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6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Struktur
1016636-76-2
CAS-Nr.
1016636-76-2
Englisch Name:
6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one
Synonyma:
6-BroMo-2-chloro-8-cyclopentyl-5-Methyl-8H-pyrido[2,3-d]pyriMidin-7-one;6-broMo-2-chloro-8-cyclopentyl-5-;6-bromo-2-chloro-8-cyclopentyl-5-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one;PALBOCI;Palbociclib-015;PALBOCICLIB-PB3;Palbociclib nuclear;Pabucilib impurity 8;Palbociclib Impurity I;Palbociclib Intermediate 3
CBNumber:
CB32554175
Summenformel:
C13H13BrClN3O
Molgewicht:
342.62
MOL-Datei:
1016636-76-2.mol

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Eigenschaften

Schmelzpunkt:
190-192°C
Siedepunkt:
468.4±45.0 °C(Predicted)
Dichte
1.645±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
L?slichkeit
Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly, Sonicated)
Aggregatzustand
Solid
pka
-0.61±0.20(Predicted)
Farbe
White
InChI
InChI=1S/C13H13BrClN3O/c1-7-9-6-16-13(15)17-11(9)18(12(19)10(7)14)8-4-2-3-5-8/h6,8H,2-5H2,1H3
InChIKey
HJQCAEDIUJXGCQ-UHFFFAOYSA-N
SMILES
C1(Cl)=NC=C2C(C)=C(Br)C(=O)N(C3CCCC3)C2=N1
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher T
R-S?tze: 25
S-S?tze: 45
RIDADR  UN2811
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H317 Kann allergische Hautreaktionen verursachen. Sensibilisierung der Haut Kategorie 1A Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
Sicherheit
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one is a pharmaceutical intermediate that can be used to synthesize Palbociclib, an inhibitor of cyclin-dependent kinases (CDKs) 4 and 6 for the treatment of breast cancer.

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 499)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Senova Technology Co. Ltd.
+86-0755-86703119 +8618503098836
 info@senovatech.com China 351 58
AstaTech(Chengdu) Biopharmaceutical Corp.
+86-02882666559 +86-15884417729
 gjpu@astatech.com.cn China 308 58
ChemExpress
+86-021-58950125 +86-021-58950125;
 info@chemexpress.com China 781 58
Unibest Industrial Co.,Ltd.
+86-8657427855777 +86-18758850676
 info@unibestcn.com China 227 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580
 cooperation@kean-chem.com China 40066 58
Shanghai Joiny Pharmaceutical Co.,LTD 		+8613681955282
 gyd@joiny-pharma.com China 311 58
SHANDONG BOYUAN PHARMACEUTICAL CO., LTD. 		+86-0531-69954981 +8615666777973
 dwyane.wang@boyuanpharm.com China 211 58
hebei hongtan Biotechnology Co., Ltd 		+86-86-1913198-3935 +8617331935328
 sales03@chemcn.cn China 970 58
ShenZhen H&D Pharmaceutical Technology Co., LTD 		+8618627948422
 sale@hdimpurity.com China 3389 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806
 sales@capot.com China 29791 60

1016636-76-2()Verwandte Suche:

  • 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-on
  • 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one
  • Pyrido[2,3-d]pyriMidin-7(8H)-one, 6-broMo-2-chloro-8-cyclopentyl-5-Methyl-
  • PALBOCICLIB-PB3
  • 6-bromo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one(For Palbociclib)
  • 6-bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7-one
  • PALBOCI
  • Palbociclib-015
  • 6-bromo-2-chloro-8-cyclopentyl-5-methylpyridino[2,3-d]pyrimidin-7(8H)-one
  • Palbociclib Intermediate 3
  • 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one(1016636-76-2)
  • Palbociclib Impurity I
  • 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2
  • -broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one
  • 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one ISO 9001：2015 REACH
  • 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido {2,3} pyrimidin-7-(8H)-one
  • 6-bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)
  • 6-bromo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one 6-
  • 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidi...
  • 6-broMo-2-chloro-8-cyclopentyl-5-
  • 6-BroMo-2-chloro-8-cyclopentyl-5-Methyl-8H-pyrido[2,3-d]pyriMidin-7-one
  • 6-bromo-2-chloro-8-cyclopentyl-5-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one
  • Palbociclib nuclear
  • 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(9H)-one
  • 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido {2,3} pyrimidine-7-(8H)-one
  • 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-
  • Pabucilib impurity 8
  • 1016636-76-2
  • 1016636-76-3
  • 2174002-19-8
  • Palbociclib
  • PD 0332991
  • Anticancer
  • 1016636-76-2
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