5-Amino-1H-imidazol-4-carboxamidmonohydrochlorid
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- CAS-Nr.
- 72-40-2
- Bezeichnung:
- 5-Amino-1H-imidazol-4-carboxamidmonohydrochlorid
- Englisch Name:
- 4-Amino-5-imidazolecarboxamide hydrochloride
- Synonyma:
- AICA;AICA HCL;AIC .cntdot. HCl;AICA HYDROCHLORIDE;TIMTEC-BB SBB003938;5-Amino-1H-imidazoL;LABOTEST-BB LT00440910;e-4-carboxamide hydrochL;Temozolomide intermediate;Dacarbazine EP Impurity B
- CBNumber:
- CB5300628
- Summenformel:
- C4H7ClN4O
- Molgewicht:
- 162.58
- MOL-Datei:
- 72-40-2.mol
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5-Amino-1H-imidazol-4-carboxamidmonohydrochlorid Eigenschaften
- Schmelzpunkt:
- 250-252 °C (dec.)(lit.)
- storage temp.
- 2-8°C
- L?slichkeit
- water: soluble50mg/mL, clear, light yellow
- Aggregatzustand
- Crystals or Crystalline Powder
- Farbe
- White
- Wasserl?slichkeit
- SOLUBLE
- Sensitive
- Hygroscopic
- BRN
- 3701645
- Stabilit?t:
- Hygroscopic
- InChI
- InChI=1S/C4H6N4O.ClH/c5-3-2(4(6)9)7-1-8-3;/h1H,5H2,(H2,6,9)(H,7,8);1H
- InChIKey
- MXCUYSMIELHIQL-UHFFFAOYSA-N
- SMILES
- C1(N=CNC=1N)C(=O)N.Cl
- CAS Datenbank
- 72-40-2(CAS DataBase Reference)
- NIST chemische Informationen
- Imidazole-4(5)-carboxamide, 5-(4)-amino-, hydrochloride(72-40-2)
- EPA chemische Informationen
- 1H-Imidazole-4-carboxamide, 5-amino-, monohydrochloride (72-40-2)
5-Amino-1H-imidazol-4-carboxamidmonohydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
very slightly beige fine powder
Verwenden
5-Amino-4-imidazolecarboxamide hydrochloride was used in the synthesis of heterocyclic compounds such as guanine, purines and pyrimidines.
Allgemeine Beschreibung
Corrosion inhibition and adsorption characteristics of 5-amino-4-imidazolecarboxamide hydrochloride on aluminum in 1M HCl has been investigated.
Synthese
47 g of sodium nitrite was dissolved in 1.2 liters of water; The solution was cooled to 0° C. 100 g of 5-aminoimidazole-4 carboxamide was dissolved in a solution of hydrochloric acid (80 ml of 36% HCL in 720 ml water) with stirring. The resultant 5-aminoimidazole-4 carboxamide hydrochloride solution was added slowly, drop-wise, over 20-30 minutes at 0-5° C. After the addition was completed, the reaction mixture was stirred for 10 minutes and filtered. The solid obtained was suspended in 400 ml DM water and stirred for 15 minutes. The suspension was filtered and suction-dried for 15 minutes. The obtained solid was suspended in 500 ml of THF and stirred for 15 minutes. The suspension was filtered and suction-dried for 15 minutes. Finally, the solid was dried at 45° C. to afford 4-Amino-5-imidazolecarboxamide hydrochloride.
l?uterung methode
Recrystallise the hydrochloride from EtOH. [Kuroda & Hakko JEst(1) Est(2)Heterocycl Chem 30 593 1993, Alhede et al. J Org Chem 56 2139 1991, Cheru et al. Heterocycles 24 1133 1992, Beilstein 25 II 221, 25 III/IV 4329.]
