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Dihydrocapsaicin

Dihydrocapsaicin Struktur
19408-84-5
CAS-Nr.
19408-84-5
Englisch Name:
Dihydrocapsaicin
Synonyma:
CAPSAICINE;N-(3-Methoxy-4-hydroxybenzyl)-8-methylnonanamide;(E)-8-METHYL-NON-6-ENOIC ACID 4-HYDROXY-3-METHOXY-BENZYLAMIDE;FEMA 2787;FEMA 3404;CCRIS1589;(E)-CAPSAICIN;ihydrocapsaicin;Dihydrocapsaicin;CAPSAICIN, NATURAL
CBNumber:
CB3112966
Summenformel:
C18H29NO3
Molgewicht:
307.43
MOL-Datei:
19408-84-5.mol

Dihydrocapsaicin Eigenschaften

Schmelzpunkt:
62-65 °C(lit.)
Siedepunkt:
497.4±35.0 °C(Predicted)
Dichte
1.026±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
L?slichkeit
H2O: insoluble
pka
9.76±0.20(Predicted)
Aggregatzustand
White to off-white solid.
Farbe
White to off-white
BRN 
2815150
InChIKey
XJQPQKLURWNAAH-UHFFFAOYSA-N
LogP
3.556 (est)
CAS Datenbank
19408-84-5(CAS DataBase Reference)
EPA chemische Informationen
Dihydrocapsaicin (19408-84-5)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher T
R-S?tze: 25-37/38-41-42/43-36/37/38
S-S?tze: 22-26-28-36/39-45-36/37/39
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS-Nr. RA8530000
10-21
HazardClass  6.1(a)
PackingGroup  II
HS Code  29399990
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H301 Giftig bei Verschlucken. Akute Toxizit?t oral Kategorie 3 Achtung GHS hazard pictogramssrc="/GHS06.jpg" width="20" height="20" /> P264, P270, P301+P310, P321, P330,P405, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P301+P310 BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

Dihydrocapsaicin Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R25:Giftig beim Verschlucken.
R37/38:Reizt die Atmungsorgane und die Haut.
R41:Gefahr ernster Augensch?den.
R42/43:Sensibilisierung durch Einatmen und Hautkontakt m?glich.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S28:Bei Berührung mit der Haut sofort abwaschen mit viel . . . (vom Hersteller anzugeben).
S36/39:Bei der Arbeit geeignete Schutzkleidung und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Beschreibung

Dihydrocapsaicin is a terpene alkaloid that has been found in Capsicum and has diverse biological activities. It is active against E. faecalis, B. subtilis, S. aureus, P. aeruginosa, K. pneumoniae, E. coli, and C. albicans (MICs = 0.6-10 μg/ml). Dihydrocapsaicin scavenges DPPH and ABTS radicals in cell-free assays. It increases LC3-II, a marker of autophagy, and catalase levels and reduces reactive oxygen species (ROS) production in normal WI38 lung fibroblasts and H1299, but not A549 or H460, lung cancer cells when used at a concentration of 200 μM. Dihydrocapsaicin is an agonist of transient receptor potential vanilloid 1 (TRPV1) and inhibits NETosis induced by phorbol 12-myristate 13-acetate (TPA; ) in isolated human neutrophils. It induces cortical and systemic hypothermia and reduces infarct volume in a rat model of ischemia-reperfusion injury induced by middle cerebral artery occlusion (MCAO) when administered at a dose of 0.5 mg/kg, i.p.

Chemische Eigenschaften

White Solid

Verwenden

Dihydrocapsaicin has been used as a reference standard for the identification of dihydrocapsaicin in blood and tissue samples by high performance liquid chromatography (HPLC) combined with tandem mass spectrometry (MS) and in tomato-based salsas by enzyme immunoassay (EIA) and LC with fluorescent detection.
It may be used as a reference standard for the determination of dihydrocapsaicin in Capsicum fruit samples by HPLC equipped with a Surveyor photodiode array (PDA) detector and in rat plasma by HPLC-triple quadrupole MS with electrospray ionization (ESI) in selected reaction monitoring (SRM) mode.

