Trimethadion
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Trimethadion Eigenschaften
- Schmelzpunkt:
- 45-46°C
- Siedepunkt:
- 78-80°C 5mm
- Dichte
- 1.3075 (rough estimate)
- Brechungsindex
- 1.4290 (estimate)
- Flammpunkt:
- 78-80°C/5mm
- storage temp.
- Inert atmosphere,Room Temperature
- L?slichkeit
- Soluble in water, very soluble in ethanol (96 per cent).
- pka
- -2.18±0.40(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Wasserl?slichkeit
- Soluble in water 50 g/L.
- Merck
- 14,9706
- BRN
- 121627
- CAS Datenbank
- 127-48-0(CAS DataBase Reference)
- EPA chemische Informationen
- Trimethadione (127-48-0)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher | T | ||
---|---|---|---|
R-S?tze: | 61-20/21/22 | ||
S-S?tze: | 53-22-36/37/39-45 | ||
WGK Germany | 3 | ||
RTECS-Nr. | RQ2100000 |
Bildanzeige (GHS) | |||||||||||||||
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Alarmwort | Achtung | ||||||||||||||
Gefahrenhinweise |
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Sicherheit |
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Trimethadion Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R61:Kann das Kind im Mutterleib sch?digen.R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-S?tze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.S22:Staub nicht einatmen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
Chemische Eigenschaften
White, granular, crystalline substance; camphor-like odor. Soluble in water; freely soluble in alcohol, chloroform, and ether; pH 6.0 (5% solution).Verwenden
3,5,5-Trimethyloxazolidine-2,4-dione is used in the control of absence (petit mal) seizures that are refractory to treatment with other medications. It is used in the treatment of epilepsy.Hazard
May have adverse side effects; toxic in overdose.Clinical Use
Trimethadione is indicated only for control of absence seizures refractory to treatment with other AEDs. It is ineffective against other seizure types. Trimethadione is a pro-drug and is metabolized by N-demethylation to dimethadione, which is effective in the pentylenetetrazole test, which acts by decreasing T-type calcium currents. Trimethadione is rapidly absorbed, is not protein bound, and has a half-life of 16 to 24 hours. The half-life of dimethadione, however, is substantially longer (i.e., 6–13 days), and dimethadione accumulates to concentrations greater than the parent drug. Because of its potentially fatal side effects. including aplastic anemia, nephrosis, idiosyncratic rashes, and exfoliative dermatitis, trimethadione rarely is used today.Trimethadion Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Methyljodid
Harnstoff
Natrium
Ethanol
Ethylharnstoff
2(5H)-Oxazolone, 4-methoxy-5,5-dimethyl-
5,5-Dimethyl-2-thioxooxazolidin-4-one
2,4-Oxazolidinedione, 3,5-dimethyl-
Ethyl-2-hydroxy-2-methylpropionat
Dimethadion
Diethylether
Methylisocyanat
Kohlenstoffdioxid
Dimethylsulfat
Downstream Produkte
Trimethadion Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 98)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32161 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6312 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 22787 | 58 |
Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 |
sales@chemhifuture.com | China | 3135 | 58 |
TargetMol Chemicals Inc. | |
support@targetmol.com | United States | 38631 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57505 | 58 |
TargetMol Chemicals Inc. | +8613564774135 |
zijue.cai@tsbiochem.com | United States | 19885 | 58 |
Mainchem Co., Ltd. | +86-0592-6210733 |
sale@mainchem.com | China | 32343 | 55 |
Meryer (Shanghai) Chemical Technology Co., Ltd. | 021-61259108 18621169109 |
market03@meryer.com | China | 40228 | 62 |
Alfa Aesar | 400-6106006 |
saleschina@alfa-asia.com | China | 30123 | 84 |
127-48-0(Trimethadion)Verwandte Suche:
O,O-Diethyl-O-1-phenyl-1,2,4-triazol-3-ylthio-phosphat
Metribuzin
Natriumvalproat
Gabapentin
3-Ethyl-5,5-dimethyloxazolidin-2,4-dion
N-3,5-Dichlorphenyl-5-methyl-5-vinyl-1,3-oxazolidin-2,4-dion
Trimethadion
Vinzolidin
- TRIMETHADIONE
- 3,5,5-TRIMETHYLOXAZOLIDINE-2,4-DIONE
- 3,5,5-TRIMETHYLOXOZOLIDINE-2,4-DIONE
- 2,4-Oxazolidinedione, 3,5,5-trimethyl-
- 3,3,5-Trimethyl-2,4-diketooxazolidine
- 3,5,5-Trimethyl-1,3-oxazolidine-2,4-dione
- 3,5,5-Trimethyl-2,4-oxazolidinedione
- 3,5,5-Trimethyl-2,4-oxazolidinedionenol
- 3,5,5-trimethyl-4-oxazolidinedione
- 3,5,5-Trojmetylooksazolidyno-2,4-dion
- A 2297
- a2297
- Absentol
- Absetil
- Convenixa
- Convexina
- Edion
- Epidione
- Epidone
- Epixal
- Etydion
- Minoaleuiatin
- minoaleviatin
- Mino-aleviatin
- Neo-absentol
- Petidion
- Petidon
- Petilep
- Petimalin
- Pitmal
- Ptimal
- Tioxanona
- Tredione
- Tricione
- Tridilona
- Tridion
- Tridione
- Tridone
- Trilidona
- Trimedal
- Trimedone
- Trimetadione
- Trimethadion
- Trimethdione
- Trimethin
- Trioxanona
- Triozanona
- Tromedone
- Troxidone
- 3,5,5-trimethyloxazolidine-2,4-quinone
- Trimethadione (200 mg)
- trimethadioine
- 3,5,5-Trimethyl-2,4-dioxooxazolidine
- -Trimethyloxazolidine-2
- Trimethadione CRS
- 3,5,5-TRIMETHYLOXAZOLIDINE-2,4-DIONE USP/EP/BP
- Trimethadione[Tridione
- Trimethadione (1690000)