5-Amino-1H-imidazol-4-carboxamidmonohydrochlorid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5-Amino-1H-imidazol-4-carboxamidmonohydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 441)Lieferanten
72-40-2(5-Amino-1H-imidazol-4-carboxamidmonohydrochlorid)Verwandte Suche:
- 5-aminoimidazole-4-carboxamide HCl
- 5-amino-1H-imidazole-4-carboxamide monohydrochloride
- 4-Amino-5-imidazolecarboxamide hydrochloride;AICA
- 5-Amino-1H-imidazole-4-carboxamide hydrochloride
- 5-Aminoindazole-4-Carboxyamide Hydrochloride
- 5-Amino-4-imidazolecarboxamide hydrochloride, 98
- 4(5)-Amino-5(4)-Imidazolecarboxamide HCl
- LABOTEST-BB LT00440910
- Temozolomide intermediate
- 5-amino-1h-imidazole-4-carboxamidmonohydrochloride
- 5-Aminoimidazol-4-carboxamide, hydrochloride
- 5-Imidazolecarboxamide, 4-amino-, hydrochloride
- AIC .cntdot. HCl
- 1H-Imidazole-4-carboxamide, 5-amino-, monohydrochloride
- 4-Amino-5-carboxamido imidazole hydrochloride
- 4-amino-5-imidazolecarboxamidhydrochloride
- 4-Aminoimidazole-5-carboxamide hydrochoride
- 5-amino-4-imidazolecarboxamide hydrochloride (intermediate of dacarbazine)
- 5-Amino-1H-imidazole-4-carboxamide hydrochloride 98%
- 5-amino-1H-imidazole-4-carboxamide HCl
- 4-Amino-5-(aminocarbonyl)imidazole Hydrochloride
- 4-AMINO-5-IMIDAZOLECARBOXAMIDE HCL, (AICA) 98+%
- 4-AMINO-5-IMIDAZOLECARBOXAMIDE HYDROCHLORIDE 99%
- 4-Amino-5-imidazolecarboxamide hydrochloride ,99%
- 4-Amino-5-imidazolecarboxamide hydrochloride,98%
- Dacarbazine Related Compound A (50 mg) (5-aminoimidazole-4-carboxamide hydrochloride)
- 4-amino-1H-imidazole-5-carboxamide HCL
- Dacarbazine Related CoMpound A
- 5-AMino-3H-iMidazole-4-carboxylic acid aMide hydrochloride
- 5-AMONO-4-IMIDAZOLE CARBOXAMIDE HYDROCHLORIDE
- AMino - 4-5 - iMidazole carboxaMide hydrochloride
- 5(4)-AMINO-4(5)-(AMINOCARBONYL)IMIDAZOLE HYDROCHLORIDE
- 5(4)-AMINO-4(5)-IMIDAZOLECARBOXAMIDE HYDROCHLORIDE
- 5(4)-AMINOIMIDAZOLE-4(5)-CARBOXAMIDE HYDROCHLORIDE
- 5-AMINO-4-IMIDAZOLECARBOXAMIDE HYDROCHLORIDE
- 5-AMINOIMIDAZOLE-4-CARBOXAMIDE HYDROCHLORIDE
- 5-AMINO-3H-IMIDAZOLE-4-CARBOXYLIC ACID AMIDE HCL
- 4-AMINO-1H-IMIDAZOLE-5-CARBOXAMIDE HYDROCHLORIDE
- 4-AMINO-5-IMIDAZOLECARBOXAMIDE HCL
- 4-AMINO-5-IMIDAZOLECARBOXAMIDE HYDROCHLORIDE
- 4-AMINO-5-CARBOXAMIDO IMIDAZOLE HCL
- 4(5)-AMINO-5(4)-IMIDAZOLECARBOXAMIDE HYDROCHLORIDE
- 4-AMINOIMIDAZOLE-5-CARBOXAMIDE HYDROCHLORIDE
- 4-Aminoimidazole-5-carboxamidehydrochloride,98%
- 5-Amino-4-imidazolecarboxamide hydrochloride 98%
- Imidazole-4-carboxamide, 5-amino-, monohydrochloride
- AICA
- AICA HCL
- AICA HYDROCHLORIDE
- TIMTEC-BB SBB003938
- 4-Amino-5-carbamoylimidazole salt of hydrochloric acid
- Dacarbazine EP Impurity B(USP RC A)
- imidazolecarboxamide hydrochloride
- 5(4)-Amino-4(5)-(aminocarbonyl)imidazole Hydrochloride >
- Dacarbazine EP Impurity B
- 5-Amino-1H-imidazoL
- e-4-carboxamide hydrochL
- Dacarbazine EP Impurity B HCl
