GSK-3β Inhibitor XVIII Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

GSK3β inhibitor XVIII is an inhibitor of glycogen synthase kinase 3β (GSK3β; IC₅₀ = 64 nM). It induces expression of a luciferase reporter in HEK293 cells expressing wild-type Wnt (EC₅₀ = ~1.25 μM) but not in cells expressing a β-catenin/TCF binding site-mutant Wnt. GSK3β inhibitor XVIII increases β-catenin accumulation in the nucleus of HEK293 cells. It induces proliferation of R7T1 β-cells (EC₅₀ = 1,143 nM), an effect that can be blocked by the COX and Wnt signaling inhibitor sulindac , and rat primary β-cells.

GSK-3β Inhibitor XVIII Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

GSK-3β Inhibitor XVIII Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
BOC Sciences	16314854226	info@bocsci.com	United States	9923	65
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11217	58
Jinan Jiuli Biotechnology Co. , Ltd.	15865264761	486064515@qq.com	China	3642	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24647	58
Nanjing Tengyi Biotechnology Co., Ltd	025-58851786 17714337195	sales@tybiochem.com	China	6813	58
Nantong Hanfang Biotechnology Co. , Ltd.	18616537568	hanfangpharma@126.com	China	30961	58
	4008-099-669	23419001name@qq.com	CHINA	68144	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	cindy.huang@synzest.com	China	12005	58

1139875-74-3()Verwandte Suche:

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