2-Hydroxy-1,4-naphthochinon Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R68:Irreversibler Schaden m?glich.
R36:Reizt die Augen.
R22:Gesundheitssch?dlich beim Verschlucken.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Aussehen Eigenschaften
C10H6O3; Farblose bis gelbe Nadeln, geruchlos.
Gefahren für Mensch und Umwelt
Gesundheitsschädlich beim Einatmen, Verschlucken und Berührung mit der Haut. Reizt Haut, Augen und Atmungsorgane.
Thermische Belastung und Berührung mit starken Oxidationsmitteln vermeiden.
Schutzma?nahmen und Verhaltensregeln
Lichtgeschützt lagern
Schutzhandschuhe als kurzzeitiger Staubschutz.
Verhalten im Gefahrfall
Trocken aufnehmen, Staubbildung und Substanzkontakt vermeiden, der Entsorgung zuführen.
Kohlendioxid, Wasser im Sprühstrahl, Pulver, Schaum.
Erste Hilfe
Nach Hautkontakt: Mit reichlich Wasser abwaschen.
Nach Augenkontakt: Mit reichlich Wasser bei geöffnetem Lidspalt mindesten 10 Minuten spülen, Augenarzt hinzuziehen.
Nach Einatmen: Frischluft, notfalls Beatmung.
Nach Verschlucken: Reichlich Wasser trinken lassen, Erbrechen herbeiführen, Arzt hinzuziehen.
Nach Kleidungskontakt: Kontaminierte Kleidung sofort ausziehen.
Ersthelfer: siehe gesonderten Anschlag
Sachgerechte Entsorgung
In Aceton gelöst zu den halogenfreien, organischen Lösemittelabfällen.
Chemische Eigenschaften
Yellow crystal powder
History
Lawsone (CI Natural Orange 6; CI 75420), also known as henna and isojuglone, occurs in the shrub henna (Lawsone alba). In England, the plant is known as Egyptian privet. The dye was extracted from the leaves of the plant, using sodium bicarbonate, and the extracts used to dye protein fibers an orange shade. Henna is probably the oldest cosmetic known. The ancient Egyptians used it as a hair dye and for staining fingernails. It is said that Mohammed dyed his beard with henna. Lawsone has been identified as 2-hydroxy-1,4-naphthoquinone. It has been synthesized by the Thiele acetylation of 1,4-naphthoquinone followed by hydrolysis and oxidation.
Verwenden
antifungal, sunscreen, antibacterial, antineoplastic
Definition
A coloring principle obtained from dried leaves of certain tropical plants (North Africa, India).
Allgemeine Beschreibung
Yellow prisms or yellow powder.
Air & Water Reaktionen
Insoluble in water.
Reaktivit?t anzeigen
Phenols, such as 2-Hydroxy-1,4-naphoquinone, do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has Ka = 1.3 x 10^[-10]). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Such heating may initiate polymerization of the organic compound. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid. Nitrated phenols often explode when heated. Many of them form metal salts that tend toward detonation by rather mild shock.
Health Hazard
ACUTE/CHRONIC HAZARDS: 2-Hydroxy-1,4-naphoquinone may be absorbed through the skin and can cause skin irritation.
Brandgefahr
Flash point data for 2-Hydroxy-1,4-naphoquinone are not available but 2-Hydroxy-1,4-naphoquinone is probably combustible.
Kontakt-Allergie
Henna, prepared by powdering the dried leaves of henna plant (Lawsonia inermis L.), is used for coloring and conditioning hair and nails, particularly by Muslims or Hindus. It contains Lawsone, which very rarely induces contact allergy. Most dermatitis caused by “black henna” is due to PPD and derivatives
l?uterung methode
Crystallise Lawsone B from *C6H6 or AcOH (m 192.5o, 195-196o). It sublimes in a vacuum (m 194o). It has UV with max at 455nm (aqueous NaOH). [Beilstein 8 H 300, 8 I 635, 8 II 344, 8 III 2543, 8 IV 2360.]
2-Hydroxy-1,4-naphthochinon Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Sulfamins?ure, Monoammonium-Salz
1,4-Naphthalindion
1,2-Naphthochinon
Naphthalin-1,2,4-triyltriacetat
Naphthalin-1,2,4-triol
2-Naphthalenol, 1,4-dimethoxy-
Naphthalin-1,3-diol
2-METHOXY-1,4-NAPHTHOQUINONE
4-methoxynaphthalene-1,2-dione
Naphthalin-1,2-diol
2-Chloro-3-hydroxy-1,4-naphthoquinone
2-hydroxy-3-iodonaphthalene-1,4-dione
Naphthalin-1,4-diol
2-Naphthol
1,2,3,4-Tetrahydro-1-naphthalinon
Methyl-2-naphthylether
o-Nitrobenzolthiol
Downstream Produkte