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alpha-Arbutin

alpha-Arbutin Struktur
84380-01-8
CAS-Nr.
84380-01-8
Englisch Name:
alpha-Arbutin
Synonyma:
Alpha Arbutin Powder;Α-ARBUTIN;α-Arbutin;a-Arbutin;4-hydroquinone-alpha-d-glucopyranoside;(2R,3S,4S,5R,6S)-2-(HYDROXYMETHYL)-6-(4-HYDROXYPHENOXY)TETRAHYDROPYRAN-3,4,5-TRIOL;(2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydro-2H-pyran-3,4,5-triol;LGB-AA;Alpha bear;alpha-arbutin
CBNumber:
CB3855311
Summenformel:
C12H16O7
Molgewicht:
272.25
MOL-Datei:
84380-01-8.mol

alpha-Arbutin Eigenschaften

Schmelzpunkt:
195-196°C
Siedepunkt:
561.6±50.0 °C(Predicted)
Dichte
1.556±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
10.10±0.15(Predicted)
Farbe
White to Off-White
BRN 
89675
InChI
InChI=1/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12+/s3
InChIKey
BJRNKVDFDLYUGJ-ZIQFBCGOSA-N
SMILES
O(C1C=CC(O)=CC=1)[C@@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O |&1:8,9,10,12,14,r|
CAS Datenbank
84380-01-8(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
WGK Germany  3
HS Code  2938.90.0000
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P271 Nur im Freien oder in gut belüfteten R?umen verwenden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P302+P352 BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.
P304+P340 BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.
P330 Mund ausspülen.
P332+P313 Bei Hautreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
P337+P313 Bei anhaltender Augenreizung: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
P362 Kontaminierte Kleidung ausziehen und vor erneutem Tragen waschen.

alpha-Arbutin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Arbutin is naturally found in plant sources such as Bearberry, Cranberry and Mulberry, which essentially prevents the formation of melanin (the pigment that creates skin colour). The chemically synthesised version of this plant extract is known as Alpha Arbutin which is used as a topical skin brightening agent to treat sun spots, pigmentation and scars caused by sun damage and breakouts. It also has antioxidant properties, which protect the skin from potential sun damage. Along with Retinol, it is a fairly common ingredient in anti-ageing products to treat age spots, fine lines and wrinkles. alpha-Arbutin-1.jpg

Chemische Eigenschaften

alpha-Arbutin is White Solid

Verwenden

alpha-Arbutin is a component used in the skin-whitening cosmetics.

Definition

Alpha arbutin, also called Hydroquinone β-D-glucopyranoside, is a naturally occurring antioxidant and skin brightener that is naturally found in the bearberry plant. It reduces melanin formation, improving the appearance of age spots, freckles, melasma, and post-inflammatory pigmentation.

benefits

Ensures an even skin tone after only one month;Reduces the degree of skin tanning after UV exposure;Helps to minimize the appearance of liver spots.

Biologische Funktion

Alpha arbutin acts as a tyrosinase competitive inhibitor and also slows melanosome maturation (the organelles that synthesize and store melanin or pigment).3 This is significant because it works on two different mechanisms of pigmentation. Melanin is derived from the amino acid tyrosine and this conversion is regulated by the enzyme tyrosinase. Alpha arbutin is similar in structure to tyrosine, which fits into tyrosinase, needed for melanogenesis. This means that alpha arbutin is reversibly competing with tyrosine for a spot on the enzyme and not inhibiting cell viability, so therefore is not cytotoxic. By targeting tyrosinase, the rate-limiting enzyme in melanin formation, as well as slowing production of the organelles that produce melanin, alpha arbutin is a potent skin brightening agent.

Allgemeine Beschreibung

α-Arbutin is a glycosylated hydroquinone and an anomer of naturally occurring arbutin. It is a potent inhibitor of tyrosinase, a vital enzyme involved in epidermal melanin biosynthesis. α-Arbutin finds extensive application as a powerful skin-lightening agent in cosmetic industries.

