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HISPIDIN

HISPIDIN Struktur
555-55-5
CAS-Nr.
555-55-5
Englisch Name:
HISPIDIN
Synonyma:
Hispidine;Hispidin - CAS 555-55-5 - Calbiochem;6-(3,4-Dihydroxystyryl)-4-hydroxy-2-pyrone;6-(3,4-Dihydroxystyryl)-4-hydroxy-2H-pyran-2-one;(E)-6-(3,4-Dihydroxystyryl)-4-hydroxy-2H-pyran-2-one;4-hydroxy-6-(3,4-dihydroxystyryl)-2-pyrone (hispidine);2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-6-hydroxy-4-pyranone;6-[(E)-2-(3,4-Dihydroxyphenyl)vinyl]-4-hydroxy-2H-pyran-2-one;(E)-6-[2-(3,4-Dihydroxyphenyl)ethenyl]-4-hydroxy-2H-pyran-2-one;6-[(1E)-2-(3,4-Dihydroxyphenyl)ethenyl]-4-hydroxy-2H-pyran-2-one
CBNumber:
CB3500046
Summenformel:
C13H10O5
Molgewicht:
246.22
MOL-Datei:
555-55-5.mol

HISPIDIN Eigenschaften

Schmelzpunkt:
312-315℃
Siedepunkt:
500.5±50.0 °C(Predicted)
Dichte
1.657
storage temp. 
-20°C
L?slichkeit
DMSO: >10 mg/mL
pka
4.90±0.30(Predicted)
Aggregatzustand
solid
Farbe
yellow to brown
maximale Wellenl?nge (λmax)
369nm(MeOH)(lit.)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
WGK Germany  3
HS Code  2932.20.3000
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H317 Kann allergische Hautreaktionen verursachen. Sensibilisierung der Haut Kategorie 1A Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
Sicherheit
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

HISPIDIN Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Hispidin is a polyphenol originally isolated from P. hispidus that has diverse biological activities, including antioxidant, anti-inflammatory, and cytoprotective properties. In a trolox equivalent antioxidant capacity (TEAC) assay, hispidin scavenges radicals at 14.47 equivalents of trolox . It inhibits transcriptional activity of NF-κB, decreases inducible nitric oxide synthase (iNOS) expression, and decreases the generation of reactive oxygen species (ROS) in LPS-induced macrophage RAW 264.7 cells. Hispidin inhibits apoptosis and increases insulin secretion in hydrogen peroxide-treated RINm5F pancreatic β-cells. It inhibits protein kinase C β (PKCβ; IC50 = 2 μM) with no activity against alkaline phosphatase. Hispidin also inhibits β-secretase (BACE1; IC50 = 4.9 μM) and prolyl endopeptidase (PE; IC50 = 16 μM) but not other serine proteases when used at a concentration of 40 μM (0.6, 0, 8.2, and 3.1% inhibition of chymotrypsin, trypsin, elastase, and tumor necrosis factor-α converting enzyme (TACE), respectively).

Verwenden

Hispidin is a naturally occuring precursor to fungal luciferin responsible for luminosity in mushrooms.

Definition

ChEBI: Fungal metabolite first found in basidiomycete Inonotus hispidus (formerly Polyporus hispidus).

Allgemeine Beschreibung

Hispidin is a phenolic compound, that is obtained from a medicinal mushroom, Phellinus linteus.

HISPIDIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

HISPIDIN Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 73)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512
 info@tianfuchem.com China 21634 55
Nanjing Finetech Chemical Co., Ltd. 		025-85710122 17714198479
sales@fine-chemtech.com CHINA 885 55
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 49374 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-87569266 15319487004
 1015@dideu.com China 3942 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Finetech Industry Limited 		+86-27-87465837 +8618971612321
 info@finetechnology-ind.com China 9639 58
Dayang Chem (Hangzhou) Co.,Ltd. 		571-88938639 +8617705817739
 info@dycnchem.com China 52849 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490
 info@gihichemicals.com China 49978 58

555-55-5()Verwandte Suche:

  • 6-[(E)-2-(3,4-Dihydroxyphenyl)vinyl]-4-hydroxy-2H-pyran-2-one
  • 4-hydroxy-6-(3,4-dihydroxystyryl)-2-pyrone (hispidine)
  • (E)-6-[2-(3,4-Dihydroxyphenyl)ethenyl]-4-hydroxy-2H-pyran-2-one
  • 6-(3,4-Dihydroxystyryl)-4-hydroxy-2H-pyran-2-one
  • 6-(3,4-Dihydroxystyryl)-4-hydroxy-2-pyrone
  • 6-[(1E)-2-(3,4-Dihydroxyphenyl)ethenyl]-4-hydroxy-2H-pyran-2-one
  • Hispidine
  • 2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-6-hydroxy-4-pyranone
  • Hispidin - CAS 555-55-5 - Calbiochem
  • 2H-Pyran-2-one, 6-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]-4-hydroxy-
  • (E)-6-(3,4-Dihydroxystyryl)-4-hydroxy-2H-pyran-2-one
  • Endogenous Metabolite,inhibit,anti-dementia,anti-diabetic,fungal,properties,PKC,Hispidin,Protein kinase C,Inhibitor,anti-oxidant,anti-cancer,metabolite
  • 555-55-5
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