Allgemeine Beschreibung

Dihydrocapsaicin belongs to the capsaicinoid group of compounds which are responsible for the pungency of capsicum fruits.

Dihydrocapsaicin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Dihydrocapsaicin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 337)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118
xie@china-sinoway.com China 988 58
BINBO BIOLOGICAL CO.,LTD
+8618629063126
info@binbobiological.com China 368 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29884 58
Zhejiang ZETian Fine Chemicals Co. LTD
+8618957127338
stella@zetchem.com China 2136 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897
sales@biopurify.com China 3772 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768
sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58
Shaanxi Pioneer Biotech Co., Ltd .
+8613259417953
sales@pioneerbiotech.com China 3000 58

19408-84-5()Verwandte Suche:


  • CAPSAICIN, NATURAL
  • (E)-CAPSAICIN
  • (E)-N-([4-HYDROXY-3-METHOXYPHENYL]METHYL)8-METHYL-6-NONEAMIDE
  • FEMA 3404
  • FEMA 2787
  • N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-6E-NONENAMIDE
  • N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-6-NONENAMIDE
  • TRANS-8-METHYL-N-VANILLYL-6-NONENAMIDE
  • 6,7-dihydrocapsaicin
  • 8-methyl-n-vanillyl-nonanamid
  • Dihydrocapsaicin, froM CapsicuM annuuM
  • N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methylnonenamide
  • -8-methylnonanamide
  • N-(4-Hydroxy-3-methoxybenzyl)
  • 8-METHYL-N-VANILLYL-TRANS-6-NONENAMIDE
  • 8-METHYL-N-VANILLYL-6-NONENEAMIDE
  • 8-methyl-N-vanillylnonanamide approx.*90% from ca
  • 8-METHYL-N-VANILLYLNONANAMIDE APPROX.*90 % FROM CAPS
  • DIHYDROCAPSAICIN, NATURAL
  • Dihydrocapsaicin std.
  • 8-METHYL-N-VANILLYLNONANAMIDE 90+%
  • CAPSAICIN/8-METHYL-NONANOICACIDVANILLYLAMIDE
  • (E)-N-[(4-Hydroxy-3-methoxyphenyl)-8-methyl-6-nonenamide
  • Dihydrocapsaicin Standard
  • 8-Methyl-N-vanillylnonanamide
  • Dihydrocapsaicin
  • N-(4-hydroxy-3-methoxy-benzyl)-8-methyl-pelargonamide
  • Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide
  • N-(4-hydroxy-3-Methoxybenzyl)-8-MethylnonanaMide
  • Dihydrocapsaicin (25 mg)
  • Dihydrocapsaicin, 98%, from Capsicum annuum L.
  • Dihydro capsaicin - Natural extraction
  • Dihydro capsaicin - Synthetic
  • N-[(4-hydroxy-3-methoxy-1-cyclohexa-2,4-dienyl)methyl]-8-methyl-6-nonenamide
  • Dihydrocapsaicin, 98%, from Capsicum annuum
  • CCRIS1589
  • Nonanamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-
  • ihydrocapsaicin
  • Dihydrocapsaicin USP/EP/BP
  • 19408-84-5 Dihydrocapsaicin
  • N-(3-Methoxy-4-hydroxybenzyl)-8-methylnonanamide
  • (E)-8-METHYL-NON-6-ENOIC ACID 4-HYDROXY-3-METHOXY-BENZYLAMIDE
  • CAPSAICINE
  • Valine Impurity 77
  • DIHYDROCAPSAICIN(P) 10mg
  • Dihydrocapsaicin-RM
  • Dihydrocapsaicin in Methanol
  • 19408-84-5
  • C18H29NO3
  • Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P.
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