernhalten - Nicht rauchen.

Chemische Eigenschaften

transparent low melting solid

Physikalische Eigenschaften

mp 36–41°C; bp 198°C/734 mmHg.

Verwenden

1,2-Bis(chlorodimethylsilyl)ethane can be used as a reagent for the protection of primary amines as their tetramethyldisilylazacyclopentane or Stabase adducts; used in combination with zinc to form organozinc carbenoids; electrophilic silylating reagent.
Protection of Primary Amines.
Few protecting groups exist for the N,N-diprotection of primary amines. The tetramethyldisilylazacyclopentane or Stabase adduct (3) is particularly attractive for this purpose due to its ease of preparation, base stability and facile removal. This cyclic disilane is easily prepared (eq 1) from the commercially available title reagent (1).For primary amines with pKa values between 10 and 11, typical reaction conditions involve the treatment of a dichloromethane solution of the amine with (1) in the presence of two equivalents of triethylamine at room temperature. Subsequent workup with aqueous dihydrogen phosphate provides (3) in excellent yields.1 Stabase adducts are quite stable to strongly basic conditions such as n-butyllithium and s-butyllithium (at ?25°C), lithium diisopropylamide, and Grignard reagents making it a superb candidate for use in the alkylation of substrates bearing a primary amine. For example, protected amino acid derivatives are easily alkylated (eq 2).After formation of the lithium enolate of the protected ethyl glycinate (4) under standard conditions, exposure to various alkyl halides or aldehydes yields alkylation products such as (5).

Ethylenbis[chlordimethylsilan] Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Ethylenbis[chlordimethylsilan] Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	18751	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60
Zjartschem	+86-571 87238903	jocelynpan@zjarts.com	CHINA	988	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29880	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
Hubei Co-Formula Material Tech Co., Ltd.	+86-27-84459282	sales@cfmats.com	CHINA	882	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	11817	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58

13528-93-3(Ethylenbis[chlordimethylsilan])Verwandte Suche:

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• 1,2-ethanediylbis[chlorodimethyl-silan
• 1,2-Bis(chlorodimethylsilyl)ethane,96%
• [-CH2Si(CH3)2Cl]2
• 1,2-Bis(dimethylchlorosily)ethane
• Tetra-Methyl-Di-Chloro-Ethyl-Di-SilaneOR1,2-Bis(chlorodimethylsilyl)ethane
• [Protecting Reagent for PriMary AMines]
• 1,2-Bis(chlorodiMethylsilyl)ethane 
• 1,2-Bis(chlorodiMethylsilyl)ethane, 96% 25GR
• 1,2-Bis(chlorodiMethylsilyl)ethane, 96% 5GR
• 1,2-Bis(chlorodiMethylsilyl)ethane 96%
• 1,2-Bis(chlorodimethylsilyl)ethane(1,1,4,4-Tetramethyl-1,4-dichlorodisilethylene)
• 1,1,4,4-Tetramethyl-1,4-dichloro-disilethylene, 2,5-Dichloro-2,5-dimethyl-2,5-disilahexane
• 1,2-ethanediylbis[chlorodimethyl-Silane
• SILANE BM2E
• STABASE
• 1,2-BIS(CHLORODIMETHYLSILYL)ETHANE
• 1,2-BIS(DIMETHYLCHLOROSILYL)ETHANE
• 1,1,4,4-TETRAMETHYL-1,4-DICHLORODISILETHYLENE
• 1,1,4,4-TETRAMETHYL-1,4-DICHLORO-DISYLETHYLENE
• 2,5-DICHLORO-2,5-DIMETHYL-2,5-DISILAHEXANE
• ethylenebis[chlorodimethylsilane]
• 1,2-Bis(chlorodimethylsilyl)ethane [Protecting Reagent for Primary Amines]
• 1,2-Bis(chlorodimethylsily)ethane
• 1,2-Bis(chlorodimethylsilyl)ethane [Protecting Reagent for Primary Amines]>
• Silane, 1,1'-(1,2-ethanediyl)bis[1-chloro-1,1-dimethyl-
• 1,2-Bis(chlorodimethylsilyl)
• chloro[2-(chlorodimethylsilyl)ethyl]dimethylsilane
• 1,1,4,4-TETRAMETHYL-1,4-DICHLORODISILYLETHYLENE
• Patchouli oil 8014-09-3
• 1,1'-(1,2-Ethanediyl)bis[1-chloro-1,1-dimethylsilane
• DK065
• DK525
• 1,1'-(1,2-Ethanediyl)bis[1-chloro-1,1-dimethylsilane
• 13528-93-3
• -CH2SiCH32Cl2
• C6H16Cl2Si2
• Protection and Derivatization
• Protecting and Derivatizing Reagents
• Silicon-Based
• Synthetic Reagents
• Monochlorosilanes
• Si-Cl Compounds
• Si (Classes of Silicon Compounds)
• Protection & Derivatization Reagents (for Synthesis)
• Silicon Compounds (for Synthesis)
• Monochlorosilanes
• Protection & Derivatization Reagents (for Synthesis)
• Si (Classes of Silicon Compounds)
• Si-Cl Compounds
• Silicon Compounds (for Synthesis)
• Synthetic Organic Chemistry