N-Nitroso-N-phenylhydroxylamin,Ammoniumsalz Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R25:Giftig beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R40:Verdacht auf krebserzeugende Wirkung.
R45:Kann Krebs erzeugen.
R43:Sensibilisierung durch Hautkontakt m?glich.
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
Aussehen Eigenschaften
C6H9N3O2; N-Nitroso-N-phenylhydroxyamin Ammoniumsalz, N-Phenyl-N-nitrosohydroxylamin Ammoniumsalz. Gelber Feststoff mit schwachem Eigengeruch.
Gefahren für Mensch und Umwelt
Gesundheitsschädlich beim Verschlucken.
LD
50 (oral, Ratte): 199 mg/kg
Schutzma?nahmen und Verhaltensregeln
Schutzhandschuhe als kurzzeitiger Staubschutz.
Verhalten im Gefahrfall
Einatmen von Stäuben vermeiden.
Vorsichtig trocken aufnehmen. Der Entsorgung zuführen. Nachreinigen.
Wasser.
Brennbar. Im Brandfall können nitrose Gase entstehen.
Erste Hilfe
Nach Hautkontakt: Mit reichlich Wasser abwaschen.
Nach Augenkontakt: Bei geöffnetem Lidspalt mit reichlich fliessendem Wasser (Augendusche!) mindestens 15 Minuten ausspülen. Sofort Augenarzt hinzuziehen.
Nach Einatmen: Frischluft. Arzt hinzuziehen.
Nach Verschlucken: Reichlich Wasser trinken. Erbrechen auslösen. Sofort Arzt hinzuziehen.
Nach Kleidungskontakt: Kontaminierte Kleidung entfernen.
Ersthelfer: siehe gesonderten Anschlag
Sachgerechte Entsorgung
Gelöst in z.B. Ethanol als halogenfreie, organische Lösemittelabfälle.
Chemische Eigenschaften
Cupferron is a creamy-white crystalline compound
Verwenden
The reagent used to be considered as specific for iron(II) and copper(II). However,
in the course of later analytical studies it turned out that cupferron forms
complexes with several other metals too, even in acidic medium. It is used today
primarily for the determination of copper(II), but it has proved suitable for the
determination of aluminium(III), bismuth(III), iron(III), mercury(II), thorium(IV),
tin(IV), titanium(III), vanadium(IV) and zirconium(IV) as well. Of these, the
zirconium(IV) complex is the most stable. Cupferron precipitates zirconium(IV)
quantitatively from aqueous media containing sulfuric acid.
The reagent gives a precipitate with most of the above metal ions even in strong
mineral acidic medium. Only the aluminium(III) complex does not precipitate in
the presence of mineral acids.
By means of cupferron many metal ions can be separated: thus, for instance,
iron(III) can be separated from aluminium(III) and manganese(II) and titanium
(IV), zirconium(IV) and hafnium(IV) from many other metal ions, etc. Though
the reagent makes possible several separations, the precipitates are not exactly of
stoichiometric composition (they almost always contain some excess of the ligand).
Hence instead of being directly weighed, the precipitates are usually ignited and
the metal oxide residues weighed.
Allgemeine Beschreibung
Light yellow or cream-colored crystals or a brown crystalline solid. As a reagent in the separation of copper and iron.
Air & Water Reaktionen
Hygroscopic. Soluble in water.
Reaktivit?t anzeigen
Cupferron may be sensitive to prolonged exposure to air. Incompatible with strong oxidizing agents, strong acids and strong bases. Forms unstable solutions with thorium, titanium and zirconium salts.
Brandgefahr
Flash point data for Cupferron are not available; however, Cupferron is probably combustible.
Sicherheitsprofil
Confirmed carcinogen
with experimental carcinogenic and
tumorigenic data. Poison by intravenous
route. An eye irritant. Solutions with
thorium salts are unstable explosives above
15°C. Solutions with titanium or zirconium
salts are unstable explosives above 40℃.
When heated to decomposition it emits very
toxic NH3 and NOx. See also N-NITROSO
COMPOUNDS and AMINES
m?gliche Exposition
Cupferron is used to separate tin from zinc, and copper and iron from other metals in the laboratory. Cupferron also finds application as a quantitative reagent for vanadates and titanium; and for the colorimetric determination of aluminum. The potential for exposure appears to be greatest for those engaged in analytical or research studies involving use of the chemical. Workers may also be exposed to the compound during manufacturing processes.
Carcinogenicity
Cupferron is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Versand/Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
l?uterung methode
Recrystallise it twice from EtOH after treatment with Norite and finally once with EtOH. The crystals are washed with diethyl ether and air dried, then stored in the dark over solid ammonium carbonate. A standard solution (ca 0.05M prepared in air-free H2O) is prepared daily from this material for analytical work and is essentially 100% pure. [Olsen & Elving Anal Chem 26 1747 1954.] It can also be washed with Et2O, dried and stored as stated. In a sealed, dark container it can be stored for at least 12 months without deterioration. 260nm (CHCl3). max [Marvel Org Synth Coll Vol I 177 1941, Elving & Olson J Am Chem Soc 78 4206 1956, Beilstein 16 IV 891.] Possible CARCINOGEN.
Inkompatibilit?ten
Forms unstable and possibly explosive compounds with thorium salts; titanium, zirconium.
N-Nitroso-N-phenylhydroxylamin,Ammoniumsalz Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
