3,5-Diiod-L-tyrosin
|
|
|
- CAS-Nr.
- 300-39-0
- Bezeichnung:
- 3,5-Diiod-L-tyrosin
- Englisch Name:
- 3,5-Diiodo-L-tyrosine dihydrate
- Synonyma:
- (S)-2-AMino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid;diiodotyrosine;L-3,5-DiioDOTyrosine;Liothyronine sodium EP Impurity B;AGONTAN;DITYRIN;3,5-Diiodo-L;L-Diiodotyrosine;H-TYR(3,5-I2)-OH;IODOGORGOIC ACID
- CBNumber:
- CB5490149
- Summenformel:
- C9H9I2NO3
- Molgewicht:
- 432.98
- MOL-Datei:
- 300-39-0.mol
|
3,5-Diiod-L-tyrosin Eigenschaften
- Schmelzpunkt:
- 200 °C (dec.)(lit.)
- alpha
- -20.7 º (c=2.5, 0.1N NaOH/H2O)
- Siedepunkt:
- 546.5°C (rough estimate)
- Dichte
- 2.405±0.06 g/cm3(Predicted)
- Brechungsindex
- 1.2 ° (C=5, 1mol/L HCl)
- storage temp.
- 2-8°C
- L?slichkeit
- Aqueous Acid (Slightly), DMSO (Slightly)
- pka
- 2.12(at 25℃)
- Aggregatzustand
- crystalline
- Farbe
- white
- Wasserl?slichkeit
- slightly soluble
- Sensitive
- Light Sensitive
- CAS Datenbank
- 300-39-0(CAS DataBase Reference)
- NIST chemische Informationen
- 3,5-Diiodo-l-tyrosine(300-39-0)
- EPA chemische Informationen
- L-Tyrosine, 3,5-diiodo- (300-39-0)
3,5-Diiod-L-tyrosin Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Beschreibung
Diiodotyrosine does not possess pronounced hormonal activity. However, it stops production
of thyrotropic hormone by the anterior lobe of the hypophysis, which activates thyroid
gland activity.
Chemische Eigenschaften
white to beige powder
Verwenden
It is used for hyperthyroid forms of endemic and sporadic goiters, diffuse, toxic goiters,
and other illnesses accompanied by thyrotoxicity.
Definition
ChEBI: A diiodotyrosine that is L-tyrosine carrying iodo-substituents at positions C-3 and C-5 of the benzyl group. It is an intermediate in the thyroid hormone synthesis.
l?uterung methode
It forms crystals from H2O [solubility (g/L): 0.204 at 0o, 1.86 at 50o, 5.6 at 75o and 17.0 at 100o]. Also recrystallise it from 50% or 70% EtOH. When boiled in EtOH the crystals swell, and on further boiling a gelatinous precipitate is formed [Harrington Biochem J 22 1434 1928, Jurd J Am Chem Soc 77 5747 1955]. It also crystallises from cold dilute ammonia on adding acetic acid to pH 6. [Beilstein 14 IV 2370.]
3,5-Diiod-L-tyrosin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3,5-Diiod-L-tyrosin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 312)Lieferanten
300-39-0(3,5-Diiod-L-tyrosin)Verwandte Suche:
12-DEOXYPHORBOL 13-ACETATE
H-ARG-ARG-LEU-ILE-GLU-ASP-ASN-GLU-TYR-THR-ALA-ARG-GLY-OH
L-Alanin
Tyrosin
Boc-D-Tyrosine
2-Piperidon
4-(4-Hydroxy-3,5-diiodphenoxy)-3,5-diiodphenylessigsure
Liothyronin
Liothyroninnatrium
Levothyroxinnatrium
N-Acetyl-3,5-diiod-L-tyrosin
DL-Thyroxin
3,5-Diiodthyronin
5,5'-Diisopropyl-2,2'-dimethylbiphenyl-4,4'-diyldihypoiodit
3,6-Dimethylpiperazin-2,5-dion
D-4-(4-Hydroxy-3,5-diiodphenoxy)-3,5-diiodbenzylalanin
N-(N-Acetyl-3-phenyl-L-alanyl)-3,5-diiodo-L-tyrosin
FOROXYMITHINE
- 3,5-Diiodo-4-hydroxy-β-phenylalanine
- 3,5-diiodo-l-tyrosin
- 3,5-Diiodotyrocine
- 3,5-Iodo-L-tyrosine
- 3,5-L-Diiodotyrosine
- 4-Hydroxy-3,5-diiodophenylalanine
- Tryosine, 3,5-diiodo-
- Tyrosine, 3,5-diiodo-, L-
- L-Diiodotyrosine
- 3,5-Diiodo-L-tyrosine dihydrate,99%
- 5-Diiodo-L-tyrosinedehydrate
- L-4-hydroxy-3,5-diiodo-phenylalanine
- DI-IODO-L-TYROSINE(P)
- 3,5-Diiodo-L-Tyr-OH
- 3,7-DibroMo-L-Tyrosine
- (2S)-2-amino-3-(4-hydroxy-3,5-diiodo-phenyl)propanoic acid
- H-Tyr(3,5-Di-I)-OH
- 3,5-Diiodo-L-tyrosinedehydrate
- 3,5-DIIODO-4-HYDROXY-BETA-PHENYLALANINE
- 3,5-DIIODINE-L-TYROSINE
- 3,5-DIIODO-BETA(4-HYDROXYPHENYL)ALANINE
- 3,5-DIIODO-TYROSINE
- 4-HYDROXY-3,5-DIIODOPHENYLALANINE, 2-AMINO-3-(4-HYDROXY-3,5-DIIODOPHENYL)PROPIONIC ACID
- AGONTAN
- L-TYROSINE, 3,5-DIIODO-
- DITYRIN
- H-TYR(3,5-I2)-OH
- IODOGORGOIC ACID
- H-3,5-DIIODO-TYR-OH
- H-L-TYR(3,5-I2)-OH
- 3,5-Diiodo-beta-(p-hydroxyphenyl)alanine dihydrate
- H-L-Tyr(3,5-I2)-OH*2H2O
- Liothyronine EP Impurity B
- 3,5-Diiodo-L-Tyr-OH, 98.5%
- -tyrosine dihydrate
- 3,5-Diiodo-L
- Levofolinate Impurity 2 (Liothyronine EP Impurity B)
- 3,5-Diiodo-L-tyrosine dihydrate USP/EP/BP
- 3,5-Diiodo-L-tyrosine dihydrate, BR
- TIANFU CHEM--3,5-Diiodo-L-tyrosine dihydrate
- diiodotyrosine
- L-3,5-DiioDOTyrosine
- (S)-2-AMino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid
- Liothyronine sodium EP Impurity B
- Liothyronine Impurity 2 (Liothyronine EP Impurity B)
- DIIODO-L-TYROSINE
- 3,5-Diiodo-L-tyrosine (Liothyronine Impurity)
- 3,5-Diiodo-L-tyrosine dihydrate, 10 mM in DMSO
- 300-39-0
- C9H9I2NO3x2H2O
- C9H9I2NO3
- C9H912NO3
- C9H9I2NO32H2O
- Biochemicals and Reagents
- Amino Acids and Peptides
- BioChemical
- Modified Amino Acids
- A - H