Mechanism of action

Alpha arbutin is frequently marketed as a safer alternative to hydroquinone (a popular skin-lightening ingredient that has been banned in Europe and Australia). It has similar results in brightening skin but without the dangerous bleaching process. Instead, it reduces skin’s pigment production by suppressing the enzymes that stimulate melanin. This also slows down the process by which UV light causes pigmentation, so it both prevents and treats pigmentation issues.

Nebenwirkungen

Alpha arbutin is an active compound. Using too many active agents together can cause harshness to your skin.
For sensitive skin, using too much product containing alpha arbutin can cause a burning sensation on your face or skin.
Using moisturisers just after applying alpha arbutin cream or gel may not work well on your skin. It is a light compound which does not absorb well into the skin if topped over a moisturiser.
Alpha arbutin side effects occur when applied on cracked skin. It is suitable for topical use but when it comes in contact with an exposed wound, it causes unbearable irritation.

alpha-Arbutin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


alpha-Arbutin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 626)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Huzhou Haipu Chemical Co.,Ltd
+86-0572-+86-0572-2526078 +8613757061525
xatyang@acetylacetone.net China 16 58
Watson Biotechnology Co.,Ltd
+86-18186686046 +86-18186686046
sales01@watsonbiotech.cn China 5804 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +8618949832763
info@tnjchem.com China 2986 55
ZhenYiBio Technology Inc
+8615309206328
alexxue@zhenyibio.com China 296 58
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118
xie@china-sinoway.com China 988 58
LEAP CHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 24727 58
Hebei Shengyang Water Conservancy Engineering Co., Ltd.
+8615373025980
clara@hbshengyang.com China 874 58
Chongqing Zhihe Biopharmaceutical Co., Ltd.
+8618580541567
sales@zhswyy.com China 303 58
Wuhan Fortuna Chemical Co.,Ltd
+8618007136271
hk@fortunachem.com China 5998 58
Hangzhou Lin'an tianhong biotechnology co.,ltd.
+86-0571-58605786 +8617758008775
admin@tianhongsw.com China 42 58

84380-01-8()Verwandte Suche:


  • alpha-arbutin
  • Hydroquinone O-α-D-Glucopyranoside
  • 4-Hydroxyphenyl a-D-glucopyranoside
  • 4-hydroxyphenyl alpha-D-glucopyranoside
  • Alpha bear
  • α-arbutin 84380-01-8
  • (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol
  • LGB-AA
  • Alpha Arbutin 98%
  • 4-hydroxyphenyl-D-lucopyranoside
  • alpha-Arbutoside
  • α-D-Glucopyranoside, 4-hydroxyphenyl
  • a-D-Glucopyranoside, 4-hydroxyphenyl
  • Skin whitening alpha-arbutin
  • Alpha-Arbutin Skin Whitening Alpha Arbutin Powder
  • Arbutin /Alpha Arbutin
  • Alpha-Arbutin CAS 84380-01-8 4-Hydroquinone-Alpha-D-Glucopyranoside
  • alpha-ArbutinQ: What is alpha-Arbutin Q: What is the CAS Number of alpha-Arbutin
  • 4-hydroquinone-alpha-d-glucopyranoside
  • a-Arbutin
  • (2R,3S,4S,5R,6S)-2-(HYDROXYMETHYL)-6-(4-HYDROXYPHENOXY)TETRAHYDROPYRAN-3,4,5-TRIOL
  • (2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydro-2H-pyran-3,4,5-triol
  • Alpha Arbutin Powder
  • Α-ARBUTIN
  • α-Arbutin
  • Alpha-Arbutin For Skin Care
  • Manganese chloride 7773-01-5
  • alphTXB-Arbutin
  • 4-Hydroxyphenyl α-D-Glucopyranoside
  • Hydroquinone O-α-D-Glucopyranoside
  • Alpha-Arbutin whitening raw materials for cosmetic
  • Alpha-Arbutin For Lightening/Whitening Cosmetic Products.
  • 84380-01-8
  • C12H17O7
  • Plant extract
  • Aromatics
  • Carbohydrates & Derivatives
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • 84380-01-8
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