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  • 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carbonsure

    Trolox  Struktur
    53188-07-1
    CAS-Nr.
    53188-07-1
    Bezeichnung:
    6-Hydroxy-2,5,7,8-tetramethylchroman-2-carbonsure
    Englisch Name:
    Trolox
    Synonyma:
    TROLOX;troloxc;TROLOX(R);trolox tm;TROLOXTM C;Trolox(R),97%;Trolox, 97% 1GR;Trolox, 97% 5GR;Trolox Standard;TIMTEC-BB SBB005933
    CBNumber:
    CB7188583
    Summenformel:
    C14H18O4
    Molgewicht:
    250.29
    MOL-Datei:
    53188-07-1.mol

    6-Hydroxy-2,5,7,8-tetramethylchroman-2-carbonsure Eigenschaften

    Schmelzpunkt:
    187-189 °C (lit.)
    Siedepunkt:
    313.42°C (rough estimate)
    Dichte
    1.0616 (rough estimate)
    Brechungsindex
    1.4970 (estimate)
    storage temp. 
    2-8°C
    L?slichkeit
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml). Also soluble in Water at alkalinepH.
    Aggregatzustand
    Crystalline Powder
    pka
    3.35±0.20(Predicted)
    Farbe
    White to faintly beige
    Wasserl?slichkeit
    water: 0.5mg/mL (slightly soluble)
    ethanol: 150mg/mL
    methanol: soluble
    BRN 
    1384051
    Stabilit?t:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    InChI
    InChI=1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)
    InChIKey
    GLEVLJDDWXEYCO-UHFFFAOYSA-N
    SMILES
    C1(C)(C(O)=O)OC2=C(C)C(C)=C(O)C(C)=C2CC1
    CAS Datenbank
    53188-07-1(CAS DataBase Reference)
    EPA chemische Informationen
    3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid (53188-07-1)
    Sicherheit
    • Risiko- und Sicherheitserkl?rung
    • Gefahreninformationscode (GHS)
    Kennzeichnung gef?hrlicher Xi
    R-S?tze: 36/37/38
    S-S?tze: 26-36
    WGK Germany  2
    RTECS-Nr. DJ2273000
    HS Code  29339900
    Bildanzeige (GHS) GHS hazard pictograms
    Alarmwort Warnung
    Gefahrenhinweise
    Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
    H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
    H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
    H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
    Sicherheit
    P261 Einatmen von Staub vermeiden.
    P264 Nach Gebrauch gründlich waschen.
    P264 Nach Gebrauch gründlich waschen.
    P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
    P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

    6-Hydroxy-2,5,7,8-tetramethylchroman-2-carbonsure Chemische Eigenschaften,Einsatz,Produktion Methoden

    R-S?tze Betriebsanweisung:

    R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

    S-S?tze Betriebsanweisung:

    S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
    S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

    Chemische Eigenschaften

    white to fainly beige crystalline powder

    Definition

    ChEBI: A chromanol that is 6-hydroxychromane which is substituted by a carboxy group at position 2 and by methyl groups at positions 2, 5, 7, and 8. A cell-permeable, water-soluble analogue of vitamin E, it is used as a standard for measuring the antioxidant capa ity of complex mixtures.

    Allgemeine Beschreibung

    (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (Trolox) exhibits radical scavenging and antioxidant activities.

    Mechanism of action

    Trolox can protect against oxidative stress, genotoxicity and inflammation induced by CS through ROS scavenging mechanism, and serve as a potential antioxidant prevention strategy against oxidative injury of ATII cells in CS-related lung diseases.

    6-Hydroxy-2,5,7,8-tetramethylchroman-2-carbonsure Upstream-Materialien And Downstream Produkte

    Upstream-Materialien

    Downstream Produkte


    6-Hydroxy-2,5,7,8-tetramethylchroman-2-carbonsure Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

    Global( 292)Lieferanten
    Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
    TCI AMERICA
    800-4238616
    sales@tciamerica.com Americas 23653 75
    Hebei Mujin Biotechnology Co.,Ltd
    +86 13288715578 +8613288715578
    sales@hbmojin.com China 12825 58
    Hebei Weibang Biotechnology Co., Ltd
    +8617732866630
    bess@weibangbio.com China 18147 58
    Henan Tianfu Chemical Co.,Ltd.
    +86-0371-55170693 +86-19937530512
    info@tianfuchem.com China 21632 55
    Nanjing ChemLin Chemical Industry Co., Ltd.
    025-83697070
    product@chemlin.com.cn CHINA 3009 60
    Hubei Jusheng Technology Co.,Ltd.
    18871490254
    linda@hubeijusheng.com CHINA 28172 58
    Hebei Yanxi Chemical Co., Ltd.
    +8617531153977
    allison@yan-xi.com China 5855 58
    TargetMol Chemicals Inc.
    +1-781-999-5354 +1-00000000000
    marketing@targetmol.com United States 32161 58
    Career Henan Chemica Co
    +86-0371-86658258 +8613203830695
    laboratory@coreychem.com China 30233 58
    Hefei TNJ Chemical Industry Co.,Ltd.
    +86-0551-65418671 +8618949823763
    sales@tnjchem.com China 34563 58

    53188-07-1(6-Hydroxy-2,5,7,8-tetramethylchroman-2-carbonsure)Verwandte Suche:


    • 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2h-1-benzopyran-2-carboxylicaci
    • troloxc
    • 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID
    • (+/-)-6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMANE-2-CARBOXYLIC ACID
    • TROLOX(R)
    • TROLOXTM C
    • TIMTEC-BB SBB005933
    • trolox tm
    • (+/-)-6-HYDROXY-2,5,7,8-TETRAMETHYL-CHRO M.-2-CARBOXYL.AC
    • rac-2,5,7,8-Tetramethyl-6-hydroxychroman-2α*-carboxylic acid
    • 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid
    • Trolox(R),97%
    • Trolox, 97% 1GR
    • Trolox, 97% 5GR
    • 6-hydroxy-2,5,7,8-tetraMethychroMan-2-caboxylic acid (Trolox)
    • (+/-)-6-Hydroxy-2,5,7,8-tetraMethylchroMane-2-carboxylic acid 97%
    • 53188-07-1 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID
    • 6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromene-2-carboxylic acid
    • 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylicAcid>
    • Trolox Standard
    • 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-
    • 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID ISO 9001:2015 REACH
    • TROLOX
    • Ferroptosis,Inhibitor,Apoptosis,Reactive Oxygen Species,inhibit,Trolox
    • Trolox, Antioxidant vitamin E derivative
    • 53188-07-1
    • 3188-07-1
    • Heterocyclic Building Blocks
    • Building Blocks
    • Benzopyrans
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